BDBM9523 ((pyridin-4-yl)ethyl)pyridine 5::5-{2-[2-(pyridin-4-yl)ethyl]pyridin-3-yl}-N-[3-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-amine

SMILES: FC(F)(F)c1cccc(Nc2nnc(o2)-c2cccnc2CCc2ccncc2)c1

InChI Key: InChIKey=XXGLWBARAGWFCS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 9523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM9523 (((pyridin-4-yl)ethyl)pyridine 5 | 5-{2-[2-(pyridin...) Show SMILES FC(F)(F)c1cccc(Nc2nnc(o2)-c2cccnc2CCc2ccncc2)c1 Show InChI InChI=1S/C21H16F3N5O/c22-21(23,24)15-3-1-4-16(13-15)27-20-29-28-19(30-20)17-5-2-10-26-18(17)7-6-14-8-11-25-12-9-14/h1-5,8-13H,6-7H2,(H,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...				Bioorg Med Chem Lett 16: 1913-9 (2006) Article DOI: 10.1016/j.bmcl.2005.12.090 BindingDB Entry DOI: 10.7270/Q2C827H5
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM9523 (((pyridin-4-yl)ethyl)pyridine 5 | 5-{2-[2-(pyridin...) Show SMILES FC(F)(F)c1cccc(Nc2nnc(o2)-c2cccnc2CCc2ccncc2)c1 Show InChI InChI=1S/C21H16F3N5O/c22-21(23,24)15-3-1-4-16(13-15)27-20-29-28-19(30-20)17-5-2-10-26-18(17)7-6-14-8-11-25-12-9-14/h1-5,8-13H,6-7H2,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	7.5	22
Chemical Diversity, Inc					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...				Bioorg Med Chem Lett 16: 1913-9 (2006) Article DOI: 10.1016/j.bmcl.2005.12.090 BindingDB Entry DOI: 10.7270/Q2C827H5
					More data for this Ligand-Target Pair