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| Wt: 420.3 BDBM81357  Purchase | Wt: 403.8 BDBM81358  | Wt: 488.3 BDBM81359  Purchase | Wt: 380.8 BDBM81360  Purchase | Wt: 415.8 BDBM81361  |
| Wt: 294.3 BDBM81362  | Wt: 429.8 BDBM50318652  Purchase | Wt: 369.4 BDBM50318653  |
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM50318652 ((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet  | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM50318652 ((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 8.00E+3 | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318652 ((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 9.00E+3 | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318652 ((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of NaMN substrate by malachite gre... | J Med Chem 53: 5229-39 (2010) Article DOI: 10.1021/jm100377f BindingDB Entry DOI: 10.7270/Q2Z89DDT | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318652 ((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of ATP substrate by malachite gree... | J Med Chem 53: 5229-39 (2010) Article DOI: 10.1021/jm100377f BindingDB Entry DOI: 10.7270/Q2Z89DDT | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318652 ((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318653 (3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | 1.80E+4 | n/a | 3.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318653 (3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of NaMN substrate by malachite gre... | J Med Chem 53: 5229-39 (2010) Article DOI: 10.1021/jm100377f BindingDB Entry DOI: 10.7270/Q2Z89DDT | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM50318653 (3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM50318653 (3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 2.50E+4 | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318653 (3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318653 (3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of ATP substrate by malachite gree... | J Med Chem 53: 5229-39 (2010) Article DOI: 10.1021/jm100377f BindingDB Entry DOI: 10.7270/Q2Z89DDT | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM81357 (NadD inhibitor 3_05 | US8785499, 3_05) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM81358 (NadD inhibitor 3_15 | US8785499, 3_15) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM50318652 ((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Maryland, Baltimore; The Board of Regents of the University of Texas System; Sanford-Burnham Medical Research Institute US Patent | Assay Description A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,... | US Patent US8785499 (2014) BindingDB Entry DOI: 10.7270/Q2833QPX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81359 (NadD inhibitor 1_03 | US8785499, 1_03) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81359 (NadD inhibitor 1_03 | US8785499, 1_03) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Maryland, Baltimore; The Board of Regents of the University of Texas System; Sanford-Burnham Medical Research Institute US Patent | Assay Description A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,... | US Patent US8785499 (2014) BindingDB Entry DOI: 10.7270/Q2833QPX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81357 (NadD inhibitor 3_05 | US8785499, 3_05) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81357 (NadD inhibitor 3_05 | US8785499, 3_05) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Maryland, Baltimore; The Board of Regents of the University of Texas System; Sanford-Burnham Medical Research Institute US Patent | Assay Description A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,... | US Patent US8785499 (2014) BindingDB Entry DOI: 10.7270/Q2833QPX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM50318652 ((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of substrate by malachite green re... | J Med Chem 53: 5229-39 (2010) Article DOI: 10.1021/jm100377f BindingDB Entry DOI: 10.7270/Q2Z89DDT | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM81359 (NadD inhibitor 1_03 | US8785499, 1_03) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81358 (NadD inhibitor 3_15 | US8785499, 3_15) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 5.10E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Maryland, Baltimore; The Board of Regents of the University of Texas System; Sanford-Burnham Medical Research Institute US Patent | Assay Description A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,... | US Patent US8785499 (2014) BindingDB Entry DOI: 10.7270/Q2833QPX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81358 (NadD inhibitor 3_15 | US8785499, 3_15) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM81361 (NadD inhibitor 3_23 | US8785499, 3_23) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM50318653 (3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Maryland, Baltimore; The Board of Regents of the University of Texas System; Sanford-Burnham Medical Research Institute US Patent | Assay Description A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,... | US Patent US8785499 (2014) BindingDB Entry DOI: 10.7270/Q2833QPX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM81362 (NadD inhibitor 15_11 | US8785499, 15_11) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81360 (NadD inhibitor 3_17 | US8785499, 3_17) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81360 (NadD inhibitor 3_17 | US8785499, 3_17) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.70E+5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Maryland, Baltimore; The Board of Regents of the University of Texas System; Sanford-Burnham Medical Research Institute US Patent | Assay Description A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,... | US Patent US8785499 (2014) BindingDB Entry DOI: 10.7270/Q2833QPX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81362 (NadD inhibitor 15_11 | US8785499, 15_11) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.91E+5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Maryland, Baltimore; The Board of Regents of the University of Texas System; Sanford-Burnham Medical Research Institute US Patent | Assay Description A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,... | US Patent US8785499 (2014) BindingDB Entry DOI: 10.7270/Q2833QPX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81362 (NadD inhibitor 15_11 | US8785499, 15_11) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.91E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81361 (NadD inhibitor 3_23 | US8785499, 3_23) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinate-nucleotide adenylyltransferase (Escherichia coli) | BDBM81361 (NadD inhibitor 3_23 | US8785499, 3_23) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Maryland, Baltimore; The Board of Regents of the University of Texas System; Sanford-Burnham Medical Research Institute US Patent | Assay Description A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,... | US Patent US8785499 (2014) BindingDB Entry DOI: 10.7270/Q2833QPX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Probable nicotinate-nucleotide adenylyltransferase (Bacillus anthracis) | BDBM81360 (NadD inhibitor 3_17 | US8785499, 3_17) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research | Assay Description The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds. | Chem Biol 16: 849-61 (2009) Article DOI: 10.1016/j.chembiol.2009.07.006 BindingDB Entry DOI: 10.7270/Q2N8787C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
