BDBM98580 4-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino]-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]sulfamoylmethyl]benzoic acid::US8476306, 6.5

SMILES: NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccc(cc2)C(O)=O)cc1

InChI Key: InChIKey=SWRWEBCZNDCUHE-QGZVFWFLSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 98580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen activator urokinase (Rattus norvegicus)	BDBM98580 (4-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...) Show SMILES NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C21H25N5O7S/c22-19(23)15-5-1-13(2-6-15)9-24-18(28)10-25-20(29)17(11-27)26-34(32,33)12-14-3-7-16(8-4-14)21(30)31/h1-8,17,26-27H,9-12H2,(H3,22,23)(H,24,28)(H,25,29)(H,30,31)/t17-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	150	-9.27	n/a	n/a	n/a	n/a	n/a	n/a	24
The Medicines Company US Patent					Assay Description Inhibition constant of the compound against Plasminogen activator urokinase				US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH
					More data for this Ligand-Target Pair
Trypsin (Rattus norvegicus)	BDBM98580 (4-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...) Show SMILES NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C21H25N5O7S/c22-19(23)15-5-1-13(2-6-15)9-24-18(28)10-25-20(29)17(11-27)26-34(32,33)12-14-3-7-16(8-4-14)21(30)31/h1-8,17,26-27H,9-12H2,(H3,22,23)(H,24,28)(H,25,29)(H,30,31)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	480	-8.59	n/a	n/a	n/a	n/a	n/a	n/a	24
The Medicines Company US Patent					Assay Description Inhibition constant of the compound against Trypsin				US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH
					More data for this Ligand-Target Pair
Plasmin (Rattus norvegicus)	BDBM98580 (4-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...) Show SMILES NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C21H25N5O7S/c22-19(23)15-5-1-13(2-6-15)9-24-18(28)10-25-20(29)17(11-27)26-34(32,33)12-14-3-7-16(8-4-14)21(30)31/h1-8,17,26-27H,9-12H2,(H3,22,23)(H,24,28)(H,25,29)(H,30,31)/t17-/m1/s1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.50E+4	-6.05	n/a	n/a	n/a	n/a	n/a	n/a	24
The Medicines Company US Patent					Assay Description Inhibition constant of the compound against Plasmin				US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH
					More data for this Ligand-Target Pair
Thrombin (Rattus norvegicus)	BDBM98580 (4-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...) Show SMILES NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C21H25N5O7S/c22-19(23)15-5-1-13(2-6-15)9-24-18(28)10-25-20(29)17(11-27)26-34(32,33)12-14-3-7-16(8-4-14)21(30)31/h1-8,17,26-27H,9-12H2,(H3,22,23)(H,24,28)(H,25,29)(H,30,31)/t17-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.70E+5	-5.12	n/a	n/a	n/a	n/a	n/a	n/a	24
The Medicines Company US Patent					Assay Description Inhibition constant of the compound against Thrombin				US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH
					More data for this Ligand-Target Pair