Compile Data Set for Download or QSAR

Found 602 hits with Last Name = 'nefzi' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50369460 (CHEMBL1788109) Show SMILES C[C@@H](SC(C)=O)C(=O)N1[C@@H](C[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C17H19NO6S/c1-9(25-10(2)19)15(20)18-13(17(23)24)8-12(16(21)22)14(18)11-6-4-3-5-7-11/h3-7,9,12-14H,8H2,1-2H3,(H,21,22)(H,23,24)/t9-,12+,13+,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	PubMed	0.160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Enzyme inhibitory activity towards Angiotensin I converting enzyme				J Med Chem 42: 3743-78 (1999) BindingDB Entry DOI: 10.7270/Q22Z167W
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50120216 (2-Amino-N-[({[1-benzyl-2-(5-isobutyl-4-oxo-imidazo...) Show SMILES CC(C)C[C@@H]1N(CNC1=O)C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C29H38N6O6/c1-18(2)12-24-28(40)33-17-35(24)29(41)23(14-19-6-4-3-5-7-19)34-26(38)16-31-25(37)15-32-27(39)22(30)13-20-8-10-21(36)11-9-20/h3-11,18,22-24,36H,12-17,30H2,1-2H3,(H,31,37)(H,32,39)(H,33,40)(H,34,38)/t22-,23-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.				Bioorg Med Chem Lett 12: 3175-8 (2002) BindingDB Entry DOI: 10.7270/Q2862FSM
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50094772 (CHEMBL3589796) Show SMILES CC(C)C[C@H]1CN2[C@@H](Cc3ccc(O)cc3)CN3[C@H](CN=C3C=C2N1CCc1ccccc1)C(C)C |r,c:21,24| Show InChI InChI=1S/C25H22N4O3/c1-32-20-10-6-5-9-18(20)24(30)28-23-25(31)29-12-11-16-13-17(26)14-19(22(16)29)21(27-23)15-7-3-2-4-8-15/h2-10,13-14,23H,11-12,26H2,1H3,(H,28,30)/t23-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cortices and cerebella by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001465 ((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.				Bioorg Med Chem Lett 12: 3175-8 (2002) BindingDB Entry DOI: 10.7270/Q2862FSM
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50120219 ((S)-2-{[(S)-2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-...) Show SMILES CNC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C30H42N6O6/c1-19(2)14-25(29(41)32-3)36(4)30(42)24(16-20-8-6-5-7-9-20)35-27(39)18-33-26(38)17-34-28(40)23(31)15-21-10-12-22(37)13-11-21/h5-13,19,23-25,37H,14-18,31H2,1-4H3,(H,32,41)(H,33,38)(H,34,40)(H,35,39)/t23-,24-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.				Bioorg Med Chem Lett 12: 3175-8 (2002) BindingDB Entry DOI: 10.7270/Q2862FSM
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50001465 ((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity of the compound towards Opioid receptor delta 1 was determined using [d-Ser2, Leu5, Thr6] enkephalin (DSLET) as the radioligand.				Bioorg Med Chem Lett 12: 3175-8 (2002) BindingDB Entry DOI: 10.7270/Q2862FSM
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50094772 (CHEMBL3589796) Show SMILES CC(C)C[C@H]1CN2[C@@H](Cc3ccc(O)cc3)CN3[C@H](CN=C3C=C2N1CCc1ccccc1)C(C)C |r,c:21,24| Show InChI InChI=1S/C25H22N4O3/c1-32-20-10-6-5-9-18(20)24(30)28-23-25(31)29-12-11-16-13-17(26)14-19(22(16)29)21(27-23)15-7-3-2-4-8-15/h2-10,13-14,23H,11-12,26H2,1H3,(H,28,30)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50094764 (CHEMBL3589705) Show SMILES CC(C)C[C@H]1CN2[C@@H](Cc3ccc(O)cc3)CN3[C@@H](Cc4ccccc4)CN=C3C=C2N1CCc1ccccc1 |r,c:29,32| Show InChI