BindingDB PrimarySearch

BDBM85833 N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]- ethyl]-N-(2-nitrophenyl)cyclohexanecarboxamide::Rec 15/3079

SMILES: COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccc2[N+]([O-])=O)CC1

InChI Key: InChIKey=HVMKWKIPLGPYAR-UHFFFAOYSA-N

Data: 9 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 85833
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM85833 (N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]- ethyl]-N...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Recordati S.p.A. Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 1027-37 (2001) BindingDB Entry DOI: 10.7270/Q2F47MP3
Recordati S.p.A. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM85833 (N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]- ethyl]-N...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Recordati S.p.A. Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 1027-37 (2001) BindingDB Entry DOI: 10.7270/Q2F47MP3
Recordati S.p.A. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM85833 (N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]- ethyl]-N...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	5.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit&aagrove; di Firenze Curated by PDSP K_i Database									J Pharmacol Exp Ther 315: 109-17 (2005) Article DOI: 10.1124/jpet.105.087809 BindingDB Entry DOI: 10.7270/Q2VD6X2V
Universit&aagrove; di Firenze Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM85833 (N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]- ethyl]-N...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Recordati S.p.A. Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 1027-37 (2001) BindingDB Entry DOI: 10.7270/Q2F47MP3
Recordati S.p.A. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM85833 (N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]- ethyl]-N...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	81.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit&aagrove; di Firenze Curated by PDSP K_i Database									J Pharmacol Exp Ther 315: 109-17 (2005) Article DOI: 10.1124/jpet.105.087809 BindingDB Entry DOI: 10.7270/Q2VD6X2V
Universit&aagrove; di Firenze Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Homo sapiens (Human))	BDBM85833 (N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]- ethyl]-N...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit&aagrove; di Firenze Curated by PDSP K_i Database									J Pharmacol Exp Ther 315: 109-17 (2005) Article DOI: 10.1124/jpet.105.087809 BindingDB Entry DOI: 10.7270/Q2VD6X2V
Universit&aagrove; di Firenze Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Homo sapiens (Human))	BDBM85833 (N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]- ethyl]-N...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Recordati S.p.A. Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 1027-37 (2001) BindingDB Entry DOI: 10.7270/Q2F47MP3
Recordati S.p.A. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM85833 (N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]- ethyl]-N...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	871	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit&aagrove; di Firenze Curated by PDSP K_i Database									J Pharmacol Exp Ther 315: 109-17 (2005) Article DOI: 10.1124/jpet.105.087809 BindingDB Entry DOI: 10.7270/Q2VD6X2V
Universit&aagrove; di Firenze Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (RAT)	BDBM85833 (N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]- ethyl]-N...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit&aagrove; di Firenze Curated by PDSP K_i Database									J Pharmacol Exp Ther 315: 109-17 (2005) Article DOI: 10.1124/jpet.105.087809 BindingDB Entry DOI: 10.7270/Q2VD6X2V
Universit&aagrove; di Firenze Curated by PDSP K_i Database					More data for this Ligand-Target Pair