BindingDB PrimarySearch

BDBM86253 CAS_100929-53-1::DAMGO::NSC_104742::US10836728, Compound DAMGO

SMILES: CC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)C(Cc1ccccc1)C(=O)NCCO

InChI Key: InChIKey=HPZJMUBDEAMBFI-UHFFFAOYSA-N

Data: 9 KI 2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 86253
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM86253 (CAS_100929-53-1 \| DAMGO \| NSC_104742 \| US10836728,...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University Curated by PDSP K_i Database									J Pharmacol Exp Ther 307: 947-54 (2003) Article DOI: 10.1124/jpet.103.054775 BindingDB Entry DOI: 10.7270/Q24748FX
Cornell University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM86253 (CAS_100929-53-1 \| DAMGO \| NSC_104742 \| US10836728,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University Curated by PDSP K_i Database									J Pharmacol Exp Ther 307: 947-54 (2003) Article DOI: 10.1124/jpet.103.054775 BindingDB Entry DOI: 10.7270/Q24748FX
Cornell University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM86253 (CAS_100929-53-1 \| DAMGO \| NSC_104742 \| US10836728,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by PDSP K_i Database									Eur J Neurosci 18: 290-5 (2003) Article DOI: 10.1046/j.1460-9568.2003.02744.x BindingDB Entry DOI: 10.7270/Q2P55M37
University of Innsbruck Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM86253 (CAS_100929-53-1 \| DAMGO \| NSC_104742 \| US10836728,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	2.83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University Curated by PDSP K_i Database									J Pharmacol Exp Ther 307: 947-54 (2003) Article DOI: 10.1124/jpet.103.054775 BindingDB Entry DOI: 10.7270/Q24748FX
Cornell University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM86253 (CAS_100929-53-1 \| DAMGO \| NSC_104742 \| US10836728,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Temple University Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 220-30 (2005) Article DOI: 10.1124/jpet.104.073668 BindingDB Entry DOI: 10.7270/Q26T0K6G
Temple University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM86253 (CAS_100929-53-1 \| DAMGO \| NSC_104742 \| US10836728,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by PDSP K_i Database									J Chem Neuroanat 25: 233-47 (2003) Article DOI: 10.1016/s0891-0618(03)00032-2 BindingDB Entry DOI: 10.7270/Q2XP73G2
University of Michigan Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM86253 (CAS_100929-53-1 \| DAMGO \| NSC_104742 \| US10836728,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	213	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University Curated by PDSP K_i Database									J Pharmacol Exp Ther 307: 947-54 (2003) Article DOI: 10.1124/jpet.103.054775 BindingDB Entry DOI: 10.7270/Q24748FX
Cornell University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin/Orphanin FQ, NOP receptor (MOUSE)	BDBM86253 (CAS_100929-53-1 \| DAMGO \| NSC_104742 \| US10836728,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by PDSP K_i Database									Pharmacol Rev 53: 381-415 (2001) BindingDB Entry DOI: 10.7270/Q2QJ7FWB
McGill University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin/Orphanin FQ, NOP receptor (MOUSE)	BDBM86253 (CAS_100929-53-1 \| DAMGO \| NSC_104742 \| US10836728,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by PDSP K_i Database									Pharmacol Rev 53: 381-415 (2001) BindingDB Entry DOI: 10.7270/Q2QJ7FWB
McGill University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Arrestin, beta 1 (Homo sapiens (Human))	BDBM86253 (CAS_100929-53-1 \| DAMGO \| NSC_104742 \| US10836728,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
Mebias Discovery, Inc. US Patent					Assay Description The DISCOVERX PATHHUNTER� β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementa...				US Patent US10836728 (2020)
Mebias Discovery, Inc. US Patent					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM86253 (CAS_100929-53-1 \| DAMGO \| NSC_104742 \| US10836728,...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
Mebias Discovery, Inc. US Patent					Assay Description G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...				US Patent US10836728 (2020)
Mebias Discovery, Inc. US Patent					More data for this Ligand-Target Pair