Found 445 hits with Last Name = 'moulin' and Initial = 'a' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19331
(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)cc1 |r| Show InChI InChI=1S/C36H39N7O2/c1-45-28-13-10-24(11-14-28)23-43-34(15-12-26-21-38-31-8-4-2-6-29(26)31)41-42-35(43)33(40-36(44)25-16-18-37-19-17-25)20-27-22-39-32-9-5-3-7-30(27)32/h2-11,13-14,21-22,25,33,37-39H,12,15-20,23H2,1H3,(H,40,44)/t33-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-Université Montpellier I
Curated by ChEMBL
| Assay Description
Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cells |
Bioorg Med Chem Lett 18: 164-8 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.113
BindingDB Entry DOI: 10.7270/Q2HM586C |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19331
(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)cc1 |r| Show InChI InChI=1S/C36H39N7O2/c1-45-28-13-10-24(11-14-28)23-43-34(15-12-26-21-38-31-8-4-2-6-29(26)31)41-42-35(43)33(40-36(44)25-16-18-37-19-17-25)20-27-22-39-32-9-5-3-7-30(27)32/h2-11,13-14,21-22,25,33,37-39H,12,15-20,23H2,1H3,(H,40,44)/t33-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.300 | n/a | 3 | n/a | n/a | n/a | n/a |
CNRS
| Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co... |
J Med Chem 50: 5790-5806 (2007)
Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19331
(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)cc1 |r| Show InChI InChI=1S/C36H39N7O2/c1-45-28-13-10-24(11-14-28)23-43-34(15-12-26-21-38-31-8-4-2-6-29(26)31)41-42-35(43)33(40-36(44)25-16-18-37-19-17-25)20-27-22-39-32-9-5-3-7-30(27)32/h2-11,13-14,21-22,25,33,37-39H,12,15-20,23H2,1H3,(H,40,44)/t33-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-Université Montpellier I
Curated by ChEMBL
| Assay Description
Antagonist activity at human GHSR1a receptor expressed in CHO cells assessed as reduction of ghrelin-induced intracellular calcium mobilization |
Bioorg Med Chem Lett 18: 164-8 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.113
BindingDB Entry DOI: 10.7270/Q2HM586C |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19333
(N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-[2-(1...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)c(OC)c1 |r| Show InChI InChI=1S/C37H41N7O3/c1-46-28-13-11-26(34(20-28)47-2)23-44-35(14-12-25-21-39-31-9-5-3-7-29(25)31)42-43-36(44)33(41-37(45)24-15-17-38-18-16-24)19-27-22-40-32-10-6-4-8-30(27)32/h3-11,13,20-22,24,33,38-40H,12,14-19,23H2,1-2H3,(H,41,45)/t33-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.5 | n/a | 0.600 | n/a | n/a | n/a | n/a |
CNRS
| Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co... |
J Med Chem 50: 5790-5806 (2007)
Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19331
(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)cc1 |r| Show InChI InChI=1S/C36H39N7O2/c1-45-28-13-10-24(11-14-28)23-43-34(15-12-26-21-38-31-8-4-2-6-29(26)31)41-42-35(43)33(40-36(44)25-16-18-37-19-17-25)20-27-22-39-32-9-5-3-7-30(27)32/h2-11,13-14,21-22,25,33,37-39H,12,15-20,23H2,1H3,(H,40,44)/t33-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Universités Montpellier 1
Curated by ChEMBL
| Assay Description
Displacement of 125I-His9-ghrelin from human GHSR1a expressed in LLCPK1 cells |
J Med Chem 51: 689-93 (2008)
Article DOI: 10.1021/jm701292s
BindingDB Entry DOI: 10.7270/Q2N0168Z |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19332
