BDBM98585 (2R)-N-[(1S)-2-[(4-carbamimidoylphenyl)methylamino]-1-methyl-2-oxo-ethyl]-2-[(4-cyanophenyl)methylsulfonylamino]-3-hydroxy-propanamide::US8476306, 6.10
SMILES: C[C@H](NC(=O)[C@@H](CO)NS(=O)(=O)Cc1ccc(cc1)C#N)C(=O)NCc1ccc(cc1)C(N)=N
InChI Key: InChIKey=UMTXMVBYSMIVTH-IFXJQAMLSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Plasminogen activator urokinase (Rattus norvegicus) | BDBM98585 ((2R)-N-[(1S)-2-[(4-carbamimidoylphenyl)methylamino...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 89 | -9.58 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Plasminogen activator urokinase | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin (Rattus norvegicus) | BDBM98585 ((2R)-N-[(1S)-2-[(4-carbamimidoylphenyl)methylamino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 340 | -8.79 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombin (Rattus norvegicus) | BDBM98585 ((2R)-N-[(1S)-2-[(4-carbamimidoylphenyl)methylamino...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 8.50E+3 | -6.89 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Thrombin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmin (Rattus norvegicus) | BDBM98585 ((2R)-N-[(1S)-2-[(4-carbamimidoylphenyl)methylamino...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.70E+4 | -6.21 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Plasmin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair |