BindingDB logo
myBDB logout

null

SMILES: Cn1nc(cc1NC(=O)c1nc(ncc1Nc1cncnc1)C1CC1)-c1ccccn1

InChI Key: InChIKey=XMNOUHBPRNBYMP-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97543   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))		BDBM97543
PNG
(US8470820, 54)
Show SMILES Cn1nc(cc1NC(=O)c1nc(ncc1Nc1cncnc1)C1CC1)-c1ccccn1
Show InChI InChI=1S/C21H19N9O/c1-30-18(8-16(29-30)15-4-2-3-7-24-15)27-21(31)19-17(26-14-9-22-12-23-10-14)11-25-20(28-19)13-5-6-13/h2-4,7-13,26H,5-6H2,1H3,(H,27,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 87n/an/an/an/a7.5n/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Scintillation proximity assay using human PDE10A.

US Patent US8470820 (2013)


BindingDB Entry DOI: 10.7270/Q2J96501
More data for this
Ligand-Target Pair