BindingDB PrimarySearch

BDBM86417 5-amino-2-{1-[1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamido]-4-amino(imino)methylamino-(1R)-butylcarboxamido]-2-phenylethylcarboxamido}pentanamide::CHEMBL2371282::Tyr-d-Arg-Phe-Orn-NH2

SMILES: [#7]-[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccc(-[#8])cc1)-[#6](-[#7])=O

InChI Key: InChIKey=LCKZFWNZLABYEW-XQUALCHDSA-N

Data: 4 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 86417
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (MOUSE)	BDBM86417 (5-amino-2-{1-[1-[1-amino-2-(4-hydroxyphenyl)ethylc...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University Curated by PDSP K_i Database									J Pharmacol Exp Ther 307: 947-54 (2003) Article DOI: 10.1124/jpet.103.054775 BindingDB Entry DOI: 10.7270/Q24748FX
Cornell University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM86417 (5-amino-2-{1-[1-[1-amino-2-(4-hydroxyphenyl)ethylc...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity against opioid receptor mu by displacement of radioligand [3H]-DAGO in rat brain membrane				J Med Chem 32: 698-703 (1989) BindingDB Entry DOI: 10.7270/Q29W0DGM
Clinical Research Institute of Montreal Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM86417 (5-amino-2-{1-[1-[1-amino-2-(4-hydroxyphenyl)ethylc...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University Curated by PDSP K_i Database									J Pharmacol Exp Ther 307: 947-54 (2003) Article DOI: 10.1124/jpet.103.054775 BindingDB Entry DOI: 10.7270/Q24748FX
Cornell University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Opioid receptors; mu & delta (Rattus norvegicus (rat))	BDBM86417 (5-amino-2-{1-[1-[1-amino-2-(4-hydroxyphenyl)ethylc...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.29E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity against opioid receptor delta by displacement of radioligand [3H]-DSLET in rat brain membrane				J Med Chem 32: 698-703 (1989) BindingDB Entry DOI: 10.7270/Q29W0DGM
Clinical Research Institute of Montreal Curated by ChEMBL					More data for this Ligand-Target Pair