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SMILES: COc1cccc(c1)-n1ncc2c(N=NCc3cccc(F)c3)ncnc12

InChI Key: InChIKey=ZJTAYIAUWYSCGQ-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8682   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))		BDBM8682
PNG
((1E)-1-[(3-fluorophenyl)methylidene]-2-[1-(3-metho...)
Show SMILES COc1cccc(c1)-n1ncc2c(N=NCc3cccc(F)c3)ncnc12 |w:13.13|
Show InChI InChI=1S/C19H15FN6O/c1-27-16-7-3-6-15(9-16)26-19-17(11-24-26)18(21-12-22-19)25-23-10-13-4-2-5-14(20)8-13/h2-9,11-12H,10H2,1H3
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MMDB

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Similars
Article
PubMed
n/an/a 7.94n/an/an/an/an/an/a



GlaxoSmithKline



Assay Description
The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...

Bioorg Med Chem Lett 14: 2121-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.036
BindingDB Entry DOI: 10.7270/Q2NV9GF5
More data for this
Ligand-Target Pair