BDBM87179 5-fluoranyl-N-[(2R)-1-(4-oxidanylidene-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)propan-2-yl]-1H-indole-2-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid::5-fluoro-N-[(1R)-2-(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-1-methyl-ethyl]-1H-indole-2-carboxamide;2,2,2-trifluoroacetic acid::5-fluoro-N-[(2R)-1-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)propan-2-yl]-1H-indole-2-carboxamide;2,2,2-trifluoroacetic acid::VU0364735-1::cid_53470042

SMILES: C[C@H](CN1CCC2(CC1)N(CNC2=O)c1ccccc1)NC(=O)c1cc2cc(F)ccc2[nH]1

InChI Key: InChIKey=MWKBJPMDIRQKGV-QGZVFWFLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 87179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM87179 (5-fluoranyl-N-[(2R)-1-(4-oxidanylidene-1-phenyl-1,...) Show SMILES C[C@H](CN1CCC2(CC1)N(CNC2=O)c1ccccc1)NC(=O)c1cc2cc(F)ccc2[nH]1 Show InChI InChI=1S/C25H28FN5O2/c1-17(28-23(32)22-14-18-13-19(26)7-8-21(18)29-22)15-30-11-9-25(10-12-30)24(33)27-16-31(25)20-5-3-2-4-6-20/h2-8,13-14,17,29H,9-12,15-16H2,1H3,(H,27,33)(H,28,32)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Specialized Chemistry Center Curated by PubChem BioAssay					Assay Description Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2NK3CNK
					More data for this Ligand-Target Pair
Phospholipase D2 (PLD2) (Homo sapiens (Human))	BDBM87179 (5-fluoranyl-N-[(2R)-1-(4-oxidanylidene-1-phenyl-1,...) Show SMILES C[C@H](CN1CCC2(CC1)N(CNC2=O)c1ccccc1)NC(=O)c1cc2cc(F)ccc2[nH]1 Show InChI InChI=1S/C25H28FN5O2/c1-17(28-23(32)22-14-18-13-19(26)7-8-21(18)29-22)15-30-11-9-25(10-12-30)24(33)27-16-31(25)20-5-3-2-4-6-20/h2-8,13-14,17,29H,9-12,15-16H2,1H3,(H,27,33)(H,28,32)/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Specialized Chemistry Center Curated by PubChem BioAssay					Assay Description Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q21R6P4V
					More data for this Ligand-Target Pair