InChI=1S/C23H19N5O2/c24-17-12-16-8-11-28-20(16)18(13-17)19(14-4-2-1-3-5-14)26-21(23(28)30)27-22(29)15-6-9-25-10-7-15/h1-7,9-10,12-13,21H,8,11,24H2,(H,27,29)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50120217 ((S)-2-{[(S)-2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-...) Show SMILES CC(C)C[C@H](N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O Show InChI InChI=1S/C29H40N6O6/c1-18(2)13-24(27(31)39)35(3)29(41)23(15-19-7-5-4-6-8-19)34-26(38)17-32-25(37)16-33-28(40)22(30)14-20-9-11-21(36)12-10-20/h4-12,18,22-24,36H,13-17,30H2,1-3H3,(H2,31,39)(H,32,37)(H,33,40)(H,34,38)/t22-,23-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.				Bioorg Med Chem Lett 12: 3175-8 (2002) BindingDB Entry DOI: 10.7270/Q2862FSM
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50094774 (CHEMBL3589798) Show SMILES Oc1ccc(C[C@H]2CN3[C@@H](Cc4ccccc4)CN4[C@@H](Cc5ccc(O)cc5)CN=C4C=C3N2CCc2ccccc2)cc1 |r,c:31,34| Show InChI InChI=1S/C28H28N6O4/c1-28(2,3)38-27(37)31-21-15-30-11-9-19(21)25(35)33-24-26(36)34-12-10-17-13-18(29)14-20(23(17)34)22(32-24)16-7-5-4-6-8-16/h4-9,11,13-15,24H,10,12,29H2,1-3H3,(H,31,37)(H,33,35)/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50094763 (CHEMBL3589704) Show SMILES CC(C)C[C@H]1CN2[C@@H](Cc3ccc(O)cc3)CN3[C@@H](Cc4ccccc4)CN=C3C=C2N1 |r,c:29,32| Show InChI InChI=1S/C28H25Cl2N5O2/c29-21-13-18(14-22(30)23(21)31)27(36)33-26-28(37)35-11-8-17-12-19(34-9-4-5-10-34)15-20(25(17)35)24(32-26)16-6-2-1-3-7-16/h1-3,6-7,12-15,26H,4-5,8-11,31H2,(H,33,36)/t26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50101997 (CHEMBL3326769) Show SMILES CC(C)C[C@@H](CN)NC[C@H](Cc1ccccc1)N(C)C[C@@H]1CCCN1C[C@H](Cc1ccc(O)cc1)N(C)C |r| Show InChI InChI=1S/C32H53N5O/c1-25(2)18-28(21-33)34-22-30(19-26-10-7-6-8-11-26)36(5)23-29-12-9-17-37(29)24-31(35(3)4)20-27-13-15-32(38)16-14-27/h6-8,10-11,13-16,25,28-31,34,38H,9,12,17-24,33H2,1-5H3/t28-,29-,30-,31-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Monastir Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation counting analysis				Bioorg Med Chem Lett 24: 4482-5 (2014) Article DOI: 10.1016/j.bmcl.2014.07.090 BindingDB Entry DOI: 10.7270/Q26T0PDD
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50071508 ((2S,3S)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-diox...) Show SMILES CC[C@H](C)[C@@H](C(=O)NCc1ccccc1)n1c(O)c(CCCCN)n(Cc2ccccc2)c1=O Show InChI InChI=1S/C27H36N4O3/c1-3-20(2)24(25(32)29-18-21-12-6-4-7-13-21)31-26(33)23(16-10-11-17-28)30(27(31)34)19-22-14-8-5-9-15-22/h4-9,12-15,20,24,33H,3,10-11,16-19,28H2,1-2H3,(H,29,32)/t20-,24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity for [3H]- pentazocine at sigma opioid receptor				Bioorg Med Chem Lett 8: 2273-8 (1999) BindingDB Entry DOI: 10.7270/Q2PN94T6
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50071501 ((R)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-dioxo-im...) Show SMILES CCC[C@H](C(=O)NCc1ccccc1)n1c(O)c(CCCCN)n(Cc2ccccc2)c1=O Show InChI InChI=1S/C26H34N4O3/c1-2-11-22(24(31)28-18-20-12-5-3-6-13-20)30-25(32)23(16-9-10-17-27)29(26(30)33)19-21-14-7-4-8-15-21/h3-8,12-15,22,32H,2,9-11,16-19,27H2,1H3,(H,28,31)/t22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity for [3H]- pentazocine at sigma opioid receptor				Bioorg Med Chem Lett 8: 2273-8 (1999) BindingDB Entry DOI: 10.7270/Q2PN94T6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50120217 ((S)-2-{[(S)-2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-...) Show