BDBM99215 US8497368, 5

SMILES: C\C(=N/Nc1ccccn1)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1

InChI Key: InChIKey=NYJXSYHUDLNAMK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99215   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM99215 (US8497368, 5) Show SMILES C\C(=N/Nc1ccccn1)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 Show InChI InChI=1S/C23H18FN7/c1-15(28-29-22-6-2-3-9-26-22)20-7-8-23-27-14-18(31(23)30-20)12-17-11-16-5-4-10-25-21(16)13-19(17)24/h2-11,13-15H,12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8497368 (2013) BindingDB Entry DOI: 10.7270/Q2KW5DN7
					More data for this Ligand-Target Pair