BDBM86213 CAS_5126051::CHEMBL327783::CPCCOEt::NSC_5126051

SMILES: CCOC(=O)C12CC1C(N=O)c1ccccc1O2

InChI Key: InChIKey=FINYWNDRBPWDDL-UHFFFAOYSA-N

Data: 8 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 86213   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (RAT)	BDBM86213 (CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051) Show SMILES CCOC(=O)C12CC1C(N=O)c1ccccc1O2 Show InChI InChI=1S/C13H13NO4/c1-2-17-12(15)13-7-9(13)11(14-16)8-5-3-4-6-10(8)18-13/h3-6,9,11H,2,7H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development, Beerse Curated by PDSP Ki Database									Mol Pharmacol 63: 1082-93 (2003) Article DOI: 10.1124/mol.63.5.1082 BindingDB Entry DOI: 10.7270/Q2BV7F62
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (RAT)	BDBM86213 (CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051) Show SMILES CCOC(=O)C12CC1C(N=O)c1ccccc1O2 Show InChI InChI=1S/C13H13NO4/c1-2-17-12(15)13-7-9(13)11(14-16)8-5-3-4-6-10(8)18-13/h3-6,9,11H,2,7H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development, Beerse Curated by PDSP Ki Database									Mol Pharmacol 63: 1082-93 (2003) Article DOI: 10.1124/mol.63.5.1082 BindingDB Entry DOI: 10.7270/Q2BV7F62
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM86213 (CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051) Show SMILES CCOC(=O)C12CC1C(N=O)c1ccccc1O2 Show InChI InChI=1S/C13H13NO4/c1-2-17-12(15)13-7-9(13)11(14-16)8-5-3-4-6-10(8)18-13/h3-6,9,11H,2,7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonist potency against cloned human metabotropic glutamate receptor 1				J Med Chem 43: 2609-45 (2000) BindingDB Entry DOI: 10.7270/Q2DZ090Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM86213 (CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051) Show SMILES CCOC(=O)C12CC1C(N=O)c1ccccc1O2 Show InChI InChI=1S/C13H13NO4/c1-2-17-12(15)13-7-9(13)11(14-16)8-5-3-4-6-10(8)18-13/h3-6,9,11H,2,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonist potency against cloned metabotropic glutamate receptor 5				J Med Chem 43: 2609-45 (2000) BindingDB Entry DOI: 10.7270/Q2DZ090Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM86213 (CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051) Show SMILES CCOC(=O)C12CC1C(N=O)c1ccccc1O2 Show InChI InChI=1S/C13H13NO4/c1-2-17-12(15)13-7-9(13)11(14-16)8-5-3-4-6-10(8)18-13/h3-6,9,11H,2,7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist potency against cloned Metabotropic glutamate receptor 2				J Med Chem 43: 2609-45 (2000) BindingDB Entry DOI: 10.7270/Q2DZ090Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGluR4) (Homo sapiens (Human))	BDBM86213 (CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051) Show SMILES CCOC(=O)C12CC1C(N=O)c1ccccc1O2 Show InChI InChI=1S/C13H13NO4/c1-2-17-12(15)13-7-9(13)11(14-16)8-5-3-4-6-10(8)18-13/h3-6,9,11H,2,7H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)				J Med Chem 43: 2609-45 (2000) BindingDB Entry DOI: 10.7270/Q2DZ090Q
					More data for this Ligand-Target Pair
GRM8 (Homo sapiens (Human))	BDBM86213 (CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051) Show SMILES CCOC(=O)C12CC1C(N=O)c1ccccc1O2 Show InChI InChI=1S/C13H13NO4/c1-2-17-12(15)13-7-9(13)11(14-16)8-5-3-4-6-10(8)18-13/h3-6,9,11H,2,7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonist potency against cloned Metabotropic glutamate receptor 8 (mGluR-8).				J Med Chem 43: 2609-45 (2000) BindingDB Entry DOI: 10.7270/Q2DZ090Q
					More data for this Ligand-Target Pair
GRM7 (Homo sapiens (Human))	BDBM86213 (CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051) Show SMILES CCOC(=O)C12CC1C(N=O)c1ccccc1O2 Show InChI InChI=1S/C13H13NO4/c1-2-17-12(15)13-7-9(13)11(14-16)8-5-3-4-6-10(8)18-13/h3-6,9,11H,2,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonist potency against cloned Metabotropic glutamate receptor 7 (mGluR-7).				J Med Chem 43: 2609-45 (2000) BindingDB Entry DOI: 10.7270/Q2DZ090Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM86213 (CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051) Show SMILES CCOC(=O)C12CC1C(N=O)c1ccccc1O2 Show InChI InChI=1S/C13H13NO4/c1-2-17-12(15)13-7-9(13)11(14-16)8-5-3-4-6-10(8)18-13/h3-6,9,11H,2,7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Labs Curated by ChEMBL					Assay Description Antagonist activity at human mGlu1b receptor				J Med Chem 50: 2563-8 (2007) Article DOI: 10.1021/jm060950g BindingDB Entry DOI: 10.7270/Q2XS5W7Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM86213 (CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051) Show SMILES CCOC(=O)C12CC1C(N=O)c1ccccc1O2 Show InChI InChI=1S/C13H13NO4/c1-2-17-12(15)13-7-9(13)11(14-16)8-5-3-4-6-10(8)18-13/h3-6,9,11H,2,7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.				Bioorg Med Chem Lett 6: 763-766 (1996) Article DOI: 10.1016/0960-894X(96)00104-7 BindingDB Entry DOI: 10.7270/Q2WS8T7Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM86213 (CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051) Show SMILES CCOC(=O)C12CC1C(N=O)c1ccccc1O2 Show InChI InChI=1S/C13H13NO4/c1-2-17-12(15)13-7-9(13)11(14-16)8-5-3-4-6-10(8)18-13/h3-6,9,11H,2,7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibition of Quisqualate-Induced PI Hydrolysis measured in CHO Metabotropic glutamate receptor 1 Expressing Cells				J Med Chem 43: 4428-36 (2000) BindingDB Entry DOI: 10.7270/Q2988688
					More data for this Ligand-Target Pair