BDBM85863 CAS_170493-63-7::NSC_3045228::Ro 600332

SMILES: CC(N)Cn1ccc2c1-c1cc(C)ccc1C2(C)C

InChI Key: InChIKey=IPIHGDDHIVDPOJ-UHFFFAOYSA-N

Data: 4 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 85863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM85863 (CAS_170493-63-7 | NSC_3045228 | Ro 600332) Show SMILES CC(N)Cn1ccc2c1-c1cc(C)ccc1C2(C)C Show InChI InChI=1S/C17H22N2/c1-11-5-6-14-13(9-11)16-15(17(14,3)4)7-8-19(16)10-12(2)18/h5-9,12H,10,18H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Binding affinity against human 5-hydroxytryptamine 2C receptor using displacement of [3H]DOB				J Med Chem 40: 2762-9 (1997) Article DOI: 10.1021/jm970030l BindingDB Entry DOI: 10.7270/Q270845Q
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM85863 (CAS_170493-63-7 | NSC_3045228 | Ro 600332) Show SMILES CC(N)Cn1ccc2c1-c1cc(C)ccc1C2(C)C Show InChI InChI=1S/C17H22N2/c1-11-5-6-14-13(9-11)16-15(17(14,3)4)7-8-19(16)10-12(2)18/h5-9,12H,10,18H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database									Naunyn Schmiedebergs Arch Pharmacol 365: 242-52 (2002) Article DOI: 10.1007/s00210-001-0505-y BindingDB Entry DOI: 10.7270/Q2W37TWZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM85863 (CAS_170493-63-7 | NSC_3045228 | Ro 600332) Show SMILES CC(N)Cn1ccc2c1-c1cc(C)ccc1C2(C)C Show InChI InChI=1S/C17H22N2/c1-11-5-6-14-13(9-11)16-15(17(14,3)4)7-8-19(16)10-12(2)18/h5-9,12H,10,18H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database									Naunyn Schmiedebergs Arch Pharmacol 365: 242-52 (2002) Article DOI: 10.1007/s00210-001-0505-y BindingDB Entry DOI: 10.7270/Q2W37TWZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM85863 (CAS_170493-63-7 | NSC_3045228 | Ro 600332) Show SMILES CC(N)Cn1ccc2c1-c1cc(C)ccc1C2(C)C Show InChI InChI=1S/C17H22N2/c1-11-5-6-14-13(9-11)16-15(17(14,3)4)7-8-19(16)10-12(2)18/h5-9,12H,10,18H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Binding affinity against human 5-hydroxytryptamine 2A receptor using displacement of [3H]5-HT				J Med Chem 40: 2762-9 (1997) Article DOI: 10.1021/jm970030l BindingDB Entry DOI: 10.7270/Q270845Q
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM85863 (CAS_170493-63-7 | NSC_3045228 | Ro 600332) Show SMILES CC(N)Cn1ccc2c1-c1cc(C)ccc1C2(C)C Show InChI InChI=1S/C17H22N2/c1-11-5-6-14-13(9-11)16-15(17(14,3)4)7-8-19(16)10-12(2)18/h5-9,12H,10,18H2,1-4H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the rat				J Med Chem 40: 2762-9 (1997) Article DOI: 10.1021/jm970030l BindingDB Entry DOI: 10.7270/Q270845Q
					More data for this Ligand-Target Pair