(N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)m...)Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)cc1 |r| Show InChI InChI=1S/C34H38N6O2/c1-42-28-14-11-25(12-15-28)23-40-32(16-13-24-7-3-2-4-8-24)38-39-33(40)31(37-34(41)26-17-19-35-20-18-26)21-27-22-36-30-10-6-5-9-29(27)30/h2-12,14-15,22,26,31,35-36H,13,16-21,23H2,1H3,(H,37,41)/t31-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.600 | n/a | 1.60 | n/a | n/a | n/a | n/a |
CNRS
| Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co... |
J Med Chem 50: 5790-5806 (2007)
Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50232281
((R)-N-((4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-t...)Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@H](NC(=O)c2ccccn2)c2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C33H30N6O2/c1-41-25-17-14-24(15-18-25)22-39-30(19-16-23-9-3-2-4-10-23)37-38-32(39)31(36-33(40)29-13-7-8-20-34-29)27-21-35-28-12-6-5-11-26(27)28/h2-15,17-18,20-21,31,35H,16,19,22H2,1H3,(H,36,40)/t31-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Universités Montpellier 1
Curated by ChEMBL
| Assay Description
Displacement of 125I-His9-ghrelin from human GHSR1a expressed in LLCPK1 cells |
J Med Chem 51: 689-93 (2008)
Article DOI: 10.1021/jm701292s
BindingDB Entry DOI: 10.7270/Q2N0168Z |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19334
(N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-(2-ph...)Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)c(OC)c1 |r| Show InChI InChI=1S/C35H40N6O3/c1-43-28-14-13-26(32(21-28)44-2)23-41-33(15-12-24-8-4-3-5-9-24)39-40-34(41)31(38-35(42)25-16-18-36-19-17-25)20-27-22-37-30-11-7-6-10-29(27)30/h3-11,13-14,21-22,25,31,36-37H,12,15-20,23H2,1-2H3,(H,38,42)/t31-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.900 | n/a | 6.10 | n/a | n/a | n/a | n/a |
CNRS
| Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co... |
J Med Chem 50: 5790-5806 (2007)
Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50232297
((R)-N-((4-(2,4-dimethoxybenzyl)-5-phenethyl-4H-1,2...)Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@H](NC(=O)c2ccccn2)c2c[nH]c3ccccc23)c(OC)c1 Show InChI InChI=1S/C34H32N6O3/c1-42-25-17-16-24(30(20-25)43-2)22-40-31(18-15-23-10-4-3-5-11-23)38-39-33(40)32(37-34(41)29-14-8-9-19-35-29)27-21-36-28-13-7-6-12-26(27)28/h3-14,16-17,19-21,32,36H,15,18,22H2,1-2H3,(H,37,41)/t32-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Universités Montpellier 1
Curated by ChEMBL
| Assay Description
Displacement of 125I-His9-ghrelin from human GHSR1a expressed in LLCPK1 cells |
J Med Chem 51: 689-93 (2008)
Article DOI: 10.1021/jm701292s
BindingDB Entry DOI: 10.7270/Q2N0168Z |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50232283
((R)-N-((5-(2-(1H-indol-3-yl)ethyl)-4-(2,4-dimethox...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@H](NC(=O)c2ccccn2)c2c[nH]c3ccccc23)c(OC)c1 Show InChI InChI=1S/C36H33N7O3/c1-45-25-16-14-24(32(19-25)46-2)22-43-33(17-15-23-20-38-29-11-5-3-9-26(23)29)41-42-35(43)34(40-36(44)31-13-7-8-18-37-31)28-21-39-30-12-6-4-10-27(28)30/h3-14,16,18-21,34,38-39H,15,17,22H2,1-2H3,(H,40,44)/t34-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Universités Montpellier 1
Curated by ChEMBL
| Assay Description
Displacement of 125I-His9-ghrelin from human GHSR1a expressed in LLCPK1 cells |
J Med Chem 51: 689-93 (2008)
Article DOI: 10.1021/jm701292s
BindingDB Entry DOI: 10.7270/Q2N0168Z |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50232270
((R)-N-((5-(2-(1H-indol-3-yl)ethyl)-4-(4-methoxyben...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@H](NC(=O)c2ccccn2)c2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C35H31N7O2/c1-44-25-16-13-23(14-17-25)22-42-32(18-15-24-20-37-29-10-4-2-8-26(24)29)40-41-34(42)33(39-35(43)31-12-6-7-19-36-31)28-21-38-30-11-5-3-9-27(28)30/h2-14,16-17,19-21,33,37-38H,15,18,22H2,1H3,(H,39,43)/t33-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Universités Montpellier 1
