BDBM9422 CHEMBL126457::N-{2-[1-(cyclopropylmethyl)piperidin-4-yl]ethyl}-N-methylbenzamide hydrochloride::Piperidine Derivative 34

SMILES: CN(CCC1CCN(CC2CC2)CC1)C(=O)c1ccccc1

InChI Key: InChIKey=GFSATERCQIHYAN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 9422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Mus musculus (mouse))	BDBM9422 (CHEMBL126457 | N-{2-[1-(cyclopropylmethyl)piperidi...) Show SMILES CN(CCC1CCN(CC2CC2)CC1)C(=O)c1ccccc1 Show InChI InChI=1S/C19H28N2O/c1-20(19(22)18-5-3-2-4-6-18)12-9-16-10-13-21(14-11-16)15-17-7-8-17/h2-6,16-17H,7-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition against Acetylcholinesterase (AChE)				J Med Chem 39: 380-7 (1996) Article DOI: 10.1021/jm950704x BindingDB Entry DOI: 10.7270/Q25D8T1Q
					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM9422 (CHEMBL126457 | N-{2-[1-(cyclopropylmethyl)piperidi...) Show SMILES CN(CCC1CCN(CC2CC2)CC1)C(=O)c1ccccc1 Show InChI InChI=1S/C19H28N2O/c1-20(19(22)18-5-3-2-4-6-18)12-9-16-10-13-21(14-11-16)15-17-7-8-17/h2-6,16-17H,7-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Laboratories					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. The amount of a yellow substance formed after incubation was d...				J Med Chem 33: 1880-7 (1990) Article DOI: 10.1021/jm00169a008 BindingDB Entry DOI: 10.7270/Q20Z71H2
					More data for this Ligand-Target Pair