BDBM99225 US8497368, 15

SMILES: CC(=NNC(=S)NCc1ccccc1)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1

InChI Key: InChIKey=RNPYQHQTIMBRHN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM99225 (US8497368, 15) Show SMILES CC(=NNC(=S)NCc1ccccc1)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 |w:2.2| Show InChI InChI=1S/C26H22FN7S/c1-17(31-32-26(35)30-15-18-6-3-2-4-7-18)23-9-10-25-29-16-21(34(25)33-23)13-20-12-19-8-5-11-28-24(19)14-22(20)27/h2-12,14,16H,13,15H2,1H3,(H2,30,32,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	932	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8497368 (2013) BindingDB Entry DOI: 10.7270/Q2KW5DN7
					More data for this Ligand-Target Pair