Curated by ChEMBL
| Assay Description
Displacement of 125I-His9-ghrelin from human GHSR1a expressed in LLCPK1 cells |
J Med Chem 51: 689-93 (2008)
Article DOI: 10.1021/jm701292s
BindingDB Entry DOI: 10.7270/Q2N0168Z |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50227177
((R)-pyridin-2-yl 1-(5-(2-(1H-indol-3-yl)ethyl)-4-(...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)Oc2ccccn2)cc1 Show InChI InChI=1S/C36H33N7O3/c1-45-27-16-13-24(14-17-27)23-43-33(18-15-25-21-38-30-10-4-2-8-28(25)30)41-42-35(43)32(40-36(44)46-34-12-6-7-19-37-34)20-26-22-39-31-11-5-3-9-29(26)31/h2-14,16-17,19,21-22,32,38-39H,15,18,20,23H2,1H3,(H,40,44)/t32-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-Université Montpellier I
Curated by ChEMBL
| Assay Description
Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cells |
Bioorg Med Chem Lett 18: 164-8 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.113
BindingDB Entry DOI: 10.7270/Q2HM586C |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50232266
((R)-N-((4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-t...)Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@H](NC(=O)Cc2ccccn2)c2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C34H32N6O2/c1-42-27-17-14-25(15-18-27)23-40-31(19-16-24-9-3-2-4-10-24)38-39-34(40)33(29-22-36-30-13-6-5-12-28(29)30)37-32(41)21-26-11-7-8-20-35-26/h2-15,17-18,20,22,33,36H,16,19,21,23H2,1H3,(H,37,41)/t33-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universités Montpellier 1
Curated by ChEMBL
| Assay Description
Displacement of 125I-His9-ghrelin from human GHSR1a expressed in LLCPK1 cells |
J Med Chem 51: 689-93 (2008)
Article DOI: 10.1021/jm701292s
BindingDB Entry DOI: 10.7270/Q2N0168Z |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50232295
((R)-N-((4-(2,4-dimethoxybenzyl)-5-phenethyl-4H-1,2...)Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@H](NC(=O)c2cnccn2)c2c[nH]c3ccccc23)c(OC)c1 Show InChI InChI=1S/C33H31N7O3/c1-42-24-14-13-23(29(18-24)43-2)21-40-30(15-12-22-8-4-3-5-9-22)38-39-32(40)31(37-33(41)28-20-34-16-17-35-28)26-19-36-27-11-7-6-10-25(26)27/h3-11,13-14,16-20,31,36H,12,15,21H2,1-2H3,(H,37,41)/t31-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universités Montpellier 1
Curated by ChEMBL
| Assay Description
Displacement of 125I-His9-ghrelin from human GHSR1a expressed in LLCPK1 cells |
J Med Chem 51: 689-93 (2008)
Article DOI: 10.1021/jm701292s
BindingDB Entry DOI: 10.7270/Q2N0168Z |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19312
((2S)-N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2)c(OC)c1 |r| Show InChI InChI=1S/C36H39N7O3/c1-45-26-15-13-24(33(19-26)46-2)22-43-34(16-14-23-20-38-29-10-5-3-8-27(23)29)41-42-35(43)32(40-36(44)31-12-7-17-37-31)18-25-21-39-30-11-6-4-9-28(25)30/h3-6,8-11,13,15,19-21,31-32,37-39H,7,12,14,16-18,22H2,1-2H3,(H,40,44)/t31-,32+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.60 | 11 | n/a | n/a | n/a | 7.3 | 25 |
CNRS
| Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co... |
J Med Chem 50: 5790-5806 (2007)
Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19312
((2S)-N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2)c(OC)c1 |r| Show InChI InChI=1S/C36H39N7O3/c1-45-26-15-13-24(33(19-26)46-2)22-43-34(16-14-23-20-38-29-10-5-3-8-27(23)29)41-42-35(43)32(40-36(44)31-12-7-17-37-31)18-25-21-39-30-11-6-4-9-28(25)30/h3-6,8-11,13,15,19-21,31-32,37-39H,7,12,14,16-18,22H2,1-2H3,(H,40,44)/t31-,32+/m0/s1 | PDB
