BDBM99270 US8497368, 62

SMILES: CNC(=O)N(C)N=C(C)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1

InChI Key: InChIKey=QELDZPVTQQCJAU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM99270 (US8497368, 62) Show SMILES CNC(=O)N(C)N=C(C)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 |w:6.5| Show InChI InChI=1S/C19H19N9O/c1-12(25-27(3)19(29)20-2)16-10-22-17-18(23-16)28(26-24-17)11-13-6-7-15-14(9-13)5-4-8-21-15/h4-10H,11H2,1-3H3,(H,20,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	685	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8497368 (2013) BindingDB Entry DOI: 10.7270/Q2KW5DN7
					More data for this Ligand-Target Pair