BDBM85528 CAS_3045226::NSC_3045226::Ro 60-0175

SMILES: CC(N)Cn1ccc2cc(F)c(Cl)cc12

InChI Key: InChIKey=XJJZQXUGLLXTHO-UHFFFAOYSA-N

Data: 11 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 85528   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM85528 (CAS_3045226 | NSC_3045226 | Ro 60-0175) Show SMILES CC(N)Cn1ccc2cc(F)c(Cl)cc12 Show InChI InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	0.550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database									Naunyn Schmiedebergs Arch Pharmacol 365: 242-52 (2002) Article DOI: 10.1007/s00210-001-0505-y BindingDB Entry DOI: 10.7270/Q2W37TWZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM85528 (CAS_3045226 | NSC_3045226 | Ro 60-0175) Show SMILES CC(N)Cn1ccc2cc(F)c(Cl)cc12 Show InChI InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	0.890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cerebrus Ltd Curated by PDSP Ki Database									Br J Pharmacol 128: 13-20 (1999) Article DOI: 10.1038/sj.bjp.0702751 BindingDB Entry DOI: 10.7270/Q2GH9GH2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM85528 (CAS_3045226 | NSC_3045226 | Ro 60-0175) Show SMILES CC(N)Cn1ccc2cc(F)c(Cl)cc12 Show InChI InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yamanouchi Pharmaceutical Co., Ltd. Curated by PDSP Ki Database									Eur J Pharmacol 483: 37-43 (2004) Article DOI: 10.1016/j.ejphar.2003.10.004 BindingDB Entry DOI: 10.7270/Q2ZG6QTV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM85528 (CAS_3045226 | NSC_3045226 | Ro 60-0175) Show SMILES CC(N)Cn1ccc2cc(F)c(Cl)cc12 Show InChI InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	5.37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis Research Curated by PDSP Ki Database									Naunyn Schmiedebergs Arch Pharmacol 370: 114-23 (2004) Article DOI: 10.1007/s00210-004-0951-4 BindingDB Entry DOI: 10.7270/Q2M32TBD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM85528 (CAS_3045226 | NSC_3045226 | Ro 60-0175) Show SMILES CC(N)Cn1ccc2cc(F)c(Cl)cc12 Show InChI InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	6.03	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis Research Curated by PDSP Ki Database									Naunyn Schmiedebergs Arch Pharmacol 370: 114-23 (2004) Article DOI: 10.1007/s00210-004-0951-4 BindingDB Entry DOI: 10.7270/Q2M32TBD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM85528 (CAS_3045226 | NSC_3045226 | Ro 60-0175) Show SMILES CC(N)Cn1ccc2cc(F)c(Cl)cc12 Show InChI InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yamanouchi Pharmaceutical Co., Ltd. Curated by PDSP Ki Database									Eur J Pharmacol 483: 37-43 (2004) Article DOI: 10.1016/j.ejphar.2003.10.004 BindingDB Entry DOI: 10.7270/Q2ZG6QTV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM85528 (CAS_3045226 | NSC_3045226 | Ro 60-0175) Show SMILES CC(N)Cn1ccc2cc(F)c(Cl)cc12 Show InChI InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yamanouchi Pharmaceutical Co., Ltd. Curated by PDSP Ki Database									Eur J Pharmacol 483: 37-43 (2004) Article DOI: 10.1016/j.ejphar.2003.10.004 BindingDB Entry DOI: 10.7270/Q2ZG6QTV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM85528 (CAS_3045226 | NSC_3045226 | Ro 60-0175) Show SMILES CC(N)Cn1ccc2cc(F)c(Cl)cc12 Show InChI InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	26.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database									Naunyn Schmiedebergs Arch Pharmacol 365: 242-52 (2002) Article DOI: 10.1007/s00210-001-0505-y BindingDB Entry DOI: 10.7270/Q2W37TWZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM85528 (CAS_3045226 | NSC_3045226 | Ro 60-0175) Show SMILES CC(N)Cn1ccc2cc(F)c(Cl)cc12 Show InChI InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	32.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cerebrus Ltd Curated by PDSP Ki Database									Br J Pharmacol 128: 13-20 (1999) Article DOI: 10.1038/sj.bjp.0702751 BindingDB Entry DOI: 10.7270/Q2GH9GH2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM85528 (CAS_3045226 | NSC_3045226 | Ro 60-0175) Show SMILES CC(N)Cn1ccc2cc(F)c(Cl)cc12 Show InChI InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	36.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis Research Curated by PDSP Ki Database									Naunyn Schmiedebergs Arch Pharmacol 370: 114-23 (2004) Article DOI: 10.1007/s00210-004-0951-4 BindingDB Entry DOI: 10.7270/Q2M32TBD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM85528 (CAS_3045226 | NSC_3045226 | Ro 60-0175) Show SMILES CC(N)Cn1ccc2cc(F)c(Cl)cc12 Show InChI InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	447	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cerebrus Ltd Curated by PDSP Ki Database									Br J Pharmacol 128: 13-20 (1999) Article DOI: 10.1038/sj.bjp.0702751 BindingDB Entry DOI: 10.7270/Q2GH9GH2
					More data for this Ligand-Target Pair