Marvin 2D Structure

Wt: 389.4 BDBM50105654	Wt: 325.8 BDBM50105656	Wt: 381.5 BDBM50105659	Wt: 353.4 BDBM50105662	Wt: 388.8 BDBM50411335
Wt: 374.3 BDBM50422987	Wt: 388.4 BDBM50422989	Wt: 374.3 BDBM50422990	Wt: 362.3 BDBM50422991	Wt: 369.3 BDBM50422996
Wt: 378.8 BDBM50423000	Wt: 358.3 BDBM50423001	Wt: 388.8 BDBM50423002	Wt: 388.4 BDBM50520311	Wt: 374.4 BDBM50520300

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 21 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50423000 (CHEMBL231405) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H](-[#7]-[#6](=O)-c1ccc(o1)-c1cccc(Cl)c1)-[#6](-[#8])=O Show InChI InChI=1S/C17H19ClN4O4/c18-11-4-1-3-10(9-11)13-6-7-14(26-13)15(23)22-12(16(24)25)5-2-8-21-17(19)20/h1,3-4,6-7,9,12H,2,5,8H2,(H,22,23)(H,24,25)(H4,19,20,21)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
UCB Global Chemistry Curated by ChEMBL					Assay Description Inhibition of human C3a receptor expressed on HMC1 cells by SPA assay				Bioorg Med Chem Lett 17: 3258-61 (2007) Article DOI: 10.1016/j.bmcl.2007.04.022 BindingDB Entry DOI: 10.7270/Q2V69KTN
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50423001 (CHEMBL231303) Show SMILES [#6]-c1cccc(c1)-c1ccc(o1)-[#6](=O)-[#7]-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](-[#8])=O Show InChI InChI=1S/C18H22N4O4/c1-11-4-2-5-12(10-11)14-7-8-15(26-14)16(23)22-13(17(24)25)6-3-9-21-18(19)20/h2,4-5,7-8,10,13H,3,6,9H2,1H3,(H,22,23)(H,24,25)(H4,19,20,21)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
UCB Global Chemistry Curated by ChEMBL					Assay Description Inhibition of human C3a receptor expressed on HMC1 cells by SPA assay				Bioorg Med Chem Lett 17: 3258-61 (2007) Article DOI: 10.1016/j.bmcl.2007.04.022 BindingDB Entry DOI: 10.7270/Q2V69KTN
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50422989 (CHEMBL427268) Show SMILES [#6]-[#6]-[#8]-c1cccc(c1)-c1ccc(o1)-[#6](=O)-[#7]-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](-[#8])=O Show InChI InChI=1S/C19H24N4O5/c1-2-27-13-6-3-5-12(11-13)15-8-9-16(28-15)17(24)23-14(18(25)26)7-4-10-22-19(20)21/h3,5-6,8-9,11,14H,2,4,7,10H2,1H3,(H,23,24)(H,25,26)(H4,20,21,22)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
UCB Global Chemistry Curated by ChEMBL					Assay Description Inhibition of human C3a receptor expressed on HMC1 cells by SPA assay				Bioorg Med Chem Lett 17: 3258-61 (2007) Article DOI: 10.1016/j.bmcl.2007.04.022 BindingDB Entry DOI: 10.7270/Q2V69KTN
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50422996 (CHEMBL231404) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H](-[#7]-[#6](=O)-c1ccc(o1)-c1cccc(c1)C#N)-[#6](-[#8])=O Show InChI InChI=1S/C18H19N5O4/c19-10-11-3-1-4-12(9-11)14-6-7-15(27-14)16(24)23-13(17(25)26)5-2-8-22-18(20)21/h1,3-4,6-7,9,13H,2,5,8H2,(H,23,24)(H,25,26)(H4,20,21,22)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
UCB Global Chemistry Curated by ChEMBL					Assay Description Inhibition of human C3a receptor expressed on HMC1 cells by SPA assay				Bioorg Med Chem Lett 17: 3258-61 (2007) Article DOI: 10.1016/j.bmcl.2007.04.022 BindingDB Entry DOI: 10.7270/Q2V69KTN
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50422990 (CHEMBL394538) Show SMILES [#6]-[#8]-c1cccc(c1)-c1ccc(o1)-[#6](=O)-[#7]-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](-[#8])=O Show InChI InChI=1S/C18H22N4O5/c1-26-12-5-2-4-11(10-12)14-7-8-15(27-14)16(23)22-13(17(24)25)6-3-9-21-18(19)20/h2,4-5,7-8,10,13H,3,6,9H2,1H3,(H,22,23)(H,24,25)(H4,19,20,21)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
UCB Global Chemistry Curated by ChEMBL					Assay Description Inhibition of human C3a receptor expressed on HMC1 cells by SPA assay				Bioorg Med Chem Lett 17: 3258-61 (2007) Article DOI: 10.1016/j.bmcl.2007.04.022 BindingDB Entry DOI: 10.7270/Q2V69KTN
