BDBM99198 US8501708, 18
SMILES: OC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(NC3CCC[C@@H]3OCc3cccc(F)c3)ncnc12
InChI Key: InChIKey=CYHRDMKKFSGMNK-XCUHZOMWSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A1 (A1) (Oryctolagus cuniculus (Rabbit)) | BDBM99198 (US8501708, 18) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 12.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inotek Pharmaceuticals Corporation US Patent | Assay Description The compounds were studied in binding assays to determine selectivity and potency to A1, A2a and A3 adenosine receptors. | US Patent US8501708 (2013) BindingDB Entry DOI: 10.7270/Q2QN65CZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A3 (Oryctolagus cuniculus (rabbit)) | BDBM99198 (US8501708, 18) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inotek Pharmaceuticals Corporation US Patent | Assay Description The compounds were studied in binding assays to determine selectivity and potency to A1, A2a and A3 adenosine receptors. | US Patent US8501708 (2013) BindingDB Entry DOI: 10.7270/Q2QN65CZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine A2a receptor (Oryctolagus cuniculus (rabbit)) | BDBM99198 (US8501708, 18) | PDB MMDB B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 7.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inotek Pharmaceuticals Corporation US Patent | Assay Description The compounds were studied in binding assays to determine selectivity and potency to A1, A2a and A3 adenosine receptors. | US Patent US8501708 (2013) BindingDB Entry DOI: 10.7270/Q2QN65CZ | |||||||||||
More data for this Ligand-Target Pair |