BDBM98633 US8497376, 14

SMILES: CC1(C)CCC(=CC1)c1cc(ccc1NC(=O)c1ncc([nH]1)C#N)C1C[C@@](C)(CO)O[C@@](C)(CO)C1

InChI Key: InChIKey=QELCUZODUVQCJI-KGPDTDBQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (c-Fms) (Mus musculus (Mouse))	BDBM98633 (US8497376, 14) Show SMILES CC1(C)CCC(=CC1)c1cc(ccc1NC(=O)c1ncc([nH]1)C#N)C1C[C@@](C)(CO)O[C@@](C)(CO)C1 |r,c:5| Show InChI InChI=1S/C28H36N4O4/c1-26(2)9-7-18(8-10-26)22-11-19(20-12-27(3,16-33)36-28(4,13-20)17-34)5-6-23(22)32-25(35)24-30-15-21(14-29)31-24/h5-7,11,15,20,33-34H,8-10,12-13,16-17H2,1-4H3,(H,30,31)(H,32,35)/t20?,27-,28+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica N.V. US Patent					Assay Description An autophosphorylation, fluroescence polarization competition immunoassay was used to determine the potency for c-fms inhibition.				US Patent US8497376 (2013) BindingDB Entry DOI: 10.7270/Q2RN36GW
					More data for this Ligand-Target Pair