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50422991 (CHEMBL389349) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H](-[#7]-[#6](=O)-c1ccc(o1)-c1cccc(F)c1)-[#6](-[#8])=O Show InChI InChI=1S/C17H19FN4O4/c18-11-4-1-3-10(9-11)13-6-7-14(26-13)15(23)22-12(16(24)25)5-2-8-21-17(19)20/h1,3-4,6-7,9,12H,2,5,8H2,(H,22,23)(H,24,25)(H4,19,20,21)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
UCB Global Chemistry Curated by ChEMBL					Assay Description Inhibition of human C3a receptor expressed on HMC1 cells by SPA assay				Bioorg Med Chem Lett 17: 3258-61 (2007) Article DOI: 10.1016/j.bmcl.2007.04.022 BindingDB Entry DOI: 10.7270/Q2V69KTN
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50422987 (CHEMBL394539) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H](-[#7]-[#6](=O)-c1ccc(o1)-c1cccc(-[#6]-[#8])c1)-[#6](-[#8])=O Show InChI InChI=1S/C18H22N4O5/c19-18(20)21-8-2-5-13(17(25)26)22-16(24)15-7-6-14(27-15)12-4-1-3-11(9-12)10-23/h1,3-4,6-7,9,13,23H,2,5,8,10H2,(H,22,24)(H,25,26)(H4,19,20,21)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
UCB Global Chemistry Curated by ChEMBL					Assay Description Inhibition of human C3a receptor expressed on HMC1 cells by SPA assay				Bioorg Med Chem Lett 17: 3258-61 (2007) Article DOI: 10.1016/j.bmcl.2007.04.022 BindingDB Entry DOI: 10.7270/Q2V69KTN
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50423002 (CHEMBL228847) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H](-[#7]-[#6](=O)-c1cccc(c1)-c1cccc(Cl)c1)-[#6](-[#8])=O Show InChI InChI=1S/C19H21ClN4O3/c20-15-7-2-5-13(11-15)12-4-1-6-14(10-12)17(25)24-16(18(26)27)8-3-9-23-19(21)22/h1-2,4-7,10-11,16H,3,8-9H2,(H,24,25)(H,26,27)(H4,21,22,23)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
UCB Global Chemistry Curated by ChEMBL					Assay Description Inhibition of human C3a receptor expressed on HMC1 cells by SPA assay				Bioorg Med Chem Lett 17: 3258-61 (2007) Article DOI: 10.1016/j.bmcl.2007.04.022 BindingDB Entry DOI: 10.7270/Q2V69KTN
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50105662 (1,3-Bis-[(Z)-4-methyl-benzylimino]-2,3-dihydro-1H-...) Show SMILES Cc1ccc(CNC2=N\C(=N/Cc3ccc(C)cc3)c3ccccc23)cc1 |t:7| Show InChI InChI=1S/C24H23N3/c1-17-7-11-19(12-8-17)15-25-23-21-5-3-4-6-22(21)24(27-23)26-16-20-13-9-18(2)10-14-20/h3-14H,15-16H2,1-2H3,(H,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assay				Bioorg Med Chem Lett 11: 2817-20 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VDN
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50105659 (1,3-Bis-[(Z)-2-p-tolyl-ethylimino]-2,3-dihydro-1H-...) Show SMILES Cc1ccc(CCNC2=N\C(=N/CCc3ccc(C)cc3)c3ccccc23)cc1 |t:8| Show InChI InChI=1S/C26H27N3/c1-19-7-11-21(12-8-19)15-17-27-25-23-5-3-4-6-24(23)26(29-25)28-18-16-22-13-9-20(2)10-14-22/h3-14H,15-18H2,1-2H3,(H,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assay				Bioorg Med Chem Lett 11: 2817-20 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VDN
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50105656 (1-[(Z)-2-(4-Chloro-phenyl)-ethylimino]-3-[(Z)-isop...) Show SMILES CC(C)NC1=N\C(=N/CCc2ccc(Cl)cc2)c2ccccc12 |t:4| Show InChI InChI=1S/C19H20ClN3/c1-13(2)22-19-17-6-4-3-5-16(17)18(23-19)21-12-11-14-7-9-15(20)10-8-14/h3-10,13H,11-12H2,1-2H3,(H,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assay				Bioorg Med Chem Lett 11: 2817-20 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VDN
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520311 (CHEMBL4521007) Show SMILES CC(c1ccc(s1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H24N4O3S/c1-12(13-6-3-2-4-7-13)15-9-10-16(27-15)17(24)23-14(18(25)26)8-5-11-22-19(20)21/h2-4,6-7,9-10,12,14H,5,8,11H2,1H3,(H,23,24)(H,25,26)(H4,20,21,22)/t12?,14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520300 (CHEMBL4439168) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(Cc2ccccc2)s1)C(O)=O |r| Show InChI InChI=1S/C18H22N4O3S/c19-18(20)21-10-4-7-14(17(24)25)22-16(23)15-9-8-13(26-15)11-12-5-2-1-3-6-12/h1-3,5-6,8-9,14H,4,7,10-11H2,(H,22,23)(H,24,25)(H4,19,20,21)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520300 (CHEMBL4439168) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(Cc2ccccc2)s1)C(O)=O |r| Show InChI InChI=1S/C18H22N4O3S/c19-18(20)21-10-4-7-14(17(24)25)22-16(23)15-9-8-13(26-15)11-12-5-2-1-3-6-12/h1-3,5-6,8-9,14H,4,7,10-11H2,(H,22,23)(H,24,25)(H4,19,20,21)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520311 (CHEMBL4521007) Show SMILES CC(c1ccc(s1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H24N4O3S/c1-12(13-6-3-2-4-7-13)15-9-10-16(27-15)17(24)23-14(18(25)26)8-5-11-22-19(20)21/h2-4,6-7,9-10,12,14H,5,8,11H2,1H3,(H,23,24)(H,25,26)(H4,20,21,22)/t12?,14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50105654 (1,3-Bis-[(Z)-2-(4-fluoro-phenyl)-ethylimino]-2,3-d...) Show SMILES Fc1ccc(CCNC2=N\C(=N/CCc3ccc(F)cc3)c3ccccc23)cc1 |t:8| Show InChI InChI=1S/C24H21F2N3/c25-19-9-5-17(6-10-19)13-15-27-23-21-3-1-2-4-22(21)24(29-23)28-16-14-18-7-11-20(26)12-8-18/h1-12H,13-16H2,(H,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assay				Bioorg Med Chem Lett 11: 2817-20 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VDN
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50411335 (CHEMBL228846) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H](-[#7]-[#6](=O)-c1ccc(cc1)-c1cccc(Cl)c1)-[#6](-[#8])=O Show InChI InChI=1S/C19H21ClN4O3/c20-15-4-1-3-14(11-15)12-6-8-13(9-7-12)17(25)24-16(18(26)27)5-2-10-23-19(21)22/h1,3-4,6-9,11,16H,2,5,10H2,(H,24,25)(H,26,27)(H4,21,22,23)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
UCB Global Chemistry Curated by ChEMBL					Assay Description Inhibition of human C3a receptor expressed on HMC1 cells by SPA assay				Bioorg Med Chem Lett 17: 3258-61 (2007) Article DOI: 10.1016/j.bmcl.2007.04.022 BindingDB Entry DOI: 10.7270/Q2V69KTN
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520300 (CHEMBL4439168) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(Cc2ccccc2)s1)C(O)=O |r| Show InChI InChI=1S/C18H22N4O3S/c19-18(20)21-10-4-7-14(17(24)25)22-16(23)15-9-8-13(26-15)11-12-5-2-1-3-6-12/h1-3,5-6,8-9,14H,4,7,10-11H2,(H,22,23)(H,24,25)(H4,19,20,21)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at C3a receptor in human MDM cells assessed as induction of intracellular calcium release measured at 1 sec interval for => 200 secs...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520311 (CHEMBL4521007) Show SMILES CC(c1ccc(s1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H24N4O3S/c1-12(13-6-3-2-4-7-13)15-9-10-16(27-15)17(24)23-14(18(25)26)8-5-11-22-19(20)21/h2-4,6-7,9-10,12,14H,5,8,11H2,1H3,(H,23,24)(H,25,26)(H4,20,21,22)/t12?,14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at C3a receptor in human MDM cells assessed as induction of intracellular calcium release measured at 1 sec interval for => 200 secs...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520311 (CHEMBL4521007) Show SMILES CC(c1ccc(s1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H24N4O3S/c1-12(13-6-3-2-4-7-13)15-9-10-16(27-15)17(24)23-14(18(25)26)8-5-11-22-19(20)21/h2-4,6-7,9-10,12,14H,5,8,11H2,1H3,(H,23,24)(H,25,26)(H4,20,21,22)/t12?,14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at C3a receptor in human MDM cells assessed as induction of intracellular calcium release measured at 1 sec interval for => 200 secs...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520300 (CHEMBL4439168) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(Cc2ccccc2)s1)C(O)=O |r| Show InChI InChI=1S/C18H22N4O3S/c19-18(20)21-10-4-7-14(17(24)25)22-16(23)15-9-8-13(26-15)11-12-5-2-1-3-6-12/h1-3,5-6,8-9,14H,4,7,10-11H2,(H,22,23)(H,24,25)(H4,19,20,21)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at C3a receptor in human MDM cells assessed as induction of intracellular calcium release measured at 1 sec interval for => 200 secs...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair