Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 8' and Ligand = 'BDBM50565104'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565104 (CHEMBL4788035) Show SMILES O=C(Nc1ccccc1)Nc1ccc2N(c3ccncc3)C(=O)c3cccnc3Oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50565104 (CHEMBL4788035) Show SMILES O=C(Nc1ccccc1)Nc1ccc2N(c3ccncc3)C(=O)c3cccnc3Oc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8 in human SW-620 cells assessed as reduction in STAT1 phosphorylation at Ser727 residues measured after 8 hrs				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112443 BindingDB Entry DOI: 10.7270/Q2TF023Q
					More data for this Ligand-Target Pair