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SMILES: CNC(=O)c1c(N)n(C2CCCCC2)c2nc(ccc2c1=O)C#CC(C)(O)COC

InChI Key: InChIKey=WFUPSNYDUZZHML-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98616   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 3


(Homo sapiens (Human))		BDBM98616
PNG
(2-amino-1-cyclohexyl-7-(3-hydroxy-4-methoxy-3-meth...)
Show SMILES CNC(=O)c1c(N)n(C2CCCCC2)c2nc(ccc2c1=O)C#CC(C)(O)COC
Show InChI InChI=1S/C22H28N4O4/c1-22(29,13-30-3)12-11-14-9-10-16-18(27)17(21(28)24-2)19(23)26(20(16)25-14)15-7-5-4-6-8-15/h9-10,15,29H,4-8,13,23H2,1-3H3,(H,24,28)
PDB

KEGG

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Similars
US Patent
n/an/a 5n/an/an/an/an/a20



Sanofi

US Patent


Assay Description
Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.

US Patent US8470847 (2013)


BindingDB Entry DOI: 10.7270/Q2WD3Z67
More data for this
Ligand-Target Pair