BindingDB logo
myBDB logout

null

SMILES: CC(=NNC(N)=O)c1ccc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1

InChI Key: InChIKey=DEUDJJFWDGOBNT-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99241   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99241
PNG
(US8497368, 33)
Show SMILES CC(=NNC(N)=O)c1ccc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1 |w:2.2|
Show InChI InChI=1S/C18H14F2N8O/c1-10(23-26-17(21)29)13-6-7-15-24-25-16(28(15)27-13)18(19,20)12-4-5-14-11(9-12)3-2-8-22-14/h2-9H,1H3,(H3,21,26,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 0.700n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair