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SMILES: CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#CC(C)(C)O

InChI Key: InChIKey=WUBGDUUMTMFRQN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98605   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 3


(Homo sapiens (Human))		BDBM98605
PNG
(2-amino-1-ethyl-7-[2-(3-hydroxytetrahydrofuran-3-y...)
Show SMILES CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#CC(C)(C)O
Show InChI InChI=1S/C17H20N4O3/c1-5-21-14(18)12(16(23)19-4)13(22)11-7-6-10(20-15(11)21)8-9-17(2,3)24/h6-7,24H,5,18H2,1-4H3,(H,19,23)
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Similars
US Patent
n/an/a 23n/an/an/an/an/a20



Sanofi

US Patent


Assay Description
Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.

US Patent US8470847 (2013)


BindingDB Entry DOI: 10.7270/Q2WD3Z67
More data for this
Ligand-Target Pair