Reactome pathway
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Universités Montpellier 1
Curated by ChEMBL
| Assay Description
Displacement of 125I-His9-ghrelin from human GHSR1a expressed in LLCPK1 cells |
J Med Chem 51: 689-93 (2008)
Article DOI: 10.1021/jm701292s
BindingDB Entry DOI: 10.7270/Q2N0168Z |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19294
(2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indo...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)cc1 |r| Show InChI InChI=1S/C34H37N7O2/c1-34(2,35)33(42)38-30(18-24-20-37-29-11-7-5-9-27(24)29)32-40-39-31(41(32)21-22-12-15-25(43-3)16-13-22)17-14-23-19-36-28-10-6-4-8-26(23)28/h4-13,15-16,19-20,30,36-37H,14,17-18,21,35H2,1-3H3,(H,38,42)/t30-/m1/s1 | PDB
Reactome pathway
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CNRS-Universités Montpellier I et II
Curated by ChEMBL
| Assay Description
Displacement of [125I-His9]ghrelin from human GHS1a receptor expressed in LLC PK1 cells |
J Med Chem 50: 1939-57 (2007)
Article DOI: 10.1021/jm070024h
BindingDB Entry DOI: 10.7270/Q2251HW6 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19349
(N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)m...)Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCOCC2)cc1 |r| Show InChI InChI=1S/C34H37N5O3/c1-41-28-14-11-25(12-15-28)23-39-32(16-13-24-7-3-2-4-8-24)37-38-33(39)31(36-34(40)26-17-19-42-20-18-26)21-27-22-35-30-10-6-5-9-29(27)30/h2-12,14-15,22,26,31,35H,13,16-21,23H2,1H3,(H,36,40)/t31-/m1/s1 | PDB
Reactome pathway
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CNRS
| Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co... |
J Med Chem 50: 5790-5806 (2007)
Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19294
(2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indo...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)cc1 |r| Show InChI InChI=1S/C34H37N7O2/c1-34(2,35)33(42)38-30(18-24-20-37-29-11-7-5-9-27(24)29)32-40-39-31(41(32)21-22-12-15-25(43-3)16-13-22)17-14-23-19-36-28-10-6-4-8-26(23)28/h4-13,15-16,19-20,30,36-37H,14,17-18,21,35H2,1-3H3,(H,38,42)/t30-/m1/s1 | PDB
Reactome pathway
KEGG
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UniChem
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PubMed
| n/a | n/a | 6 | 4 | n/a | n/a | n/a | 7.3 | 25 |
CNRS
| Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co... |
J Med Chem 50: 5790-5806 (2007)
Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19294
(2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indo...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)cc1 |r| Show InChI InChI=1S/C34H37N7O2/c1-34(2,35)33(42)38-30(18-24-20-37-29-11-7-5-9-27(24)29)32-40-39-31(41(32)21-22-12-15-25(43-3)16-13-22)17-14-23-19-36-28-10-6-4-8-26(23)28/h4-13,15-16,19-20,30,36-37H,14,17-18,21,35H2,1-3H3,(H,38,42)/t30-/m1/s1 | PDB
Reactome pathway
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| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-Université Montpellier I
Curated by ChEMBL
| Assay Description
Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cells |
Bioorg Med Chem Lett 18: 164-8 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.113
BindingDB Entry DOI: 10.7270/Q2HM586C |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19294
(2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indo...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)cc1 |r| Show InChI InChI=1S/C34H37N7O2/c1-34(2,35)33(42)38-30(18-24-20-37-29-11-7-5-9-27(24)29)32-40-39-31(41(32)21-22-12-15-25(43-3)16-13-22)17-14-23-19-36-28-10-6-4-8-26(23)28/h4-13,15-16,19-20,30,36-37H,14,17-18,21,35H2,1-3H3,(H,38,42)/t30-/m1/s1 | PDB