SMILES CC(C)C[C@H](N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O Show InChI InChI=1S/C29H40N6O6/c1-18(2)13-24(27(31)39)35(3)29(41)23(15-19-7-5-4-6-8-19)34-26(38)17-32-25(37)16-33-28(40)22(30)14-20-9-11-21(36)12-10-20/h4-12,18,22-24,36H,13-17,30H2,1-3H3,(H2,31,39)(H,32,37)(H,33,40)(H,34,38)/t22-,23-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity of the compound towards Opioid receptor delta 1 was determined using [d-Ser2, Leu5, Thr6] enkephalin (DSLET) as the radioligand.				Bioorg Med Chem Lett 12: 3175-8 (2002) BindingDB Entry DOI: 10.7270/Q2862FSM
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50094773 (CHEMBL3589797) Show SMILES Oc1ccc(C[C@H]2CN3[C@@H](Cc4ccccc4)CN4[C@@H](Cc5ccc(O)cc5)CN=C4C=C3N2)cc1 |r,c:31,34| Show InChI InChI=1S/C24H20N4O3/c1-31-18-13-17-9-12-28-21(17)19(14-18)20(15-5-3-2-4-6-15)26-22(24(28)30)27-23(29)16-7-10-25-11-8-16/h2-8,10-11,13-14,22H,9,12H2,1H3,(H,27,29)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50071501 ((R)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-dioxo-im...) Show SMILES CCC[C@H](C(=O)NCc1ccccc1)n1c(O)c(CCCCN)n(Cc2ccccc2)c1=O Show InChI InChI=1S/C26H34N4O3/c1-2-11-22(24(31)28-18-20-12-5-3-6-13-20)30-25(32)23(16-9-10-17-27)29(26(30)33)19-21-14-7-4-8-15-21/h3-8,12-15,22,32H,2,9-11,16-19,27H2,1H3,(H,28,31)/t22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity for [3H]- pentazocine at sigma opioid receptor				Bioorg Med Chem Lett 8: 2273-8 (1999) BindingDB Entry DOI: 10.7270/Q2PN94T6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50120220 (2-[1-{3-[2-amino-3-(4-hydroxyphenyl)-(2S)-propanoy...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CN1CN(CC1=O)C(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O Show InChI InChI=1S/C29H38N6O6/c1-18(2)12-23(27(31)39)33-28(40)24(14-19-6-4-3-5-7-19)32-25(37)15-34-17-35(16-26(34)38)29(41)22(30)13-20-8-10-21(36)11-9-20/h3-11,18,22-24,36H,12-17,30H2,1-2H3,(H2,31,39)(H,32,37)(H,33,40)/t22-,23-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.				Bioorg Med Chem Lett 12: 3175-8 (2002) BindingDB Entry DOI: 10.7270/Q2862FSM
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50120213 ((S)-2-[(S)-2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-p...) Show SMILES CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C29H40N6O6/c1-18(2)13-23(28(40)31-3)35-29(41)24(15-19-7-5-4-6-8-19)34-26(38)17-32-25(37)16-33-27(39)22(30)14-20-9-11-21(36)12-10-20/h4-12,18,22-24,36H,13-17,30H2,1-3H3,(H,31,40)(H,32,37)(H,33,39)(H,34,38)(H,35,41)/t22-,23-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity of the compound towards Opioid receptor delta 1 was determined using [d-Ser2, Leu5, Thr6] enkephalin (DSLET) as the radioligand.				Bioorg Med Chem Lett 12: 3175-8 (2002) BindingDB Entry DOI: 10.7270/Q2862FSM
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50120216 (2-Amino-N-[({[1-benzyl-2-(5-isobutyl-4-oxo-imidazo...) Show SMILES CC(C)C[C@@H]1N(CNC1=O)C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C29H38N6O6/c1-18(2)12-24-28(40)33-17-35(24)29(41)23(14-19-6-4-3-5-7-19)34-26(38)16-31-25(37)15-32-27(39)22(30)13-20-8-10-21(36)11-9-20/h3-11,18,22-24,36H,12-17,30H2,1-2H3,(H,31,37)(H,32,39)(H,33,40)(H,34,38)/t22-,23-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity of the compound towards Opioid receptor delta 1 was determined using [d-Ser2, Leu5, Thr6] enkephalin (DSLET) as the radioligand.				Bioorg Med Chem Lett 12: 3175-8 (2002) BindingDB Entry DOI: 10.7270/Q2862FSM
