Found 254 hits with Last Name = 'doty' and Initial = 'a' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567132
![PNG](/data/jpeg/tenK5056/BindingDB_50567132.png) (CHEMBL4863767)Show SMILES Fc1ccc(NC(=O)C2(CCC2)C2CCC3C(CCCN3c3ccnc(n3)C(F)(F)F)C2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human whole blood assessed as unbound concentration |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567128
![PNG](/data/jpeg/tenK5056/BindingDB_50567128.png) (CHEMBL4855797)Show SMILES C[C@H](C1CCC2C(CCCN2C(=O)c2cccc(Cl)c2)C1)C(=O)Nc1ccc(F)cc1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human whole blood assessed as unbound concentration |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567131
![PNG](/data/jpeg/tenK5056/BindingDB_50567131.png) (CHEMBL4848630)Show SMILES Cc1nccc(n1)N1CCCC2CC(CCC12)C1(CCC1)C(=O)Nc1ccc(F)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human whole blood assessed as unbound concentration |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50568395
![PNG](/data/jpeg/tenK5056/BindingDB_50568395.png) (CHEMBL4848098)Show SMILES Clc1ccc(NC(=O)C2(CCC2)c2ccc3N(CCc3n2)c2ccccn2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human IDO1 assessed as unbound compound concentration by human whole blood assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128214 BindingDB Entry DOI: 10.7270/Q29K4G0K |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50568383
![PNG](/data/jpeg/tenK5056/BindingDB_50568383.png) (CHEMBL4872023)Show SMILES Fc1ccc(NC(=O)C2(CCC2)c2ccc3N(CCc3c2)C(=O)OC2CC2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human IDO1 assessed as unbound compound concentration by human whole blood assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128214 BindingDB Entry DOI: 10.7270/Q29K4G0K |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50543295
![PNG](/data/jpeg/tenK5054/BindingDB_50543295.png) (CHEMBL4642946)Show SMILES C[C@H](C(=O)Nc1ccc(Cl)cc1)C12CC(C1)(C2)NC(=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C21H20Cl2N2O2/c1-13(18(26)24-17-7-5-15(22)6-8-17)20-10-21(11-20,12-20)25-19(27)14-3-2-4-16(23)9-14/h2-9,13H,10-12H2,1H3,(H,24,26)(H,25,27)/t13-,20?,21?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Inc.
Curated by ChEMBL
| Assay Description Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-tryptophan as substrate incubated for 48 hrs by fluorescence assay |
ACS Med Chem Lett 11: 1548-1554 (2020)
Article DOI: 10.1021/acsmedchemlett.0c00195 BindingDB Entry DOI: 10.7270/Q2RB786J |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50568397
![PNG](/data/jpeg/tenK5056/BindingDB_50568397.png) (CHEMBL4869600)Show SMILES Clc1ccc(cc1)C(=O)NC1(CCC1)c1ccc2N(CCc2n1)C(=O)OC1CC1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.630 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human IDO1 assessed as unbound compound concentration by human whole blood assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128214 BindingDB Entry DOI: 10.7270/Q29K4G0K |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567134
![PNG](/data/jpeg/tenK5056/BindingDB_50567134.png) (CHEMBL4848366)Show SMILES CC(N1CCC2C(CCCN2C(=O)OC2CC2)C1)C(=O)Nc1ccc(Cl)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.730 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human whole blood assessed as unbound concentration |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50552941
![PNG](/data/jpeg/tenK5055/BindingDB_50552941.png) (CHEMBL4764710)Show SMILES C[C@@H](NC(=O)c1ccc(F)cc1)c1ccc2N(CCCc2n1)C(=O)OC1CCC1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as reduction in kynurenine production using L-Tryptophan as substrate incubated ... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00525 BindingDB Entry DOI: 10.7270/Q20G3PS5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50568391
