Found 38 hits with Last Name = 'jacobsen' and Initial = 'b' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206118
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(N[C@H](CO)Cc2ccccc2Br)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C25H23BrN6O2/c1-15-10-18(32-9-8-27-14-32)12-21-23(15)31-24(30-21)22-20(6-7-28-25(22)34)29-17(13-33)11-16-4-2-3-5-19(16)26/h2-10,12,14,17,33H,11,13H2,1H3,(H,30,31)(H2,28,29,34)/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206120
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(NCc2ccccn2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C22H19N7O/c1-14-10-16(29-9-8-23-13-29)11-18-20(14)28-21(27-18)19-17(5-7-25-22(19)30)26-12-15-4-2-3-6-24-15/h2-11,13H,12H2,1H3,(H,27,28)(H2,25,26,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206141
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(NCCc2ccccn2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C23H21N7O/c1-15-12-17(30-11-10-24-14-30)13-19-21(15)29-22(28-19)20-18(6-9-27-23(20)31)26-8-5-16-4-2-3-7-25-16/h2-4,6-7,9-14H,5,8H2,1H3,(H,28,29)(H2,26,27,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206150
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1ccccc1C[C@@H](CO)Nc1cc[nH]c(=O)c1-c1nc2cc(cc(C)c2[nH]1)-n1ccnc1 Show InChI InChI=1S/C26H26N6O2/c1-16-5-3-4-6-18(16)12-19(14-33)29-21-7-8-28-26(34)23(21)25-30-22-13-20(32-10-9-27-15-32)11-17(2)24(22)31-25/h3-11,13,15,19,33H,12,14H2,1-2H3,(H,30,31)(H2,28,29,34)/t19-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206136
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(N[C@H](CO)Cc2ccccc2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C25H24N6O2/c1-16-11-19(31-10-9-26-15-31)13-21-23(16)30-24(29-21)22-20(7-8-27-25(22)33)28-18(14-32)12-17-5-3-2-4-6-17/h2-11,13,15,18,32H,12,14H2,1H3,(H,29,30)(H2,27,28,33)/t18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206130
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES COc1ccccc1C[C@@H](CO)Nc1cc[nH]c(=O)c1-c1nc2cc(cc(C)c2[nH]1)-n1ccnc1 Show InChI InChI=1S/C26H26N6O3/c1-16-11-19(32-10-9-27-15-32)13-21-24(16)31-25(30-21)23-20(7-8-28-26(23)34)29-18(14-33)12-17-5-3-4-6-22(17)35-2/h3-11,13,15,18,33H,12,14H2,1-2H3,(H,30,31)(H2,28,29,34)/t18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206151
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(N[C@H](CO)Cc2cccc(F)c2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C25H23FN6O2/c1-15-9-19(32-8-7-27-14-32)12-21-23(15)31-24(30-21)22-20(5-6-28-25(22)34)29-18(13-33)11-16-3-2-4-17(26)10-16/h2-10,12,14,18,33H,11,13H2,1H3,(H,30,31)(H2,28,29,34)/t18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206143
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(N[C@H](CO)Cc2cccc(Br)c2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C25H23BrN6O2/c1-15-9-19(32-8-7-27-14-32)12-21-23(15)31-24(30-21)22-20(5-6-28-25(22)34)29-18(13-33)11-16-3-2-4-17(26)10-16/h2-10,12,14,18,33H,11,13H2,1H3,(H,30,31)(H2,28,29,34)/t18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206125
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES COc1cccc(C[C@@H](CO)Nc2cc[nH]c(=O)c2-c2nc3cc(cc(C)c3[nH]2)-n2ccnc2)c1 Show InChI InChI=1S/C26H26N6O3/c1-16-10-19(32-9-8-27-15-32)13-22-24(16)31-25(30-22)23-21(6-7-28-26(23)34)29-18(14-33)11-17-4-3-5-20(12-17)35-2/h3-10,12-13,15,18,33H,11,14H2,1-2H3,(H,30,31)(H2,28,29,34)/t18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206126
