BDBM99491 US8501768, 19

SMILES: Fc1ccc(CC(=O)N2C[C@H]3CCN(C(=O)[C@H]3C2)c2ccc(OCC(F)(F)F)cc2)cc1

InChI Key: InChIKey=VUKYNERAKZLTOZ-UZLBHIALSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99491   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (Homo sapiens (Human))	BDBM99491 (US8501768, 19) Show SMILES Fc1ccc(CC(=O)N2C[C@H]3CCN(C(=O)[C@H]3C2)c2ccc(OCC(F)(F)F)cc2)cc1 |r| Show InChI InChI=1S/C23H22F4N2O3/c24-17-3-1-15(2-4-17)11-21(30)28-12-16-9-10-29(22(31)20(16)13-28)18-5-7-19(8-6-18)32-14-23(25,26)27/h1-8,16,20H,9-14H2/t16-,20+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	867	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HSL enzyme activity was measured by a colorimetric assay.				US Patent US8501768 (2013) BindingDB Entry DOI: 10.7270/Q26Q1VW3
					More data for this Ligand-Target Pair