![PNG](/data/jpeg/tenK5056/BindingDB_50568391.png) (CHEMBL4855740)Show SMILES Fc1ccc(NC(=O)C2(CCC2)c2ccc3N(CCc3n2)C(=O)c2cccc(Cl)c2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.840 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human IDO1 assessed as unbound compound concentration by human whole blood assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128214 BindingDB Entry DOI: 10.7270/Q29K4G0K |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567130
![PNG](/data/jpeg/tenK5056/BindingDB_50567130.png) (CHEMBL4858599)Show SMILES Fc1ccc(NC(=O)C2(CCC2)C2CCC3C(CCCN3C(=O)C3CC3)C2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.860 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human whole blood assessed as unbound concentration |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567129
![PNG](/data/jpeg/tenK5056/BindingDB_50567129.png) (CHEMBL4849622)Show SMILES Fc1ccc(NC(=O)C2(CCC2)C2CCC3C(CCCN3C(=O)c3cccc(Cl)c3)C2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.980 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human whole blood assessed as unbound concentration |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567128
![PNG](/data/jpeg/tenK5056/BindingDB_50567128.png) (CHEMBL4855797)Show SMILES C[C@H](C1CCC2C(CCCN2C(=O)c2cccc(Cl)c2)C1)C(=O)Nc1ccc(F)cc1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567128
![PNG](/data/jpeg/tenK5056/BindingDB_50567128.png) (CHEMBL4855797)Show SMILES C[C@H](C1CCC2C(CCCN2C(=O)c2cccc(Cl)c2)C1)C(=O)Nc1ccc(F)cc1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50568383
![PNG](/data/jpeg/tenK5056/BindingDB_50568383.png) (CHEMBL4872023)Show SMILES Fc1ccc(NC(=O)C2(CCC2)c2ccc3N(CCc3c2)C(=O)OC2CC2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human IDO1 in human Hela cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128214 BindingDB Entry DOI: 10.7270/Q29K4G0K |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50552934
![PNG](/data/jpeg/tenK5055/BindingDB_50552934.png) (CHEMBL4744727)Show SMILES C[C@@H](NC(=O)c1ccc(F)cc1)c1ccc2N(CCCc2n1)C(=O)c1cccc(Cl)c1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as reduction in kynurenine production using L-Tryptophan as substrate incubated ... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00525 BindingDB Entry DOI: 10.7270/Q20G3PS5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567130
![PNG](/data/jpeg/tenK5056/BindingDB_50567130.png) (CHEMBL4858599)Show SMILES Fc1ccc(NC(=O)C2(CCC2)C2CCC3C(CCCN3C(=O)C3CC3)C2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50568387
![PNG](/data/jpeg/tenK5056/BindingDB_50568387.png) (CHEMBL4875994)Show SMILES Clc1ccc(NC(=O)C2(CCC2)c2ccc3N(CCc3c2)c2ccccn2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human IDO1 in human Hela cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128214 BindingDB Entry DOI: 10.7270/Q29K4G0K |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50552931
![PNG](/data/jpeg/tenK5055/BindingDB_50552931.png) (CHEMBL4755227)Show SMILES C[C@@H](NC(=O)c1ccc(Cl)cc1)c1ccc2N(CCCc2n1)C(=O)c1cccc(Cl)c1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as reduction in kynurenine production using L-Tryptophan as substrate incubated ... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00525 BindingDB Entry DOI: 10.7270/Q20G3PS5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567131
![PNG](/data/jpeg/tenK5056/BindingDB_50567131.png) (CHEMBL4848630)Show SMILES Cc1nccc(n1)N1CCCC2CC(CCC12)C1(CCC1)C(=O)Nc1ccc(F)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567131
![PNG](/data/jpeg/tenK5056/BindingDB_50567131.png) (CHEMBL4848630)Show SMILES Cc1nccc(n1)N1CCCC2CC(CCC12)C1(CCC1)C(=O)Nc1ccc(F)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50538499
![PNG](/data/jpeg/tenK5053/BindingDB_50538499.png) (CHEMBL4638223)Show SMILES Fc1ccc(NC(=O)C2(CCC2)c2ccc(NC(=O)c3cccc(Cl)c3)cc2)cc1 Show InChI InChI=1S/C24H20ClFN2O2/c25-18-4-1-3-16(15-18)22(29)27-20-9-5-17(6-10-20)24(13-2-14-24)23(30)28-21-11-7-19(26)8-12-21/h1,3-12,15H,2,13-14H2,(H,27,29)(H,28,30) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Inc.