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(N[C@H](CO)Cc2cccc(Cl)c2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C25H23ClN6O2/c1-15-9-19(32-8-7-27-14-32)12-21-23(15)31-24(30-21)22-20(5-6-28-25(22)34)29-18(13-33)11-16-3-2-4-17(26)10-16/h2-10,12,14,18,33H,11,13H2,1H3,(H,30,31)(H2,28,29,34)/t18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 730 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206124
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(N[C@H](CO)Cc2ccccc2Cl)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C25H23ClN6O2/c1-15-10-18(32-9-8-27-14-32)12-21-23(15)31-24(30-21)22-20(6-7-28-25(22)34)29-17(13-33)11-16-4-2-3-5-19(16)26/h2-10,12,14,17,33H,11,13H2,1H3,(H,30,31)(H2,28,29,34)/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206147
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(N[C@H](CO)Cc2ccccc2OC(F)(F)F)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C26H23F3N6O3/c1-15-10-18(35-9-8-30-14-35)12-20-23(15)34-24(33-20)22-19(6-7-31-25(22)37)32-17(13-36)11-16-4-2-3-5-21(16)38-26(27,28)29/h2-10,12,14,17,36H,11,13H2,1H3,(H,33,34)(H2,31,32,37)/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206139
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(N[C@H](CO)Cc2ccc(F)cc2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C25H23FN6O2/c1-15-10-19(32-9-8-27-14-32)12-21-23(15)31-24(30-21)22-20(6-7-28-25(22)34)29-18(13-33)11-16-2-4-17(26)5-3-16/h2-10,12,14,18,33H,11,13H2,1H3,(H,30,31)(H2,28,29,34)/t18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206122
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(N[C@H](CO)Cc2ccc(OC(C)(C)C)cc2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C29H32N6O3/c1-18-13-21(35-12-11-30-17-35)15-24-26(18)34-27(33-24)25-23(9-10-31-28(25)37)32-20(16-36)14-19-5-7-22(8-6-19)38-29(2,3)4/h5-13,15,17,20,36H,14,16H2,1-4H3,(H,33,34)(H2,31,32,37)/t20-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50520671
(CHEMBL4459971)Show SMILES CCc1nc(C)cn2nc(cc12)-c1cc(=O)n2cc(cc(C)c2n1)C1CCN(C)CC1 Show InChI InChI=1S/C24H28N6O/c1-5-19-22-11-21(27-30(22)13-16(3)25-19)20-12-23(31)29-14-18(10-15(2)24(29)26-20)17-6-8-28(4)9-7-17/h10-14,17H,5-9H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human ERG at 37 degC |
J Med Chem 61: 6501-6517 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00741
BindingDB Entry DOI: 10.7270/Q24171F3 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206134
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(NCCc2cccs2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C22H20N6OS/c1-14-11-15(28-9-8-23-13-28)12-18-20(14)27-21(26-18)19-17(5-7-25-22(19)29)24-6-4-16-3-2-10-30-16/h2-3,5,7-13H,4,6H2,1H3,(H,26,27)(H2,24,25,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206148
(2-((S)-2-(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(N[C@H](CO)Cc2ccccc2C#N)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C26H23N7O2/c1-16-10-20(33-9-8-28-15-33)12-22-24(16)32-25(31-22)23-21(6-7-29-26(23)35)30-19(14-34)11-17-4-2-3-5-18(17)13-27/h2-10,12,15,19,34H,11,14H2,1H3,(H,31,32)(H2,29,30,35)/t19-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206132
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(NCCn2nccn2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C20H19N9O/c1-13-10-14(28-8-6-21-12-28)11-16-18(13)27-19(26-16)17-15(2-3-23-20(17)30)22-7-9-29-24-4-5-25-29/h2-6,8,10-12H,7,9H2,1H3,(H,26,27)(H2,22,23,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206128
