BDBM92355 2-Amino-pyrimidine, 18

SMILES: O=S(=O)(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)c1cccc2cnccc12

InChI Key: InChIKey=DXLZWBFEAYELLQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 92355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM92355 (2-Amino-pyrimidine, 18) Show SMILES O=S(=O)(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)c1cccc2cnccc12 Show InChI InChI=1S/C24H18N6O2S/c31-33(32,23-8-1-4-17-15-26-12-9-21(17)23)30-20-7-2-6-19(14-20)28-24-27-13-10-22(29-24)18-5-3-11-25-16-18/h1-16,30H,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universität Dortmund					Assay Description Inhibition of UmGSK3 by kinase inhibitors.				ACS Chem Biol 7: 1257-67 (2012) Article DOI: 10.1021/cb300128b BindingDB Entry DOI: 10.7270/Q29S1PNH
					More data for this Ligand-Target Pair
Glycogen Synthase Kinase 3 (GSK3) (Ustilago maydis (Smut fungus))	BDBM92355 (2-Amino-pyrimidine, 18) Show SMILES O=S(=O)(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)c1cccc2cnccc12 Show InChI InChI=1S/C24H18N6O2S/c31-33(32,23-8-1-4-17-15-26-12-9-21(17)23)30-20-7-2-6-19(14-20)28-24-27-13-10-22(29-24)18-5-3-11-25-16-18/h1-16,30H,(H,27,28,29)	PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universität Dortmund					Assay Description Inhibition of UmGSK3 by kinase inhibitors.				ACS Chem Biol 7: 1257-67 (2012) Article DOI: 10.1021/cb300128b BindingDB Entry DOI: 10.7270/Q29S1PNH
					More data for this Ligand-Target Pair