BDBM99256 US8497368, 48

SMILES: CN(N=C(C)c1ccc2nnc(n2n1)C(C)(C)c1ccc2ncccc2c1)C(N)=O

InChI Key: InChIKey=PSSKWHGSUXPIKI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM99256 (US8497368, 48) Show SMILES CN(N=C(C)c1ccc2nnc(n2n1)C(C)(C)c1ccc2ncccc2c1)C(N)=O |w:2.1| Show InChI InChI=1S/C21H22N8O/c1-13(26-28(4)20(22)30)16-9-10-18-24-25-19(29(18)27-16)21(2,3)15-7-8-17-14(12-15)6-5-11-23-17/h5-12H,1-4H3,(H2,22,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8497368 (2013) BindingDB Entry DOI: 10.7270/Q2KW5DN7
					More data for this Ligand-Target Pair