BDBM97540 US8470820, 51

SMILES: O=C(Nc1cc(no1)-c1ccccn1)c1nc(ccc1Nc1cncnc1)C1CC1

InChI Key: InChIKey=ILSADPHUWPIEGH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM97540 (US8470820, 51) Show SMILES O=C(Nc1cc(no1)-c1ccccn1)c1nc(ccc1Nc1cncnc1)C1CC1 Show InChI InChI=1S/C21H17N7O2/c29-21(27-19-9-18(28-30-19)16-3-1-2-8-24-16)20-17(25-14-10-22-12-23-11-14)7-6-15(26-20)13-4-5-13/h1-3,6-13,25H,4-5H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Scintillation proximity assay using human PDE10A.				US Patent US8470820 (2013) BindingDB Entry DOI: 10.7270/Q2J96501
					More data for this Ligand-Target Pair