BDBM98026 US8486966, 23

SMILES: CCOc1cc(n[nH]1)-n1cnc2ccc(N[C@@H](CC)c3ccc(F)cn3)nc12

InChI Key: InChIKey=BCTWYUMIUOLGFL-ZDUSSCGKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98026   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM98026 (US8486966, 23) Show SMILES CCOc1cc(n[nH]1)-n1cnc2ccc(N[C@@H](CC)c3ccc(F)cn3)nc12 |r| Show InChI InChI=1S/C19H20FN7O/c1-3-13(14-6-5-12(20)10-21-14)23-16-8-7-15-19(24-16)27(11-22-15)17-9-18(26-25-17)28-4-2/h5-11,13H,3-4H2,1-2H3,(H,23,24)(H,25,26)/t13-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
Astrazeneca AB US Patent					Assay Description JAK2 and Trk A kinase activity was determined by measuring the kinase's ability to phoshorylate synthetic tyrosine residues within a generic poly...				US Patent US8486966 (2013) BindingDB Entry DOI: 10.7270/Q26T0K7X
					More data for this Ligand-Target Pair