Curated by ChEMBL
| Assay Description Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-tryptophan as substrate incubated for 48 hrs by fluorescence assay |
ACS Med Chem Lett 11: 1548-1554 (2020)
Article DOI: 10.1021/acsmedchemlett.0c00195 BindingDB Entry DOI: 10.7270/Q2RB786J |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50552948
![PNG](/data/jpeg/tenK5055/BindingDB_50552948.png) (CHEMBL4779920)Show SMILES C[C@@H](NC(=O)c1ccc(F)cc1)c1ccc2N(CCCc2n1)c1ccncn1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as reduction in kynurenine production using L-Tryptophan as substrate incubated ... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00525 BindingDB Entry DOI: 10.7270/Q20G3PS5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50552950
![PNG](/data/jpeg/tenK5055/BindingDB_50552950.png) (CHEMBL4783395)Show SMILES C[C@@H](NC(=O)c1ccc(F)cc1)c1ccc2N(CCCc2n1)c1ccnc(n1)C(F)(F)F |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as reduction in kynurenine production using L-Tryptophan as substrate incubated ... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00525 BindingDB Entry DOI: 10.7270/Q20G3PS5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567128
![PNG](/data/jpeg/tenK5056/BindingDB_50567128.png) (CHEMBL4855797)Show SMILES C[C@H](C1CCC2C(CCCN2C(=O)c2cccc(Cl)c2)C1)C(=O)Nc1ccc(F)cc1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567132
![PNG](/data/jpeg/tenK5056/BindingDB_50567132.png) (CHEMBL4863767)Show SMILES Fc1ccc(NC(=O)C2(CCC2)C2CCC3C(CCCN3c3ccnc(n3)C(F)(F)F)C2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567134
![PNG](/data/jpeg/tenK5056/BindingDB_50567134.png) (CHEMBL4848366)Show SMILES CC(N1CCC2C(CCCN2C(=O)OC2CC2)C1)C(=O)Nc1ccc(Cl)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50543291
![PNG](/data/jpeg/tenK5054/BindingDB_50543291.png) (CHEMBL4644751)Show SMILES C[C@H](C(=O)Nc1ccc(F)cc1)C12CC(C1)(C2)NC(=O)c1ccc(F)c(F)c1 |r| Show InChI InChI=1S/C21H19F3N2O2/c1-12(18(27)25-15-5-3-14(22)4-6-15)20-9-21(10-20,11-20)26-19(28)13-2-7-16(23)17(24)8-13/h2-8,12H,9-11H2,1H3,(H,25,27)(H,26,28)/t12-,20?,21?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Inc.
Curated by ChEMBL
| Assay Description Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-tryptophan as substrate incubated for 48 hrs by fluorescence assay |
ACS Med Chem Lett 11: 1548-1554 (2020)
Article DOI: 10.1021/acsmedchemlett.0c00195 BindingDB Entry DOI: 10.7270/Q2RB786J |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567128
![PNG](/data/jpeg/tenK5056/BindingDB_50567128.png) (CHEMBL4855797)Show SMILES C[C@H](C1CCC2C(CCCN2C(=O)c2cccc(Cl)c2)C1)C(=O)Nc1ccc(F)cc1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567132
![PNG](/data/jpeg/tenK5056/BindingDB_50567132.png) (CHEMBL4863767)Show SMILES Fc1ccc(NC(=O)C2(CCC2)C2CCC3C(CCCN3c3ccnc(n3)C(F)(F)F)C2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567132
![PNG](/data/jpeg/tenK5056/BindingDB_50567132.png) (CHEMBL4863767)Show SMILES Fc1ccc(NC(=O)C2(CCC2)C2CCC3C(CCCN3c3ccnc(n3)C(F)(F)F)C2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50568389
![PNG](/data/jpeg/tenK5056/BindingDB_50568389.png) (CHEMBL4865753)Show SMILES Clc1ccc(NC(=O)C2(CCC2)c2ccc3N(CCc3n2)C(=O)OC2CC2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human IDO1 in human Hela cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128214 BindingDB Entry DOI: 10.7270/Q29K4G0K |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50543297
![PNG](/data/jpeg/tenK5054/BindingDB_50543297.png) (CHEMBL4648765)Show SMILES C[C@H](C(=O)Nc1ccc(F)cc1)C12CC(C1)(C2)NC(=O)c1ccc(F)c(Cl)c1 |r| Show InChI InChI=1S/C21H19ClF2N2O2/c1-12(18(27)25-15-5-3-14(23)4-6-15)20-9-21(10-20,11-20)26-19(28)13-2-7-17(24)16(22)8-13/h2-8,12H,9-11H2,1H3,(H,25,27)(H,26,28)/t12-,20?,21?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Inc.
