Compile Data Set for Download or QSAR

Found 25 hits with Last Name = 'mayes' and Initial = 'ba'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426312 (US10513534, Compound 401) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1ccc(=O)[nH]c1=O |r| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent					Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...				US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426318 (US10513534, Compound 406) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C11H17ClN5O12P3/c1-11(12)7(18)5(2-26-31(22,23)29-32(24,25)28-30(19,20)21)27-10(11)17-4-16-6-8(13)14-3-15-9(6)17/h3-5,7,10,18H,2H2,1H3,(H,22,23)(H,24,25)(H2,13,14,15)(H2,19,20,21)/p-1/t5-,7-,10-,11-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent					Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...				US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426317 (US10513534, Compound 405) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1cnc2c1nc(N)[nH]c2=O |r| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent									US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426315 (US10513534, Compound 403) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1ccc2c(N)ncnc12 |r| Show InChI InChI=1S/C12H18ClN4O12P3/c1-12(13)8(18)7(4-26-31(22,23)29-32(24,25)28-30(19,20)21)27-11(12)17-3-2-6-9(14)15-5-16-10(6)17/h2-3,5,7-8,11,18H,4H2,1H3,(H,22,23)(H,24,25)(H2,14,15,16)(H2,19,20,21)/p-1/t7-,8-,11-,12-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent									US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426319 (US10513534, Compound 407) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1cc(F)c2c(N)ncnc12 |r| Show InChI InChI=1S/C12H17ClFN4O12P3/c1-12(13)8(19)6(3-27-32(23,24)30-33(25,26)29-31(20,21)22)28-11(12)18-2-5(14)7-9(15)16-4-17-10(7)18/h2,4,6,8,11,19H,3H2,1H3,(H,23,24)(H,25,26)(H2,15,16,17)(H2,20,21,22)/p-1/t6-,8-,11-,12-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent									US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepacivirus C)	BDBM50497155 (CHEMBL3291362) Show SMILES [H][C@]12OC[C@](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)(O[C@H]1n1cnc3c1nc(N)[nH]c3=O)[C@H]2O |r,THB:33:32:3.2:19.20| Show InChI InChI=1S/C11H16N5O14P3/c12-10-14-7-4(8(18)15-10)13-3-16(7)9-5-6(17)11(28-9,1-26-5)2-27-32(22,23)30-33(24,25)29-31(19,20)21/h3,5-6,9,17H,1-2H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,12,14,15,18)/t5-,6+,9-,11-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Idenix Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of purified Hepatitis C virus NS5B polymerase S282T mutant				Bioorg Med Chem Lett 24: 2699-702 (2014) Article DOI: 10.1016/j.bmcl.2014.04.050 BindingDB Entry DOI: 10.7270/Q2TM7F3N
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepacivirus C)	BDBM50497157 (CHEMBL3286448) Show SMILES C[C@]12OC[C@](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)(O[C@H]1n1cnc3c1nc(N)[nH]c3=O)[C@H]2O |r,THB:33:32:19.20:3.2| Show InChI InChI=1S/C12H18N5O14P3/c1-11-8(19)12(2-27-11,3-28-33(23,24)31-34(25,26)30-32(20,21)22)29-9(11)17-4-14-5-6(17)15-10(13)16-7(5)18/h4,8-9,19H,2-3H2,1H3,(H,23,24)(H,25,26)(H2,20,21,22)(H3,13,15,16,18)/t8-,9+,11+,12+/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Idenix Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of purified Hepatitis C virus NS5B polymerase S282T mutant				Bioorg Med Chem Lett 24: 2699-702 (2014) Article DOI: 10.1016/j.bmcl.2014.04.050 BindingDB Entry DOI: 10.7270/Q2TM7F3N
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepacivirus C)	BDBM50497158 (CHEMBL3291360) Show SMILES [H][C@]12OC[C@](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)(O[C@H]1n1ccc(N)nc1=O)[C@H]2O |r,THB:30:29:2.3:20.19| Show InChI InChI=1S/C10H16N3O14P3/c11-5-1-2-13(9(15)12-5)8-6-7(14)10(25-8,3-23-6)4-24-29(19,20)27-30(21,22)26-28(16,17)18/h1-2,6-8,14H,3-4H2,(H,19,20)(H,21,22)(H2,11,12,15)(H2,16,17,18)/t6-,7+,8-,10-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Idenix Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of purified Hepatitis C virus NS5B polymerase S282T mutant				Bioorg Med Chem Lett 24: 2699-702 (2014) Article DOI: 10.1016/j.bmcl.2014.04.050 BindingDB Entry DOI: 10.7270/Q2TM7F3N
