BDBM99235 US8497368, 27

SMILES: CC(=NNC(N)=O)c1ccc2ncc(n2n1)C(C)(O)c1cc2cccnc2cc1F

InChI Key: InChIKey=QCPVGCKJHKWSHC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99235   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM99235 (US8497368, 27) Show SMILES CC(=NNC(N)=O)c1ccc2ncc(n2n1)C(C)(O)c1cc2cccnc2cc1F |w:2.2| Show InChI InChI=1S/C20H18FN7O2/c1-11(25-26-19(22)29)15-5-6-18-24-10-17(28(18)27-15)20(2,30)13-8-12-4-3-7-23-16(12)9-14(13)21/h3-10,30H,1-2H3,(H3,22,26,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8497368 (2013) BindingDB Entry DOI: 10.7270/Q2KW5DN7
					More data for this Ligand-Target Pair