BDBM88797 2-[(5E)-5-[4-[2-(3,4-dimethylanilino)-2-keto-ethoxy]-3-methoxy-benzylidene]-4-keto-2-thioxo-thiazolidin-3-yl]acetic acid::2-[(5E)-5-[[4-[2-(3,4-dimethylanilino)-2-oxoethoxy]-3-methoxyphenyl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid::2-[(5E)-5-[[4-[2-(3,4-dimethylanilino)-2-oxoethoxy]-3-methoxyphenyl]methylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]acetic acid::2-[(5E)-5-[[4-[2-[(3,4-dimethylphenyl)amino]-2-oxidanylidene-ethoxy]-3-methoxy-phenyl]methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanoic acid::MLS001034710::SMR000665623::cid_2186383

SMILES: COc1cc(\C=C2\SC(=S)N(CC(O)=O)C2=O)ccc1OCC(=O)Nc1ccc(C)c(C)c1

InChI Key: InChIKey=TWZVFHIQHPMEBF-VXLYETTFSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 88797   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
tyrosine-protein phosphatase non-receptor type 5 isoform a (Homo sapiens (Human))	BDBM88797 (2-[(5E)-5-[4-[2-(3,4-dimethylanilino)-2-keto-ethox...) Show SMILES COc1cc(\C=C2\SC(=S)N(CC(O)=O)C2=O)ccc1OCC(=O)Nc1ccc(C)c(C)c1 Show InChI InChI=1S/C23H22N2O6S2/c1-13-4-6-16(8-14(13)2)24-20(26)12-31-17-7-5-15(9-18(17)30-3)10-19-22(29)25(11-21(27)28)23(32)33-19/h4-10H,11-12H2,1-3H3,(H,24,26)(H,27,28)/b19-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	6.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2DV1HGT
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM88797 (2-[(5E)-5-[4-[2-(3,4-dimethylanilino)-2-keto-ethox...) Show SMILES COc1cc(\C=C2\SC(=S)N(CC(O)=O)C2=O)ccc1OCC(=O)Nc1ccc(C)c(C)c1 Show InChI InChI=1S/C23H22N2O6S2/c1-13-4-6-16(8-14(13)2)24-20(26)12-31-17-7-5-15(9-18(17)30-3)10-19-22(29)25(11-21(27)28)23(32)33-19/h4-10H,11-12H2,1-3H3,(H,24,26)(H,27,28)/b19-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2959G44
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM88797 (2-[(5E)-5-[4-[2-(3,4-dimethylanilino)-2-keto-ethox...) Show SMILES COc1cc(\C=C2\SC(=S)N(CC(O)=O)C2=O)ccc1OCC(=O)Nc1ccc(C)c(C)c1 Show InChI InChI=1S/C23H22N2O6S2/c1-13-4-6-16(8-14(13)2)24-20(26)12-31-17-7-5-15(9-18(17)30-3)10-19-22(29)25(11-21(27)28)23(32)33-19/h4-10H,11-12H2,1-3H3,(H,24,26)(H,27,28)/b19-10+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2FQ9V6B
					More data for this Ligand-Target Pair
tyrosine-protein phosphatase non-receptor type 5 isoform a (Homo sapiens (Human))	BDBM88797 (2-[(5E)-5-[4-[2-(3,4-dimethylanilino)-2-keto-ethox...) Show SMILES COc1cc(\C=C2\SC(=S)N(CC(O)=O)C2=O)ccc1OCC(=O)Nc1ccc(C)c(C)c1 Show InChI InChI=1S/C23H22N2O6S2/c1-13-4-6-16(8-14(13)2)24-20(26)12-31-17-7-5-15(9-18(17)30-3)10-19-22(29)25(11-21(27)28)23(32)33-19/h4-10H,11-12H2,1-3H3,(H,24,26)(H,27,28)/b19-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2KH0KWR
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM88797 (2-[(5E)-5-[4-[2-(3,4-dimethylanilino)-2-keto-ethox...) Show SMILES COc1cc(\C=C2\SC(=S)N(CC(O)=O)C2=O)ccc1OCC(=O)Nc1ccc(C)c(C)c1 Show InChI InChI=1S/C23H22N2O6S2/c1-13-4-6-16(8-14(13)2)24-20(26)12-31-17-7-5-15(9-18(17)30-3)10-19-22(29)25(11-21(27)28)23(32)33-19/h4-10H,11-12H2,1-3H3,(H,24,26)(H,27,28)/b19-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2T43RPN
					More data for this Ligand-Target Pair