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50071506 ((2R,3R)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-diox...) Show SMILES CC[C@@H](C)[C@H](C(=O)NCc1ccccc1)n1c(O)c(CCCCN)n(Cc2ccccc2)c1=O Show InChI InChI=1S/C27H36N4O3/c1-3-20(2)24(25(32)29-18-21-12-6-4-7-13-21)31-26(33)23(16-10-11-17-28)30(27(31)34)19-22-14-8-5-9-15-22/h4-9,12-15,20,24,33H,3,10-11,16-19,28H2,1-2H3,(H,29,32)/t20-,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity for [3H]- pentazocine at sigma opioid receptor				Bioorg Med Chem Lett 8: 2273-8 (1999) BindingDB Entry DOI: 10.7270/Q2PN94T6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50120218 ((1S,3S)-2-[2-(3-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)N1CN(CC1=O)C(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O Show InChI InChI=1S/C29H38N6O6/c1-18(2)12-23(27(31)39)33-29(41)24(14-19-6-4-3-5-7-19)35-17-34(16-26(35)38)25(37)15-32-28(40)22(30)13-20-8-10-21(36)11-9-20/h3-11,18,22-24,36H,12-17,30H2,1-2H3,(H2,31,39)(H,32,40)(H,33,41)/t22-,23-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity of the compound towards Opioid receptor delta 1 was determined using [d-Ser2, Leu5, Thr6] enkephalin (DSLET) as the radioligand.				Bioorg Med Chem Lett 12: 3175-8 (2002) BindingDB Entry DOI: 10.7270/Q2862FSM
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50120213 ((S)-2-[(S)-2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-p...) Show SMILES CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C29H40N6O6/c1-18(2)13-23(28(40)31-3)35-29(41)24(15-19-7-5-4-6-8-19)34-26(38)17-32-25(37)16-33-27(39)22(30)14-20-9-11-21(36)12-10-20/h4-12,18,22-24,36H,13-17,30H2,1-3H3,(H,31,40)(H,32,37)(H,33,39)(H,34,38)(H,35,41)/t22-,23-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.				Bioorg Med Chem Lett 12: 3175-8 (2002) BindingDB Entry DOI: 10.7270/Q2862FSM
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50094766 (CHEMBL3589707) Show SMILES Oc1ccc(C[C@H]2CN3[C@@H](Cc4ccc(O)cc4)CN4[C@@H](Cc5ccccc5)CN=C4C=C3N2CCc2ccccc2)cc1 |r,c:31,34| Show InChI InChI=1S/C23H16Cl2N4O2/c24-16-11-26-12-17(25)18(16)22(30)28-21-23(31)29-10-9-14-7-4-8-15(20(14)29)19(27-21)13-5-2-1-3-6-13/h1-8,11-12,21H,9-10H2,(H,28,30)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	188	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50071504 ((R)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-dioxo-im...) Show SMILES NCCCCc1c(O)n([C@H](CC2CCCCC2)C(N)=O)c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C23H34N4O3/c24-14-8-7-13-19-22(29)27(20(21(25)28)15-17-9-3-1-4-10-17)23(30)26(19)16-18-11-5-2-6-12-18/h2,5-6,11-12,17,20,29H,1,3-4,7-10,13-16,24H2,(H2,25,28)/t20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	189	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity for [3H]- pentazocine at sigma opioid receptor				Bioorg Med Chem Lett 8: 2273-8 (1999) BindingDB Entry DOI: 10.7270/Q2PN94T6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50120219 ((S)-2-{[(S)-2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-...) Show SMILES CNC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C30H42N6O6/c1-19(2)14-25(29(41)32-3)36(4)30(42)24(16-20-8-6-5-7-9-20)35-27(39)18-33-26(38)17-34-28(40)23(31)15-21-10-12-22(37)13-11-21/h5-13,19,23-25,37H,14-18,31H2,1-4H3,(H,32,41)(H,33,38)(H,34,40)(H,35,39)/t23-,24-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	209	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity of the compound towards Opioid receptor delta 1 was determined using [d-Ser2, Leu5, Thr6] enkephalin (DSLET) as the radioligand.				Bioorg Med Chem Lett 12: 3175-8 (2002) BindingDB Entry DOI: 10.7270/Q2862FSM
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50094771 (CHEMBL3589795) Show SMILES CC(C)C[C@H]1CN2[C@@H](Cc3ccc(O)cc3)CN3[C@H](CN=C3C=C2N1)C(C)C |r,c:21,24| Show InChI InChI=1S/C27H21N5O2/c28-20-12-18-10-11-32-24(18)21(14-20)23(16-6-2-1-3-7-16)30-25(27(32)34)31-26(33)22-13-17-8-4-5-9-19(17)15-29-22/h1-9,12-15,25H,10-11,28H2,(H,31,33)/t25-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	209	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cortices and cerebella by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50094771 (CHEMBL3589795) Show SMILES CC(C)C[C@H]1CN2[C@@H](Cc3ccc(O)cc3)CN3[C@H](CN=C3C=C2N1)C(C)C |r,c:21,24| Show InChI InChI=1S/C27H21N5O2/c28-20-12-18-10-11-32-24(18)21(14-20)23(16-6-2-1-3-7-16)30-25(27(32)34)31-26(33)22-13-17-8-4-5-9-19(17)15-29-22/h1-9,12-15,25H,10-11,28H2,(H,31,33)/t25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	215	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50120220 (2-[1-{3-[2-amino-3-(4-hydroxyphenyl)-(2S)-propanoy...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CN1CN(CC1=O)C(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O Show InChI InChI=1S/C29H38N6O6/c1-18(2)12-23(27(31)39)33-28(40)24(14-19-6-4-3-5-7-19)32-25(37)15-34-17-35(16-26(34)38)29(41)22(30)13-20-8-10-21(36)11-9-20/h3-11,18,22-24,36H,12-17,30H2,1-2H3,(H2,31,39)(H,32,37)(H,33,40)/t22-,23-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	229	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity of the compound towards Opioid receptor delta 1 was determined using [d-Ser2, Leu5, Thr6] enkephalin (DSLET) as the radioligand.				Bioorg Med Chem Lett 12: 3175-8 (2002) BindingDB Entry DOI: 10.7270/Q2862FSM
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50120218 ((1S,3S)-2-[2-(3-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)N1CN(CC1=O)C(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O Show InChI InChI=1S/C29H38N6O6/c1-18(2)12-23(27(31)39)33-29(41)24(14-19-6-4-3-5-7-19)35-17-34(16-26(35)38)25(37)15-32-28(40)22(30)13-20-8-10-21(36)11-9-20/h3-11,18,22-24,36H,12-17,30H2,1-2H3,(H2,31,39)(H,32,40)(H,33,41)/t22-,23-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	236	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.				Bioorg Med Chem Lett 12: 3175-8 (2002) BindingDB Entry DOI: 10.7270/Q2862FSM
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50094776 (CHEMBL3589800) Show SMILES Oc1ccc(C[C@H]2CN3[C@@H](Cc4ccc(O)cc4)CN4[C@@H](Cc5ccc(O)cc5)CN=C4C=C3N2CCc2ccccc2)cc1 |r,c:32,35| Show InChI InChI=1S/C23H18N4O2/c28-22(17-9-12-24-13-10-17)26-21-23(29)27-14-11-16-7-4-8-18(20(16)27)19(25-21)15-5-2-1-3-6-15/h1-10,12-13,21H,11,14H2,(H,26,28)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	246	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50101998 (CHEMBL3326768) Show SMILES CC(C)C[C@H]1CNC(=O)C(=O)N1C[C@H](Cc1ccccc1)N(C)C[C@@H]1CCCN1C[C@H](Cc1ccc(O)cc1)N(C)C |r| Show InChI InChI=1S/C34H51N5O3/c1-25(2)18-29-21-35-33(41)34(42)39(29)24-31(20-26-10-7-6-8-11-26)37(5)22-28-12-9-17-38(28)23-30(36(3)4)19-27-13-15-32(40)16-14-27/h6-8,10-11,13-16,25,28-31,40H,9,12,17-24H2,1-5H3,(H,35,41)/t28-,29-,30-,31-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Monastir Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation counting analysis				Bioorg Med Chem Lett 24: 4482-5 (2014) Article DOI: 10.1016/j.bmcl.2014.07.090 BindingDB Entry DOI: 10.7270/Q26T0PDD