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(NCc2ccco2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C21H18N6O2/c1-13-9-14(27-7-6-22-12-27)10-17-19(13)26-20(25-17)18-16(4-5-23-21(18)28)24-11-15-3-2-8-29-15/h2-10,12H,11H2,1H3,(H,25,26)(H2,23,24,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50201140
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(NCCc2ccccc2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C24H22N6O/c1-16-13-18(30-12-11-25-15-30)14-20-22(16)29-23(28-20)21-19(8-10-27-24(21)31)26-9-7-17-5-3-2-4-6-17/h2-6,8,10-15H,7,9H2,1H3,(H,28,29)(H2,26,27,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206135
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES COc1ccc(C[C@@H](CO)Nc2cc[nH]c(=O)c2-c2nc3cc(cc(C)c3[nH]2)-n2ccnc2)cc1 Show InChI InChI=1S/C26H26N6O3/c1-16-11-19(32-10-9-27-15-32)13-22-24(16)31-25(30-22)23-21(7-8-28-26(23)34)29-18(14-33)12-17-3-5-20(35-2)6-4-17/h3-11,13,15,18,33H,12,14H2,1-2H3,(H,30,31)(H2,28,29,34)/t18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206127
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(N[C@H](CO)Cc2cccc(c2)[N+]([O-])=O)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C25H23N7O4/c1-15-9-19(31-8-7-26-14-31)12-21-23(15)30-24(29-21)22-20(5-6-27-25(22)34)28-17(13-33)10-16-3-2-4-18(11-16)32(35)36/h2-9,11-12,14,17,33H,10,13H2,1H3,(H,29,30)(H2,27,28,34)/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206152
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(N[C@H](CO)Cc2cccc(c2)C(F)(F)F)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C26H23F3N6O2/c1-15-9-19(35-8-7-30-14-35)12-21-23(15)34-24(33-21)22-20(5-6-31-25(22)37)32-18(13-36)11-16-3-2-4-17(10-16)26(27,28)29/h2-10,12,14,18,36H,11,13H2,1H3,(H,33,34)(H2,31,32,37)/t18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50201127
(3-(5-(1H-imidazol-1-yl)-7-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1ccc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C16H13N5O/c1-10-7-11(21-6-5-17-9-21)8-13-14(10)20-15(19-13)12-3-2-4-18-16(12)22/h2-9H,1H3,(H,18,22)(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206121
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(N[C@H](CO)Cc2ccccn2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C24H23N7O2/c1-15-10-18(31-9-8-25-14-31)12-20-22(15)30-23(29-20)21-19(5-7-27-24(21)33)28-17(13-32)11-16-4-2-3-6-26-16/h2-10,12,14,17,32H,11,13H2,1H3,(H,29,30)(H2,27,28,33)/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206146
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(NCc2cccs2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C21H18N6OS/c1-13-9-14(27-7-6-22-12-27)10-17-19(13)26-20(25-17)18-16(4-5-23-21(18)28)24-11-15-3-2-8-29-15/h2-10,12H,11H2,1H3,(H,25,26)(H2,23,24,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206129
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(N[C@H](CO)Cc2ccc(Cl)cc2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C25H23ClN6O2/c1-15-10-19(32-9-8-27-14-32)12-21-23(15)31-24(30-21)22-20(6-7-28-25(22)34)29-18(13-33)11-16-2-4-17(26)5-3-16/h2-10,12,14,18,33H,11,13H2,1H3,(H,30,31)(H2,28,29,34)/t18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206131
(3-(4-((ethyl(1H-imidazol-2-yl)amino)methyl)-6-(1H-...)Show SMILES CCN(Cc1cc(cc2nc([nH]c12)-c1ccc[nH]c1=O)-n1ccnc1)c1ncc[nH]1 Show InChI InChI=1S/C21H20N8O/c1-2-28(21-24-6-7-25-21)12-14-10-15(29-9-8-22-13-29)11-17-18(14)27-19(26-17)16-4-3-5-23-20(16)30/h3-11,13H,2,12H2,1H3,(H,23,30)(H,24,25)(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206123
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(NCc2cccnc2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C22H19N7O/c1-14-9-16(29-8-7-24-13-29)10-18-20(14)28-21(27-18)19-17(4-6-25-22(19)30)26-12-15-3-2-5-23-11-15/h2-11,13H,12H2,1H3,(H,27,28)(H2,25,26,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206140
(3-(6-(1H-imidazol-1-yl)-4-((methylamino)methyl)-1H...)Show SMILES CNCc1cc(cc2nc([nH]c12)-c1ccc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C17H16N6O/c1-18-9-11-7-12(23-6-5-19-10-23)8-14-15(11)22-16(21-14)13-3-2-4-20-17(13)24/h2-8,10,18H,9H2,1H3,(H,20,24)(H,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206144
(3-(4-(aminomethyl)-6-(1H-imidazol-1-yl)-1H-benzo[d...)Show SMILES NCc1cc(cc2nc([nH]c12)-c1ccc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C16H14N6O/c17-8-10-6-11(22-5-4-18-9-22)7-13-14(10)21-15(20-13)12-2-1-3-19-16(12)23/h1-7,9H,8,17H2,(H,19,23)(H,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206137
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(NCc2ccncc2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C22H19N7O/c1-14-10-16(29-9-8-24-13-29)11-18-20(14)28-21(27-18)19-17(4-7-25-22(19)30)26-12-15-2-5-23-6-3-15/h2-11,13H,12H2,1H3,(H,27,28)(H2,25,26,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206145
(3-(6-(1H-imidazol-1-yl)-4-(piperazin-1-ylmethyl)-1...)Show SMILES O=c1[nH]cccc1-c1nc2cc(cc(CN3CCNCC3)c2[nH]1)-n1ccnc1 Show InChI InChI=1S/C20H21N7O/c28-20-16(2-1-3-23-20)19-24-17-11-15(27-9-6-22-13-27)10-14(18(17)25-19)12-26-7-4-21-5-8-26/h1-3,6,9-11,13,21H,4-5,7-8,12H2,(H,23,28)(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206138
(3-(6-(1H-imidazol-1-yl)-4-((pyridin-3-ylmethylamin...)Show SMILES O=c1[nH]cccc1-c1nc2cc(cc(CNCc3cccnc3)c2[nH]1)-n1ccnc1 Show InChI InChI=1S/C22H19N7O/c30-22-18(4-2-6-26-22)21-27-19-10-17(29-8-7-24-14-29)9-16(20(19)28-21)13-25-12-15-3-1-5-23-11-15/h1-11,14,25H,12-13H2,(H,26,30)(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206133
(3-(6-(1H-imidazol-1-yl)-4-((methyl(phenyl)amino)me...)Show SMILES CN(Cc1cc(cc2nc([nH]c12)-c1ccc[nH]c1=O)-n1ccnc1)c1ccccc1 Show InChI InChI=1S/C23H20N6O/c1-28(17-6-3-2-4-7-17)14-16-12-18(29-11-10-24-15-29)13-20-21(16)27-22(26-20)19-8-5-9-25-23(19)30/h2-13,15H,14H2,1H3,(H,25,30)(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206119
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(OCc2ccccn2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C22H18N6O2/c1-14-10-16(28-9-8-23-13-28)11-17-20(14)27-21(26-17)19-18(5-7-25-22(19)29)30-12-15-4-2-3-6-24-15/h2-11,13H,12H2,1H3,(H,25,29)(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206142
(3-(4-((benzylamino)methyl)-6-(1H-imidazol-1-yl)-1H...)Show SMILES O=c1[nH]cccc1-c1nc2cc(cc(CNCc3ccccc3)c2[nH]1)-n1ccnc1 Show InChI InChI=1S/C23H20N6O/c30-23-19(7-4-8-26-23)22-27-20-12-18(29-10-9-24-15-29)11-17(21(20)28-22)14-25-13-16-5-2-1-3-6-16/h1-12,15,25H,13-14H2,(H,26,30)(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50206149
(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1c(SCc2ccccn2)cc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C22H18N6OS/c1-14-10-16(28-9-8-23-13-28)11-17-20(14)27-21(26-17)19-18(5-7-25-22(19)29)30-12-15-4-2-3-6-24-15/h2-11,13H,12H2,1H3,(H,25,29)(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102
BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this
Ligand-Target Pair | |
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