Reactome pathway
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| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Universités Montpellier 1
Curated by ChEMBL
| Assay Description
Displacement of 125I-His9-ghrelin from human GHSR1a expressed in LLCPK1 cells |
J Med Chem 51: 689-93 (2008)
Article DOI: 10.1021/jm701292s
BindingDB Entry DOI: 10.7270/Q2N0168Z |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19318
(N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-[2-(1...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCCNC2)c(OC)c1 |r| Show InChI InChI=1S/C37H41N7O3/c1-46-28-15-13-26(34(19-28)47-2)23-44-35(16-14-24-21-39-31-11-5-3-9-29(24)31)42-43-36(44)33(41-37(45)25-8-7-17-38-20-25)18-27-22-40-32-12-6-4-10-30(27)32/h3-6,9-13,15,19,21-22,25,33,38-40H,7-8,14,16-18,20,23H2,1-2H3,(H,41,45)/t25?,33-/m1/s1 | PDB
Reactome pathway
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| n/a | n/a | 6.5 | n/a | 5.30 | n/a | n/a | 7.3 | 25 |
CNRS
| Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co... |
J Med Chem 50: 5790-5806 (2007)
Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19323
((3R)-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphe...)Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCNC2)cc1 |r| Show InChI InChI=1S/C34H38N6O2/c1-42-28-16-13-25(14-17-28)23-40-32(18-15-24-8-3-2-4-9-24)38-39-33(40)31(37-34(41)26-10-7-19-35-21-26)20-27-22-36-30-12-6-5-11-29(27)30/h2-6,8-9,11-14,16-17,22,26,31,35-36H,7,10,15,18-21,23H2,1H3,(H,37,41)/t26-,31-/m1/s1 | PDB
Reactome pathway
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| n/a | n/a | 7 | n/a | 36 | n/a | n/a | n/a | n/a |
CNRS
| Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co... |
J Med Chem 50: 5790-5806 (2007)
Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50227171
((S)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-methoxyb...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)cc1 Show InChI InChI=1S/C36H39N7O2/c1-45-28-13-10-24(11-14-28)23-43-34(15-12-26-21-38-31-8-4-2-6-29(26)31)41-42-35(43)33(40-36(44)25-16-18-37-19-17-25)20-27-22-39-32-9-5-3-7-30(27)32/h2-11,13-14,21-22,25,33,37-39H,12,15-20,23H2,1H3,(H,40,44)/t33-/m0/s1 | PDB
Reactome pathway
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| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-Université Montpellier I
Curated by ChEMBL
| Assay Description
Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cells |
Bioorg Med Chem Lett 18: 164-8 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.113
BindingDB Entry DOI: 10.7270/Q2HM586C |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50232274
((R)-N-((5-(2-(1H-indol-3-yl)ethyl)-4-(4-methoxyben...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@H](NC(=O)Cc2ccccn2)c2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C36H33N7O2/c1-45-27-16-13-24(14-17-27)23-43-33(18-15-25-21-38-31-11-4-2-9-28(25)31)41-42-36(43)35(30-22-39-32-12-5-3-10-29(30)32)40-34(44)20-26-8-6-7-19-37-26/h2-14,16-17,19,21-22,35,38-39H,15,18,20,23H2,1H3,(H,40,44)/t35-/m1/s1 | PDB
Reactome pathway
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| n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Universités Montpellier 1
Curated by ChEMBL
| Assay Description
Displacement of 125I-His9-ghrelin from human GHSR1a expressed in LLCPK1 cells |
J Med Chem 51: 689-93 (2008)
Article DOI: 10.1021/jm701292s
BindingDB Entry DOI: 10.7270/Q2N0168Z |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50227180
