BDBM99221 US8497368, 11

SMILES: C\C(=N/N1CC(=O)NC1=O)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1

InChI Key: InChIKey=ZJWZWMFGOYHRIH-RPPGKUMJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99221   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM99221 (US8497368, 11) Show SMILES C\C(=N/N1CC(=O)NC1=O)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 Show InChI InChI=1S/C21H16FN7O2/c1-12(26-28-11-20(30)25-21(28)31)17-4-5-19-24-10-15(29(19)27-17)8-14-7-13-3-2-6-23-18(13)9-16(14)22/h2-7,9-11,30H,8H2,1H3,(H,25,31)/b26-12+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8497368 (2013) BindingDB Entry DOI: 10.7270/Q2KW5DN7
					More data for this Ligand-Target Pair