BDBM95242 MLS003123272::N-[2-(dimethylamino)ethyl]-4-[3-(4-phenoxyphenyl)-6-imidazo[1,2-a]pyrazinyl]benzamide::N-[2-(dimethylamino)ethyl]-4-[3-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-6-yl]benzamide::SMR001291104::US10688093, Compound BF000334031::cid_49786470

SMILES: CN(C)CCNC(=O)c1ccc(cc1)-c1cn2c(cnc2cn1)-c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=FEHWRQTWEMENGY-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 95242   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ADP-ribosylation factor GTPase-activating protein 1 (Rattus norvegicus)	BDBM95242 (MLS003123272 | N-[2-(dimethylamino)ethyl]-4-[3-(4-...) Show SMILES CN(C)CCNC(=O)c1ccc(cc1)-c1cn2c(cnc2cn1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C29H27N5O2/c1-33(2)17-16-30-29(35)23-10-8-21(9-11-23)26-20-34-27(18-32-28(34)19-31-26)22-12-14-25(15-13-22)36-24-6-4-3-5-7-24/h3-15,18-20H,16-17H2,1-2H3,(H,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>1.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2Q52N82
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM95242 (MLS003123272 | N-[2-(dimethylamino)ethyl]-4-[3-(4-...) Show SMILES CN(C)CCNC(=O)c1ccc(cc1)-c1cn2c(cnc2cn1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C29H27N5O2/c1-33(2)17-16-30-29(35)23-10-8-21(9-11-23)26-20-34-27(18-32-28(34)19-31-26)22-12-14-25(15-13-22)36-24-6-4-3-5-7-24/h3-15,18-20H,16-17H2,1-2H3,(H,30,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	222	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...				US Patent US10688093 (2020)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM95242 (MLS003123272 | N-[2-(dimethylamino)ethyl]-4-[3-(4-...) Show SMILES CN(C)CCNC(=O)c1ccc(cc1)-c1cn2c(cnc2cn1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C29H27N5O2/c1-33(2)17-16-30-29(35)23-10-8-21(9-11-23)26-20-34-27(18-32-28(34)19-31-26)22-12-14-25(15-13-22)36-24-6-4-3-5-7-24/h3-15,18-20H,16-17H2,1-2H3,(H,30,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...				US Patent US10688093 (2020)
					More data for this Ligand-Target Pair