Curated by ChEMBL
| Assay Description Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-tryptophan as substrate incubated for 48 hrs by fluorescence assay |
ACS Med Chem Lett 11: 1548-1554 (2020)
Article DOI: 10.1021/acsmedchemlett.0c00195 BindingDB Entry DOI: 10.7270/Q2RB786J |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50543298
![PNG](/data/jpeg/tenK5054/BindingDB_50543298.png) (CHEMBL4647172)Show SMILES C[C@H](C(=O)Nc1ccc(F)cc1)C12CC(C1)(C2)NC(=O)c1cc(F)cc(Cl)c1 |r| Show InChI InChI=1S/C21H19ClF2N2O2/c1-12(18(27)25-17-4-2-15(23)3-5-17)20-9-21(10-20,11-20)26-19(28)13-6-14(22)8-16(24)7-13/h2-8,12H,9-11H2,1H3,(H,25,27)(H,26,28)/t12-,20?,21?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Inc.
Curated by ChEMBL
| Assay Description Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-tryptophan as substrate incubated for 48 hrs by fluorescence assay |
ACS Med Chem Lett 11: 1548-1554 (2020)
Article DOI: 10.1021/acsmedchemlett.0c00195 BindingDB Entry DOI: 10.7270/Q2RB786J |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50568395
![PNG](/data/jpeg/tenK5056/BindingDB_50568395.png) (CHEMBL4848098)Show SMILES Clc1ccc(NC(=O)C2(CCC2)c2ccc3N(CCc3n2)c2ccccn2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human IDO1 in human Hela cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128214 BindingDB Entry DOI: 10.7270/Q29K4G0K |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567129
![PNG](/data/jpeg/tenK5056/BindingDB_50567129.png) (CHEMBL4849622)Show SMILES Fc1ccc(NC(=O)C2(CCC2)C2CCC3C(CCCN3C(=O)c3cccc(Cl)c3)C2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567129
![PNG](/data/jpeg/tenK5056/BindingDB_50567129.png) (CHEMBL4849622)Show SMILES Fc1ccc(NC(=O)C2(CCC2)C2CCC3C(CCCN3C(=O)c3cccc(Cl)c3)C2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50552940
![PNG](/data/jpeg/tenK5055/BindingDB_50552940.png) (CHEMBL4749009)Show SMILES C[C@@H](NC(=O)c1ccc(F)cc1)c1ccc2N(CCCc2n1)C(=O)OC1CC1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as reduction in kynurenine production using L-Tryptophan as substrate incubated ... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00525 BindingDB Entry DOI: 10.7270/Q20G3PS5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567132
![PNG](/data/jpeg/tenK5056/BindingDB_50567132.png) (CHEMBL4863767)Show SMILES Fc1ccc(NC(=O)C2(CCC2)C2CCC3C(CCCN3c3ccnc(n3)C(F)(F)F)C2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50568388
![PNG](/data/jpeg/tenK5056/BindingDB_50568388.png) (CHEMBL4864878)Show SMILES Fc1ccc(NC(=O)C2(CCC2)c2ccc3N(CCc3n2)C(=O)OC2CC2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human IDO1 in human Hela cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128214 BindingDB Entry DOI: 10.7270/Q29K4G0K |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50285416
![PNG](/data/jpeg/tenK5028/BindingDB_50285416.png) (CHEMBL4161733)Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@@H](C)C(=O)Nc1ccc(Cl)cc1 |r,wU:18.21,1.0,wD:4.7,(66.16,-9.22,;66.17,-7.68,;66.16,-6.15,;67.5,-5.38,;68.84,-6.15,;68.83,-7.69,;67.5,-8.46,;70.18,-5.39,;71.5,-6.16,;72.84,-5.4,;72.84,-3.85,;71.5,-3.08,;71.5,-1.55,;70.17,-.79,;68.84,-1.56,;67.5,-.8,;68.85,-3.09,;70.18,-3.85,;64.83,-8.46,;64.84,-10,;63.5,-7.69,;63.49,-6.14,;62.16,-8.46,;60.83,-7.69,;59.49,-8.47,;58.15,-7.69,;58.16,-6.14,;56.82,-5.38,;59.49,-5.38,;60.83,-6.14,)| Show InChI InChI=1S/C24H24ClFN2O/c1-15(24(29)28-20-9-6-18(25)7-10-20)16-2-4-17(5-3-16)21-12-13-27-23-11-8-19(26)14-22(21)23/h6-17H,2-5H2,1H3,(H,28,29)/t15-,16-,17+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Inc.