((R)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-methoxyb...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccccn2)cc1 Show InChI InChI=1S/C36H33N7O2/c1-45-27-16-13-24(14-17-27)23-43-34(18-15-25-21-38-30-10-4-2-8-28(25)30)41-42-35(43)33(40-36(44)32-12-6-7-19-37-32)20-26-22-39-31-11-5-3-9-29(26)31/h2-14,16-17,19,21-22,33,38-39H,15,18,20,23H2,1H3,(H,40,44)/t33-/m1/s1 | PDB
Reactome pathway
KEGG
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| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-Université Montpellier I
Curated by ChEMBL
| Assay Description
Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cells |
Bioorg Med Chem Lett 18: 164-8 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.113
BindingDB Entry DOI: 10.7270/Q2HM586C |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19308
((2S)-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2)cc1 |r| Show InChI InChI=1S/C35H37N7O2/c1-44-26-15-12-23(13-16-26)22-42-33(17-14-24-20-37-29-9-4-2-7-27(24)29)40-41-34(42)32(39-35(43)31-11-6-18-36-31)19-25-21-38-30-10-5-3-8-28(25)30/h2-5,7-10,12-13,15-16,20-21,31-32,36-38H,6,11,14,17-19,22H2,1H3,(H,39,43)/t31-,32+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
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AffyNet
| PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| n/a | n/a | 9 | 6 | n/a | n/a | n/a | 7.3 | 25 |
CNRS
| Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co... |
J Med Chem 50: 5790-5806 (2007)
Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50227167
((S)-N-((R)-1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-meth...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCCN2)cc1 |w:37.41| Show InChI InChI=1S/C35H37N7O2/c1-44-26-15-12-23(13-16-26)22-42-33(17-14-24-20-37-29-9-4-2-7-27(24)29)40-41-34(42)32(39-35(43)31-11-6-18-36-31)19-25-21-38-30-10-5-3-8-28(25)30/h2-5,7-10,12-13,15-16,20-21,31-32,36-38H,6,11,14,17-19,22H2,1H3,(H,39,43)/t31?,32-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
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| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-Université Montpellier I
Curated by ChEMBL
| Assay Description
Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cells |
Bioorg Med Chem Lett 18: 164-8 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.113
BindingDB Entry DOI: 10.7270/Q2HM586C |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19310
((2S)-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphe...)Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2)cc1 |r| Show InChI InChI=1S/C33H36N6O2/c1-41-26-16-13-24(14-17-26)22-39-31(18-15-23-8-3-2-4-9-23)37-38-32(39)30(36-33(40)29-12-7-19-34-29)20-25-21-35-28-11-6-5-10-27(25)28/h2-6,8-11,13-14,16-17,21,29-30,34-35H,7,12,15,18-20,22H2,1H3,(H,36,40)/t29-,30+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
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AffyNet
| PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| n/a | n/a | 9.5 | 13 | n/a | n/a | n/a | 7.3 | 25 |
CNRS
| Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co... |
J Med Chem 50: 5790-5806 (2007)
Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM19321
((3S)-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3...)Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCNC2)cc1 |r| Show InChI InChI=1S/C36H39N7O2/c1-45-28-15-12-24(13-16-28)23-43-34(17-14-25-21-38-31-10-4-2-8-29(25)31)41-42-35(43)33(40-36(44)26-7-6-18-37-20-26)19-27-22-39-32-11-5-3-9-30(27)32/h2-5,8-13,15-16,21-22,26,33,37-39H,6-7,14,17-20,23H2,1H3,(H,40,44)/t26-,33+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | 2.5 | n/a | n/a | 7.3 | 25 |
