BDBM88733 3-(5-chloranyl-2-methoxy-phenyl)-1-[(1-methylindol-3-yl)methyl]-1-(3-morpholin-4-ylpropyl)thiourea::3-(5-chloro-2-methoxy-phenyl)-1-[(1-methylindol-3-yl)methyl]-1-(3-morpholinopropyl)thiourea::3-(5-chloro-2-methoxyphenyl)-1-[(1-methyl-3-indolyl)methyl]-1-[3-(4-morpholinyl)propyl]thiourea::3-(5-chloro-2-methoxyphenyl)-1-[(1-methylindol-3-yl)methyl]-1-(3-morpholin-4-ylpropyl)thiourea::MLS000583931::N'-(5-chloro-2-methoxyphenyl)-N-[(1-methyl-1H-indol-3-yl)methyl]-N-(3-morpholin-4-ylpropyl)thiourea::SMR000206917::cid_12004930

SMILES: COc1ccc(Cl)cc1NC(=S)N(CCCN1CCOCC1)Cc1cn(C)c2ccccc12

InChI Key: InChIKey=SSVSRXVQUKQNCA-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 88733   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
tyrosine-protein phosphatase non-receptor type 5 isoform a (Homo sapiens (Human))	BDBM88733 (3-(5-chloranyl-2-methoxy-phenyl)-1-[(1-methylindol...) Show SMILES COc1ccc(Cl)cc1NC(=S)N(CCCN1CCOCC1)Cc1cn(C)c2ccccc12 Show InChI InChI=1S/C25H31ClN4O2S/c1-28-17-19(21-6-3-4-7-23(21)28)18-30(11-5-10-29-12-14-32-15-13-29)25(33)27-22-16-20(26)8-9-24(22)31-2/h3-4,6-9,16-17H,5,10-15,18H2,1-2H3,(H,27,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2DV1HGT
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM88733 (3-(5-chloranyl-2-methoxy-phenyl)-1-[(1-methylindol...) Show SMILES COc1ccc(Cl)cc1NC(=S)N(CCCN1CCOCC1)Cc1cn(C)c2ccccc12 Show InChI InChI=1S/C25H31ClN4O2S/c1-28-17-19(21-6-3-4-7-23(21)28)18-30(11-5-10-29-12-14-32-15-13-29)25(33)27-22-16-20(26)8-9-24(22)31-2/h3-4,6-9,16-17H,5,10-15,18H2,1-2H3,(H,27,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	754	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2959G44
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM88733 (3-(5-chloranyl-2-methoxy-phenyl)-1-[(1-methylindol...) Show SMILES COc1ccc(Cl)cc1NC(=S)N(CCCN1CCOCC1)Cc1cn(C)c2ccccc12 Show InChI InChI=1S/C25H31ClN4O2S/c1-28-17-19(21-6-3-4-7-23(21)28)18-30(11-5-10-29-12-14-32-15-13-29)25(33)27-22-16-20(26)8-9-24(22)31-2/h3-4,6-9,16-17H,5,10-15,18H2,1-2H3,(H,27,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2FQ9V6B
					More data for this Ligand-Target Pair
tyrosine-protein phosphatase non-receptor type 5 isoform a (Homo sapiens (Human))	BDBM88733 (3-(5-chloranyl-2-methoxy-phenyl)-1-[(1-methylindol...) Show SMILES COc1ccc(Cl)cc1NC(=S)N(CCCN1CCOCC1)Cc1cn(C)c2ccccc12 Show InChI InChI=1S/C25H31ClN4O2S/c1-28-17-19(21-6-3-4-7-23(21)28)18-30(11-5-10-29-12-14-32-15-13-29)25(33)27-22-16-20(26)8-9-24(22)31-2/h3-4,6-9,16-17H,5,10-15,18H2,1-2H3,(H,27,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2KH0KWR
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM88733 (3-(5-chloranyl-2-methoxy-phenyl)-1-[(1-methylindol...) Show SMILES COc1ccc(Cl)cc1NC(=S)N(CCCN1CCOCC1)Cc1cn(C)c2ccccc12 Show InChI InChI=1S/C25H31ClN4O2S/c1-28-17-19(21-6-3-4-7-23(21)28)18-30(11-5-10-29-12-14-32-15-13-29)25(33)27-22-16-20(26)8-9-24(22)31-2/h3-4,6-9,16-17H,5,10-15,18H2,1-2H3,(H,27,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2T43RPN
					More data for this Ligand-Target Pair