Curated by ChEMBL
| Assay Description Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-tryptophan as substrate incubated for 48 hrs by fluorescence assay |
ACS Med Chem Lett 11: 1548-1554 (2020)
Article DOI: 10.1021/acsmedchemlett.0c00195 BindingDB Entry DOI: 10.7270/Q2RB786J |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50568407
![PNG](/data/jpeg/tenK5056/BindingDB_50568407.png) (CHEMBL4849318)Show SMILES [H][C@@]12CC[C@]1([H])c1cc(ccc1N2C(=O)OC)C1(CC1)NC(=O)c1ccc(F)cc1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human IDO1 in human Hela cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128214 BindingDB Entry DOI: 10.7270/Q29K4G0K |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567135
![PNG](/data/jpeg/tenK5056/BindingDB_50567135.png) (CHEMBL4853448)Show SMILES CC(N1CCC2C(CCCN2c2ccnc(C)n2)C1)C(=O)Nc1ccc(Cl)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50568405
![PNG](/data/jpeg/tenK5056/BindingDB_50568405.png) (CHEMBL4847481)Show SMILES [H][C@@]12C[C@]1([H])c1cc(ccc1N2c1ccnc(C)n1)C1(CC1)NC(=O)c1ccc(F)cc1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human IDO1 in human Hela cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128214 BindingDB Entry DOI: 10.7270/Q29K4G0K |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50567129
![PNG](/data/jpeg/tenK5056/BindingDB_50567129.png) (CHEMBL4849622)Show SMILES Fc1ccc(NC(=O)C2(CCC2)C2CCC3C(CCCN3C(=O)c3cccc(Cl)c3)C2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128314 BindingDB Entry DOI: 10.7270/Q2TT4VP5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50568391
![PNG](/data/jpeg/tenK5056/BindingDB_50568391.png) (CHEMBL4855740)Show SMILES Fc1ccc(NC(=O)C2(CCC2)c2ccc3N(CCc3n2)C(=O)c2cccc(Cl)c2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human IDO1 in human Hela cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128214 BindingDB Entry DOI: 10.7270/Q29K4G0K |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50552937
![PNG](/data/jpeg/tenK5055/BindingDB_50552937.png) (CHEMBL4788473)Show SMILES CCOC(=O)N1CCCc2nc(ccc12)[C@@H](C)NC(=O)c1ccc(F)cc1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as reduction in kynurenine production using L-Tryptophan as substrate incubated ... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00525 BindingDB Entry DOI: 10.7270/Q20G3PS5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50552930
![PNG](/data/jpeg/tenK5055/BindingDB_50552930.png) (CHEMBL4744926)Show SMILES C[C@@H](NC(=O)c1ccc(Cl)cc1)c1ccc2N(CCOc2c1)C(=O)c1cccc(Cl)c1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as reduction in kynurenine production using L-Tryptophan as substrate incubated ... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00525 BindingDB Entry DOI: 10.7270/Q20G3PS5 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50543292
![PNG](/data/jpeg/tenK5054/BindingDB_50543292.png) (CHEMBL4632992)Show SMILES C[C@H](C(=O)Nc1ccc(F)cc1)C12CC(C1)(C2)NC(=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C21H20ClFN2O2/c1-13(18(26)24-17-7-5-16(23)6-8-17)20-10-21(11-20,12-20)25-19(27)14-3-2-4-15(22)9-14/h2-9,13H,10-12H2,1H3,(H,24,26)(H,25,27)/t13-,20?,21?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Inc.
Curated by ChEMBL
| Assay Description Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-tryptophan as substrate incubated for 48 hrs by fluorescence assay |
ACS Med Chem Lett 11: 1548-1554 (2020)
Article DOI: 10.1021/acsmedchemlett.0c00195 BindingDB Entry DOI: 10.7270/Q2RB786J |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50568385
![PNG](/data/jpeg/tenK5056/BindingDB_50568385.png) (CHEMBL4877196)Show SMILES Fc1ccc(NC(=O)C2(CCC2)c2ccc3N(CCc3c2)c2ccccn2)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human IDO1 in human Hela cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128214 BindingDB Entry DOI: 10.7270/Q29K4G0K |
More data for this Ligand-Target Pair | |