CNRS
| Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co... |
J Med Chem 50: 5790-5806 (2007)
Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4 |
More data for this
Ligand-Target Pair | |
Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634316
(8,14-dioxa-4,10,19,20- | US20230357269, Example 1) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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| PC cid
PC sid
UniChem
| | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634318
(4-fluoro-8,14-dioxa-10,19,20- | US20230357269, Exa...)Show SMILES Fc1cc2COC(=O)NCCCOc3ccc4[nH]nc(-c(c1)c2)c4c3 | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634319
(8,14-dioxa-10,19,20,23- | US20230357269, Example 4) | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634320
(8,14-dioxa-10,19,20- | US20230357269, Example 5) | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634322
(8,14-dioxa-5,10,19,20- | US20230357269, Example 7) | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634323
(4-methoxy-8,14-dioxa-10,19,20- | US20230357269, Ex...)Show SMILES COc1cc2COC(=O)NCCCOc3ccc4[nH]nc(-c(c2)c1)c4c3 | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634324
(4-bromo-8,14-dioxa-10,19,20- | US20230357269, Exam...)Show SMILES Brc1cc2COC(=O)NCCCOc3ccc4[nH]nc(-c(c1)c2)c4c3 | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634325
(5-fluoro-8,14-dioxa-10,19,20- | US20230357269, Exa...) | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634326
(5-methyl-8,14-dioxa-10,19,20- | US20230357269, Exa...) | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634327
(4-(pyrrolidin-1-yl)-8,14-dioxa-10,19,20- | US20230...)Show SMILES O=C1NCCCOc2ccc3[nH]nc(-c4cc(CO1)cc(c4)N1CCCC1)c3c2 | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634328
(4-[4-(propan-2-yl)piperazin-1-yl]-8,14-dioxa- | US...)Show SMILES CC(C)N1CCN(CC1)c1cc2COC(=O)NCCCOc3ccc4[nH]nc(-c(c2)c1)c4c3 | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM50580006
(CHEMBL5090730 | US20230357269, Example 14)Show SMILES O=C1NCCCOc2ccc3[nH]nc(-c4cc(CO1)cc(c4)N1CCC4(COC4)C1)c3c2 | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM50580007
(CHEMBL5072941 | US20230357269, Example 15)Show SMILES O=C1NCCCOc2ccc3[nH]nc(-c4cc(CO1)cc(c4)N1CCN(CC1)C1COC1)c3c2 | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634331
(4-(morpholin-4-yl)-8,14-dioxa-10,19,20- | US202303...)Show SMILES O=C1NCCCOc2ccc3[nH]nc(-c4cc(CO1)cc(c4)N1CCOCC1)c3c2 | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634332
(4-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-8,14- | US2...)Show SMILES C[C@H]1CN(C[C@@H](C)O1)c1cc2COC(=O)NCCCOc3ccc4[nH]nc(-c(c2)c1)c4c3 |r| | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634333
(4-methyl-8,14-dioxa-10,19,20- | US20230357269, Exa...)Show SMILES Cc1cc2COC(=O)NCCCOc3ccc4[nH]nc(-c(c1)c2)c4c3 | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634334
(5-methoxy-8,14-dioxa-10,19,20- | US20230357269, Ex...) | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634335
(4-(4,4-difluoropiperidin-1-yl)-8,14-dioxa- | US202...)Show SMILES FC1(F)CCN(CC1)c1cc2COC(=O)NCCCOc3ccc4[nH]nc(-c(c2)c1)c4c3 | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634336
(4-(3,3-difluoropyrrolidin-1-yl)-8,14-dioxa- | US20...)Show SMILES FC1(F)CCN(C1)c1cc2COC(=O)NCCCOc3ccc4[nH]nc(-c(c2)c1)c4c3 | PDB
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Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM634337
(7-methyl-8,14-dioxa-10,19,20- | US20230357269, Exa...) | PDB
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