BDBM98016 US8486966, 10
SMILES: CCOc1cc(n[nH]1)-n1cnc2ccc(N[C@@H](C)c3ccc(F)cn3)nc12
InChI Key: InChIKey=TUGCCAPRWDWOQI-NSHDSACASA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM98016 (US8486966, 10) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | 25 |
Astrazeneca AB US Patent | Assay Description JAK2 and Trk A kinase activity was determined by measuring the kinase's ability to phoshorylate synthetic tyrosine residues within a generic poly... | US Patent US8486966 (2013) BindingDB Entry DOI: 10.7270/Q26T0K7X | |||||||||||
More data for this Ligand-Target Pair |