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426314 (US10513534, Compound 402) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1ccc(N)nc1=O |r| Show InChI InChI=1S/C10H17ClN3O13P3/c1-10(11)7(15)5(25-8(10)14-3-2-6(12)13-9(14)16)4-24-29(20,21)27-30(22,23)26-28(17,18)19/h2-3,5,7-8,15H,4H2,1H3,(H,20,21)(H,22,23)(H2,12,13,16)(H2,17,18,19)/p-1/t5-,7-,8-,10-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent					Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...				US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426315 (US10513534, Compound 403) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1ccc2c(N)ncnc12 |r| Show InChI InChI=1S/C12H18ClN4O12P3/c1-12(13)8(18)7(4-26-31(22,23)29-32(24,25)28-30(19,20)21)27-11(12)17-3-2-6-9(14)15-5-16-10(6)17/h2-3,5,7-8,11,18H,4H2,1H3,(H,22,23)(H,24,25)(H2,14,15,16)(H2,19,20,21)/p-1/t7-,8-,11-,12-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent					Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...				US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426319 (US10513534, Compound 407) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1cc(F)c2c(N)ncnc12 |r| Show InChI InChI=1S/C12H17ClFN4O12P3/c1-12(13)8(19)6(3-27-32(23,24)30-33(25,26)29-31(20,21)22)28-11(12)18-2-5(14)7-9(15)16-4-17-10(7)18/h2,4,6,8,11,19H,3H2,1H3,(H,23,24)(H,25,26)(H2,15,16,17)(H2,20,21,22)/p-1/t6-,8-,11-,12-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent					Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...				US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426321 (US10513534, Compound 409) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1cc(F)c(N)nc1=O |r| Show InChI InChI=1S/C10H16ClFN3O13P3/c1-10(11)6(16)5(26-8(10)15-2-4(12)7(13)14-9(15)17)3-25-30(21,22)28-31(23,24)27-29(18,19)20/h2,5-6,8,16H,3H2,1H3,(H,21,22)(H,23,24)(H2,13,14,17)(H2,18,19,20)/p-1/t5-,6-,8-,10-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent					Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...				US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426322 (US10513534, Compound 410) Show SMILES Cc1cn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@@]2(C)Cl)c(=O)[nH]c1=O |r| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent					Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...				US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426312 (US10513534, Compound 401) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1ccc(=O)[nH]c1=O |r| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent									US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426318 (US10513534, Compound 406) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C11H17ClN5O12P3/c1-11(12)7(18)5(2-26-31(22,23)29-32(24,25)28-30(19,20)21)27-10(11)17-4-16-6-8(13)14-3-15-9(6)17/h3-5,7,10,18H,2H2,1H3,(H,22,23)(H,24,25)(H2,13,14,15)(H2,19,20,21)/p-1/t5-,7-,10-,11-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent									US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426323 (US10513534, Compound 411) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1cc(F)c(=O)[nH]c1=O |r| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent					Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...				US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426320 (US10513534, Compound 408) Show SMILES Cc1cn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP([O-])([O-])=O)[C@@H](O)[C@@]2(C)Cl)c(=O)nc1N |r| Show InChI InChI=1S/C11H19ClN3O13P3/c1-5-3-15(10(17)14-8(5)13)9-11(2,12)7(16)6(26-9)4-25-30(21,22)28-31(23,24)27-29(18,19)20/h3,6-7,9,16H,4H2,1-2H3,(H,21,22)(H,23,24)(H2,13,14,17)(H2,18,19,20)/p-2/t6-,7-,9-,11-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent					Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...				