BDBM98548 US8492568, 2

SMILES: COc1cccc(CNC(=O)CC2CC3(CCC3)Oc3ccc(Cl)cc23)c1OC1CCCC1

InChI Key: InChIKey=VEUNEPYUFJEENP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98548   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 3 (Homo sapiens (Human))	BDBM98548 (US8492568, 2) Show SMILES COc1cccc(CNC(=O)CC2CC3(CCC3)Oc3ccc(Cl)cc23)c1OC1CCCC1 Show InChI InChI=1S/C27H32ClNO4/c1-31-24-9-4-6-18(26(24)32-21-7-2-3-8-21)17-29-25(30)14-19-16-27(12-5-13-27)33-23-11-10-20(28)15-22(19)23/h4,6,9-11,15,19,21H,2-3,5,7-8,12-14,16-17H2,1H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	725	n/a	n/a	n/a	n/a	n/a	n/a
Glenmark Pharamceuticals S.A. US Patent					Assay Description Calcium uptake assay: The inhibition of TRPV3 receptor activation was followed as inhibition of 2-aminoethoxydiphenylborate (2-APB) induced cellular...				US Patent US8492568 (2013) BindingDB Entry DOI: 10.7270/Q2J38R50
					More data for this Ligand-Target Pair