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50071510 ((S)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-dioxo-im...) Show SMILES NCCCCc1c(O)n([C@@H](CC2CCCCC2)C(N)=O)c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C23H34N4O3/c24-14-8-7-13-19-22(29)27(20(21(25)28)15-17-9-3-1-4-10-17)23(30)26(19)16-18-11-5-2-6-12-18/h2,5-6,11-12,17,20,29H,1,3-4,7-10,13-16,24H2,(H2,25,28)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	254	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity for [3H]- pentazocine at sigma opioid receptor				Bioorg Med Chem Lett 8: 2273-8 (1999) BindingDB Entry DOI: 10.7270/Q2PN94T6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50094775 (CHEMBL3589799) Show SMILES Oc1ccc(C[C@H]2CN3[C@@H](Cc4ccc(O)cc4)CN4[C@@H](Cc5ccc(O)cc5)CN=C4C=C3N2)cc1 |r,c:32,35| Show InChI InChI=1S/C24H18Cl2N4O2/c1-13-9-15-7-8-30-21(15)16(10-13)20(14-5-3-2-4-6-14)28-22(24(30)32)29-23(31)19-17(25)11-27-12-18(19)26/h2-6,9-12,22H,7-8H2,1H3,(H,29,31)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50071502 ((2R,3S)-2-[(R)-4-(3-Amino-propyl)-3-benzyl-2,5-dio...) Show SMILES CC[C@H](C)[C@H](C(=O)NCc1ccccc1)n1c(O)c(CCCN)n(Cc2ccccc2)c1=O Show InChI InChI=1S/C26H34N4O3/c1-3-19(2)23(24(31)28-17-20-11-6-4-7-12-20)30-25(32)22(15-10-16-27)29(26(30)33)18-21-13-8-5-9-14-21/h4-9,11-14,19,23,32H,3,10,15-18,27H2,1-2H3,(H,28,31)/t19-,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	333	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity for [3H]- pentazocine at sigma opioid receptor				Bioorg Med Chem Lett 8: 2273-8 (1999) BindingDB Entry DOI: 10.7270/Q2PN94T6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50094765 (CHEMBL3589706) Show SMILES Oc1ccc(C[C@H]2CN3[C@@H](Cc4ccc(O)cc4)CN4[C@@H](Cc5ccccc5)CN=C4C=C3N2)cc1 |r,c:31,34| Show InChI InChI=1S/C23H19N5O2/c24-18-13-25-11-9-16(18)22(29)27-21-23(30)28-12-10-15-7-4-8-17(20(15)28)19(26-21)14-5-2-1-3-6-14/h1-9,11,13,21H,10,12,24H2,(H,27,29)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	338	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50094776 (CHEMBL3589800) Show SMILES Oc1ccc(C[C@H]2CN3[C@@H](Cc4ccc(O)cc4)CN4[C@@H](Cc5ccc(O)cc5)CN=C4C=C3N2CCc2ccccc2)cc1 |r,c:32,35| Show InChI InChI=1S/C23H18N4O2/c28-22(17-9-12-24-13-10-17)26-21-23(29)27-14-11-16-7-4-8-18(20(16)27)19(25-21)15-5-2-1-3-6-15/h1-10,12-13,21H,11,14H2,(H,26,28)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	392	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50094774 (CHEMBL3589798) Show SMILES Oc1ccc(C[C@H]2CN3[C@@H](Cc4ccccc4)CN4[C@@H](Cc5ccc(O)cc5)CN=C4C=C3N2CCc2ccccc2)cc1 |r,c:31,34| Show InChI InChI=1S/C28H28N6O4/c1-28(2,3)38-27(37)31-21-15-30-11-9-19(21)25(35)33-24-26(36)34-12-10-17-13-18(29)14-20(23(17)34)22(32-24)16-7-5-4-6-8-16/h4-9,11,13-15,24H,10,12,29H2,1-3H3,(H,31,37)(H,33,35)/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	393	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50071511 ((R)-2-[(S)-4-(3-Amino-propyl)-3-benzyl-2,5-dioxo-i...) Show SMILES NCCCc1c(O)n([C@H](CC2CCCCC2)C(N)=O)c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C22H32N4O3/c23-13-7-12-18-21(28)26(19(20(24)27)14-16-8-3-1-4-9-16)22(29)25(18)15-17-10-5-2-6-11-17/h2,5-6,10-11,16,19,28H,1,3-4,7-9,12-15,23H2,(H2,24,27)/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	406	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity for [3H]- pentazocine at sigma opioid receptor				Bioorg Med Chem Lett 8: 2273-8 (1999) BindingDB Entry DOI: 10.7270/Q2PN94T6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50102027 (CHEMBL3326767) Show SMILES CC(C)C[C@H]1CNC(=S)N1C[C@H](Cc1ccccc1)N(C)C[C@@H]1CCCN1C[C@H](Cc1ccc(O)cc1)N(C)C |r| Show InChI InChI=1S/C33H51N5OS/c1-25(2)18-29-21-34-33(40)38(29)24-31(20-26-10-7-6-8-11-26)36(5)22-28-12-9-17-37(28)23-30(35(3)4)19-27-13-15-32(39)16-14-27/h6-8,10-11,13-16,25,28-31,39H,9,12,17-24H2,1-5H3,(H,34,40)/t28-,29-,30-,31-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Monastir Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation counting analysis				Bioorg Med Chem Lett 24: 4482-5 (2014) Article DOI: 10.1016/j.bmcl.2014.07.090 BindingDB Entry DOI: 10.7270/Q26T0PDD
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50071509 ((R)-2-[(R)-4-(3-Amino-propyl)-3-benzyl-2,5-dioxo-i...) Show SMILES CCC[C@H](C(=O)NCc1ccccc1)n1c(O)c(CCCN)n(Cc2ccccc2)c1=O Show InChI InChI=1S/C25H32N4O3/c1-2-10-21(23(30)27-17-19-11-5-3-6-12-19)29-24(31)22(15-9-16-26)28(25(29)32)18-20-13-7-4-8-14-20/h3-8,11-14,21,31H,2,9-10,15-18,26H2,1H3,(H,27,30)/t21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	435	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity for [3H]- pentazocine at sigma opioid receptor				Bioorg Med Chem Lett 8: 2273-8 (1999) BindingDB Entry DOI: 10.7270/Q2PN94T6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50120215 ((S)-2-[(S)-2-(2-{2-[4-((S)-4-Hydroxy-benzyl)-5-oxo...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN1CN[C@@H](Cc2ccc(O)cc2)C1=O)C(N)=O Show InChI InChI=1S/C29H38N6O6/c1-18(2)12-22(27(30)39)34-28(40)23(13-19-6-4-3-5-7-19)33-25(37)15-31-26(38)16-35-17-32-24(29(35)41)14-20-8-10-21(36)11-9-20/h3-11,18,22-24,32,36H,12-17H2,1-2H3,(H2,30,39)(H,31,38)(H,33,37)(H,34,40)/t22-,23-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	547	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Molecular Studies Curated by ChEMBL					Assay Description Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.				Bioorg Med Chem Lett 12: 3175-8 (2002) BindingDB Entry DOI: 10.7270/Q2862FSM
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50094775 (CHEMBL3589799) Show SMILES Oc1ccc(C[C@H]2CN3[C@@H](Cc4ccc(O)cc4)CN4[C@@H](Cc5ccc(O)cc5)CN=C4C=C3N2)cc1 |r,c:32,35| Show InChI InChI=1S/C24H18Cl2N4O2/c1-13-9-15-7-8-30-21(15)16(10-13)20(14-5-3-2-4-6-14)28-22(24(30)32)29-23(31)19-17(25)11-27-12-18(19)26/h2-6,9-12,22H,7-8H2,1H3,(H,29,31)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	552	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50094761 (CHEMBL3589702) Show SMILES Oc1ccc(C[C@H]2CN3[C@@H](Cc4ccccc4)CN4[C@@H](Cc5ccccc5)CN=C4C=C3N2)cc1 |r,c:30,33| Show InChI InChI=1S/C30H32N4O/c35-28-13-11-24(12-14-28)15-25-20-33-27(17-23-9-5-2-6-10-23)21-34-26(16-22-7-3-1-4-8-22)19-31-29(34)18-30(33)32-25/h1-14,18,25-27,32,35H,15-17,19-21H2/t25-,26-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	