Compile Data Set for Download or QSAR

Found 25 hits with Last Name = 'amezquita-alves' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565105 (CHEMBL4792974) Show SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc3N(c4ccncc4)C(=O)c4cccnc4Oc3c2)ccc1Cl Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565104 (CHEMBL4788035) Show SMILES O=C(Nc1ccccc1)Nc1ccc2N(c3ccncc3)C(=O)c3cccnc3Oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 19 (Homo sapiens (Human))	BDBM50565105 (CHEMBL4792974) Show SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc3N(c4ccncc4)C(=O)c4cccnc4Oc3c2)ccc1Cl Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK19 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) Show SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1 Show InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565103 (CHEMBL4777657) Show SMILES Nc1cc(ccn1)N1c2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2Oc2ncccc2C1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human))	BDBM50565105 (CHEMBL4792974) Show SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc3N(c4ccncc4)C(=O)c4cccnc4Oc3c2)ccc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DDR1 (unknown origin) expressed in HEK293T cells assessed as reduction in collagen-induced DDR1 autophosphorylation				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human))	BDBM50565105 (CHEMBL4792974) Show SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc3N(c4ccncc4)C(=O)c4cccnc4Oc3c2)ccc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DDR1 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565107 (CHEMBL4800453) Show SMILES Fc1ccccc1CNC(=O)Nc1ccc2N(c3ccncc3)C(=O)c3cccnc3Oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	324	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565117 (CHEMBL4780260) Show SMILES CNC(=O)c1cc(ccn1)N1c2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2Oc2ncccc2C1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	361	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565109 (CHEMBL4796082) Show SMILES O=C(Nc1ccccc1)Nc1ccc2N(c3ccoc3)C(=O)c3cccnc3Oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	593	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565111 (CHEMBL4791801) Show SMILES O=C(Nc1ccccc1)Nc1ccc2N(c3ccncc3)C(=O)c3ccccc3Oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565105 (CHEMBL4792974) Show SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc3N(c4ccncc4)C(=O)c4cccnc4Oc3c2)ccc1Cl Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 in human SW-620 cells assessed as reduction in STAT1 phosphorylation at Ser727 residues measured after 8 hrs				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565110 (CHEMBL4784797) Show SMILES O=C(Nc1ccccc1)Nc1ccc2N(Cc3ccncc3)C(=O)c3cccnc3Oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565112 (CHEMBL4781614) Show SMILES O=C(Nc1ccc2N(c3ccncc3)C(=O)c3cccnc3Oc2c1)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565113 (CHEMBL4782031) Show SMILES O=C(Cc1ccccc1)Nc1ccc2N(c3ccncc3)C(=O)c3cccnc3Oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565108 (CHEMBL4786534) Show SMILES O=C(Nc1ccccc1)Nc1ccc2N(c3cccnc3)C(=O)c3cccnc3Oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565106 (CHEMBL4784034) Show SMILES CCCNC(=O)Nc1ccc2N(c3ccncc3)C(=O)c3cccnc3Oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565115 (CHEMBL4794940) Show SMILES CC(C)(O)C(=O)Nc1ccc2N(c3ccncc3)C(=O)c3cccnc3Oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM50565105 (CHEMBL4792974) Show SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc3N(c4ccncc4)C(=O)c4cccnc4Oc3c2)ccc1Cl Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK7 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK4 (Homo sapiens (Human))	BDBM50565105 (CHEMBL4792974) Show SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc3N(c4ccncc4)C(=O)c4cccnc4Oc3c2)ccc1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CLK4 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565103 (CHEMBL4777657) Show SMILES Nc1cc(ccn1)N1c2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2Oc2ncccc2C1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 in human SW-620 cells assessed as reduction in STAT1 phosphorylation at Ser727 residues measured after 8 hrs				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565104 (CHEMBL4788035) Show SMILES O=C(Nc1ccccc1)Nc1ccc2N(c3ccncc3)C(=O)c3cccnc3Oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 in human SW-620 cells assessed as reduction in STAT1 phosphorylation at Ser727 residues measured after 8 hrs				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565114 (CHEMBL4786883) Show SMILES CC(O)(C(=O)Nc1ccc2N(c3ccncc3)C(=O)c3cccnc3Oc2c1)C(F)(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565116 (CHEMBL4795034) Show SMILES O=C(Nc1ccc2N(c3ccncc3)C(=O)c3cccnc3Oc2c1)S(=O)(=O)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) Show SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1 Show InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 in human SW-620 cells assessed as reduction in STAT1 phosphorylation at Ser727 residues measured after 8 hrs				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair				3D Structure (crystal)