BDBM86697 4-TrifluoromethylBZT::8-Methyl-3-[phenyl-(4-trifluoromethyl-phenyl)-methoxy]-8-aza-bicyclo[3.2.1]octane::CHEMBL332772

SMILES: CN1C2CCC1CC(C2)OC(c1ccccc1)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=KFYINOIVXGBXKZ-UHFFFAOYSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 86697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86697 (4-TrifluoromethylBZT | 8-Methyl-3-[phenyl-(4-trifl...) Show SMILES CN1C2CCC1CC(C2)OC(c1ccccc1)c1ccc(cc1)C(F)(F)F |THB:9:7:1:3.4| Show InChI InChI=1S/C22H24F3NO/c1-26-18-11-12-19(26)14-20(13-18)27-21(15-5-3-2-4-6-15)16-7-9-17(10-8-16)22(23,24)25/h2-10,18-21H,11-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	541	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by PDSP Ki Database									J Pharmacol Exp Ther 314: 575-83 (2005) Article DOI: 10.1124/jpet.105.085829 BindingDB Entry DOI: 10.7270/Q27M06H6
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86697 (4-TrifluoromethylBZT | 8-Methyl-3-[phenyl-(4-trifl...) Show SMILES CN1C2CCC1CC(C2)OC(c1ccccc1)c1ccc(cc1)C(F)(F)F |THB:9:7:1:3.4| Show InChI InChI=1S/C22H24F3NO/c1-26-18-11-12-19(26)14-20(13-18)27-21(15-5-3-2-4-6-15)16-7-9-17(10-8-16)22(23,24)25/h2-10,18-21H,11-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	635	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse - Intramural Research Program Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 binding to the dopamine transporter in rat caudate putamen tissue.				J Med Chem 42: 3502-9 (1999) Article DOI: 10.1021/jm980701v BindingDB Entry DOI: 10.7270/Q2VD705D
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86697 (4-TrifluoromethylBZT | 8-Methyl-3-[phenyl-(4-trifl...) Show SMILES CN1C2CCC1CC(C2)OC(c1ccccc1)c1ccc(cc1)C(F)(F)F |THB:9:7:1:3.4| Show InChI InChI=1S/C22H24F3NO/c1-26-18-11-12-19(26)14-20(13-18)27-21(15-5-3-2-4-6-15)16-7-9-17(10-8-16)22(23,24)25/h2-10,18-21H,11-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by PDSP Ki Database									J Pharmacol Exp Ther 314: 575-83 (2005) Article DOI: 10.1124/jpet.105.085829 BindingDB Entry DOI: 10.7270/Q27M06H6
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86697 (4-TrifluoromethylBZT | 8-Methyl-3-[phenyl-(4-trifl...) Show SMILES CN1C2CCC1CC(C2)OC(c1ccccc1)c1ccc(cc1)C(F)(F)F |THB:9:7:1:3.4| Show InChI InChI=1S/C22H24F3NO/c1-26-18-11-12-19(26)14-20(13-18)27-21(15-5-3-2-4-6-15)16-7-9-17(10-8-16)22(23,24)25/h2-10,18-21H,11-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse - Intramural Research Program Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine uptake in rat caudate putamen tissue.				J Med Chem 42: 3502-9 (1999) Article DOI: 10.1021/jm980701v BindingDB Entry DOI: 10.7270/Q2VD705D
					More data for this Ligand-Target Pair