566	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50094773 (CHEMBL3589797) Show SMILES Oc1ccc(C[C@H]2CN3[C@@H](Cc4ccccc4)CN4[C@@H](Cc5ccc(O)cc5)CN=C4C=C3N2)cc1 |r,c:31,34| Show InChI InChI=1S/C24H20N4O3/c1-31-18-13-17-9-12-28-21(17)19(14-18)20(15-5-3-2-4-6-15)26-22(24(28)30)27-23(29)16-7-10-25-11-8-16/h2-8,10-11,13-14,22H,9,12H2,1H3,(H,27,29)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	605	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50094764 (CHEMBL3589705) Show SMILES CC(C)C[C@H]1CN2[C@@H](Cc3ccc(O)cc3)CN3[C@@H](Cc4ccccc4)CN=C3C=C2N1CCc1ccccc1 |r,c:29,32| Show InChI InChI=1S/C23H19N5O2/c24-17-12-16-8-11-28-20(16)18(13-17)19(14-4-2-1-3-5-14)26-21(23(28)30)27-22(29)15-6-9-25-10-7-15/h1-7,9-10,12-13,21H,8,11,24H2,(H,27,29)/t21-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	642	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cortices and cerebella by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50094772 (CHEMBL3589796) Show SMILES CC(C)C[C@H]1CN2[C@@H](Cc3ccc(O)cc3)CN3[C@H](CN=C3C=C2N1CCc1ccccc1)C(C)C |r,c:21,24| Show InChI InChI=1S/C25H22N4O3/c1-32-20-10-6-5-9-18(20)24(30)28-23-25(31)29-12-11-16-13-17(26)14-19(22(16)29)21(27-23)15-7-3-2-4-8-15/h2-10,13-14,23H,11-12,26H2,1H3,(H,28,30)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	721	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50102073 (CHEMBL3326662) Show SMILES CC(C)C[C@H]1CNC(=S)N1C[C@H](Cc1ccccc1)N(C)CCN1CCN(C[C@H](Cc2ccc(O)cc2)N(C)C)C1=S |r| Show InChI InChI=1S/C33H50N6OS2/c1-25(2)19-28-22-34-32(41)39(28)24-30(21-26-9-7-6-8-10-26)36(5)15-16-37-17-18-38(33(37)42)23-29(35(3)4)20-27-11-13-31(40)14-12-27/h6-14,25,28-30,40H,15-24H2,1-5H3,(H,34,41)/t28-,29-,30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Monastir Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation counting analysis				Bioorg Med Chem Lett 24: 4482-5 (2014) Article DOI: 10.1016/j.bmcl.2014.07.090 BindingDB Entry DOI: 10.7270/Q26T0PDD
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50094774 (CHEMBL3589798) Show SMILES Oc1ccc(C[C@H]2CN3[C@@H](Cc4ccccc4)CN4[C@@H](Cc5ccc(O)cc5)CN=C4C=C3N2CCc2ccccc2)cc1 |r,c:31,34| Show InChI InChI=1S/C28H28N6O4/c1-28(2,3)38-27(37)31-21-15-30-11-9-19(21)25(35)33-24-26(36)34-12-10-17-13-18(29)14-20(23(17)34)22(32-24)16-7-5-4-6-8-16/h4-9,11,13-15,24H,10,12,29H2,1-3H3,(H,31,37)(H,33,35)/t24-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	767	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cortices and cerebella by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50094766 (CHEMBL3589707) Show SMILES Oc1ccc(C[C@H]2CN3[C@@H](Cc4ccc(O)cc4)CN4[C@@H](Cc5ccccc5)CN=C4C=C3N2CCc2ccccc2)cc1 |r,c:31,34| Show InChI InChI=1S/C23H16Cl2N4O2/c24-16-11-26-12-17(25)18(16)22(30)28-21-23(31)29-10-9-14-7-4-8-15(20(14)29)19(27-21)13-5-2-1-3-6-13/h1-8,11-12,21H,9-10H2,(H,28,30)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	878	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Torrey Pines Institute for Molecular Studies Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat cortices by competition binding assay				J Med Chem 58: 4905-17 (2015) Article DOI: 10.1021/jm501637c BindingDB Entry DOI: 10.7270/Q2TB18NQ
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 602 total )  |  Next  |  Last  >>

Jump to: