BDBM86285 CAS_1576::Methcathinone, (-)::NSC_1576

SMILES: CNC(C)C(=O)c1ccccc1

InChI Key: InChIKey=LPLLVINFLBSFRP-UHFFFAOYSA-N

Data: 7 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 86285   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM86285 (CAS_1576 | Methcathinone, (-) | NSC_1576) Show SMILES CNC(C)C(=O)c1ccccc1 Show InChI InChI=1S/C10H13NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,11H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	13.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by PDSP Ki Database									J Pharmacol Exp Ther 307: 138-45 (2003) Article DOI: 10.1124/jpet.103.053975 BindingDB Entry DOI: 10.7270/Q28W3BVJ
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM86285 (CAS_1576 | Methcathinone, (-) | NSC_1576) Show SMILES CNC(C)C(=O)c1ccccc1 Show InChI InChI=1S/C10H13NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,11H,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	14.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by PDSP Ki Database									J Pharmacol Exp Ther 307: 138-45 (2003) Article DOI: 10.1124/jpet.103.053975 BindingDB Entry DOI: 10.7270/Q28W3BVJ
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM86285 (CAS_1576 | Methcathinone, (-) | NSC_1576) Show SMILES CNC(C)C(=O)c1ccccc1 Show InChI InChI=1S/C10H13NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,11H,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	605	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by PDSP Ki Database									J Pharmacol Exp Ther 307: 138-45 (2003) Article DOI: 10.1124/jpet.103.053975 BindingDB Entry DOI: 10.7270/Q28W3BVJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM86285 (CAS_1576 | Methcathinone, (-) | NSC_1576) Show SMILES CNC(C)C(=O)c1ccccc1 Show InChI InChI=1S/C10H13NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,11H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by PDSP Ki Database									J Pharmacol Exp Ther 307: 138-45 (2003) Article DOI: 10.1124/jpet.103.053975 BindingDB Entry DOI: 10.7270/Q28W3BVJ
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM86285 (CAS_1576 | Methcathinone, (-) | NSC_1576) Show SMILES CNC(C)C(=O)c1ccccc1 Show InChI InChI=1S/C10H13NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,11H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by PDSP Ki Database									J Pharmacol Exp Ther 307: 138-45 (2003) Article DOI: 10.1124/jpet.103.053975 BindingDB Entry DOI: 10.7270/Q28W3BVJ
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM86285 (CAS_1576 | Methcathinone, (-) | NSC_1576) Show SMILES CNC(C)C(=O)c1ccccc1 Show InChI InChI=1S/C10H13NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,11H,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by PDSP Ki Database									J Pharmacol Exp Ther 307: 138-45 (2003) Article DOI: 10.1124/jpet.103.053975 BindingDB Entry DOI: 10.7270/Q28W3BVJ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM86285 (CAS_1576 | Methcathinone, (-) | NSC_1576) Show SMILES CNC(C)C(=O)c1ccccc1 Show InChI InChI=1S/C10H13NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,11H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	9.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by PDSP Ki Database									J Pharmacol Exp Ther 307: 138-45 (2003) Article DOI: 10.1124/jpet.103.053975 BindingDB Entry DOI: 10.7270/Q28W3BVJ
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM86285 (CAS_1576 | Methcathinone, (-) | NSC_1576) Show SMILES CNC(C)C(=O)c1ccccc1 Show InChI InChI=1S/C10H13NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,11H,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.86E+3	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Activity at SERT (unknown origin) assessed as release of [3H]HT				J Med Chem 60: 2605-2628 (2017) Article DOI: 10.1021/acs.jmedchem.7b00085 BindingDB Entry DOI: 10.7270/Q2DJ5HWM
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM86285 (CAS_1576 | Methcathinone, (-) | NSC_1576) Show SMILES CNC(C)C(=O)c1ccccc1 Show InChI InChI=1S/C10H13NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,11H,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Human progesterone receptor (hPR) agonist activity expressed in CV-1 cells				J Med Chem 60: 2605-2628 (2017) Article DOI: 10.1021/acs.jmedchem.7b00085 BindingDB Entry DOI: 10.7270/Q2DJ5HWM
					More data for this Ligand-Target Pair