Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM50066275 (CHEMBL3401548) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Technology Sydney Curated by ChEMBL | Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity at 5 uM active compound by Lineweaver-Burk plot analy... | Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM50066274 (CHEMBL3401549) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Technology Sydney Curated by ChEMBL | Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity at 5 uM active compound by Lineweaver-Burk plot analy... | Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 8.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Technology Sydney Curated by ChEMBL | Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity at 5 uM active compound by Lineweaver-Burk plot analy... | Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM50066275 (CHEMBL3401548) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Technology Sydney Curated by ChEMBL | Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity | Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM50066274 (CHEMBL3401549) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Technology Sydney Curated by ChEMBL | Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity | Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.73E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Technology Sydney Curated by ChEMBL | Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity | Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Butyrophilin subfamily 3 member A1 (Homo sapiens (Human)) | BDBM50271369 (CHEMBL4127400) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description Binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cells by upregulation of CD69 and C... | J Med Chem 61: 2111-2117 (2018) Article DOI: 10.1021/acs.jmedchem.7b01824 BindingDB Entry DOI: 10.7270/Q2JD509N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Butyrophilin subfamily 3 member A1 (Homo sapiens (Human)) | BDBM50271365 (CHEMBL4127261) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 8.90 | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description Binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cells by upregulation of CD69 and C... | J Med Chem 61: 2111-2117 (2018) Article DOI: 10.1021/acs.jmedchem.7b01824 BindingDB Entry DOI: 10.7270/Q2JD509N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Butyrophilin subfamily 3 member A1 (Homo sapiens (Human)) | BDBM50236893 (CHEBI:15664 | CHEMBL145233) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 0.0600 | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description Binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cells by upregulation of CD69 and C... | J Med Chem 61: 2111-2117 (2018) Article DOI: 10.1021/acs.jmedchem.7b01824 BindingDB Entry DOI: 10.7270/Q2JD509N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Butyrophilin subfamily 3 member A1 (Homo sapiens (Human)) | BDBM12578 (2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 487 | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description Binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cells by upregulation of CD69 and C... | J Med Chem 61: 2111-2117 (2018) Article DOI: 10.1021/acs.jmedchem.7b01824 BindingDB Entry DOI: 10.7270/Q2JD509N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Butyrophilin subfamily 3 member A1 (Homo sapiens (Human)) | BDBM50271366 (CHEMBL4126163) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description Binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cells by upregulation of CD69 and C... | J Med Chem 61: 2111-2117 (2018) Article DOI: 10.1021/acs.jmedchem.7b01824 BindingDB Entry DOI: 10.7270/Q2JD509N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Butyrophilin subfamily 3 member A1 (Homo sapiens (Human)) | BDBM50271368 (CHEMBL4126016) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.450 | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description Binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cells by upregulation of CD69 and C... | J Med Chem 61: 2111-2117 (2018) Article DOI: 10.1021/acs.jmedchem.7b01824 BindingDB Entry DOI: 10.7270/Q2JD509N | |||||||||||
More data for this Ligand-Target Pair |