US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426317 (US10513534, Compound 405) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O[C@H]1n1cnc2c1nc(N)[nH]c2=O |r| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent					Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...				US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426316 (US10513534, Compound 404) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)O[C@H]1n1cnc2c(N)nc(Cl)nc12 |r| Show InChI InChI=1S/C11H16Cl2N5O12P3/c1-11(13)6(19)4(2-27-32(23,24)30-33(25,26)29-31(20,21)22)28-9(11)18-3-15-5-7(14)16-10(12)17-8(5)18/h3-4,6,9,19H,2H2,1H3,(H,23,24)(H,25,26)(H2,14,16,17)(H2,20,21,22)/p-2/t4-,6-,9-,11-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent									US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM426316 (US10513534, Compound 404) Show SMILES C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)O[C@H]1n1cnc2c(N)nc(Cl)nc12 |r| Show InChI InChI=1S/C11H16Cl2N5O12P3/c1-11(13)6(19)4(2-27-32(23,24)30-33(25,26)29-31(20,21)22)28-9(11)18-3-15-5-7(14)16-10(12)17-8(5)18/h3-4,6,9,19H,2H2,1H3,(H,23,24)(H,25,26)(H2,14,16,17)(H2,20,21,22)/p-2/t4-,6-,9-,11-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent					Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...				US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepacivirus C)	BDBM50497159 (CHEMBL3291361) Show SMILES [H][C@]12OC[C@](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)(O[C@H]1n1ccc(=O)[nH]c1=O)[C@H]2O |r,THB:30:29:2.3:20.19| Show InChI InChI=1S/C10H15N2O15P3/c13-5-1-2-12(9(15)11-5)8-6-7(14)10(25-8,3-23-6)4-24-29(19,20)27-30(21,22)26-28(16,17)18/h1-2,6-8,14H,3-4H2,(H,19,20)(H,21,22)(H,11,13,15)(H2,16,17,18)/t6-,7+,8-,10-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
Idenix Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of purified Hepatitis C virus NS5B polymerase S282T mutant				Bioorg Med Chem Lett 24: 2699-702 (2014) Article DOI: 10.1016/j.bmcl.2014.04.050 BindingDB Entry DOI: 10.7270/Q2TM7F3N
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepacivirus C)	BDBM50497154 (CHEMBL3286449) Show SMILES [H][C@]12OC[C@@](O[C@H]1n1cnc3c1nc(N)[nH]c3=O)(C(C)OP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@H]2O |r,THB:34:33:2.3:6.5| Show InChI InChI=1S/C12H18N5O14P3/c1-4(29-33(23,24)31-34(25,26)30-32(20,21)22)12-2-27-6(7(12)18)10(28-12)17-3-14-5-8(17)15-11(13)16-9(5)19/h3-4,6-7,10,18H,2H2,1H3,(H,23,24)(H,25,26)(H2,20,21,22)(H3,13,15,16,19)/t4?,6-,7+,10-,12-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Idenix Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of purified Hepatitis C virus NS5B polymerase S282T mutant				Bioorg Med Chem Lett 24: 2699-702 (2014) Article DOI: 10.1016/j.bmcl.2014.04.050 BindingDB Entry DOI: 10.7270/Q2TM7F3N
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepacivirus C)	BDBM50497153 (CHEMBL3291359) Show SMILES [H][C@]12OC[C@](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)(O[C@H]1n1cnc3c(N)ncnc13)[C@H]2O |r,THB:32:31:2.3:20.19| Show InChI InChI=1S/C11H16N5O13P3/c12-8-5-9(14-3-13-8)16(4-15-5)10-6-7(17)11(27-10,1-25-6)2-26-31(21,22)29-32(23,24)28-30(18,19)20/h3-4,6-7,10,17H,1-2H2,(H,21,22)(H,23,24)(H2,12,13,14)(H2,18,19,20)/t6-,7+,10-,11-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Idenix Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of purified Hepatitis C virus NS5B polymerase S282T mutant				Bioorg Med Chem Lett 24: 2699-702 (2014) Article DOI: 10.1016/j.bmcl.2014.04.050 BindingDB Entry DOI: 10.7270/Q2TM7F3N
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepacivirus C)	BDBM50497156 (CHEMBL3291363) Show SMILES [H][C@]12OCC[C@](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)(O[C@H]1n1cnc3c1nc(N)[nH]c3=O)[C@H]2O |r,THB:34:33:2.3.4:21.20| Show InChI InChI=1S/C12H18N5O14P3/c13-11-15-8-5(9(19)16-11)14-4-17(8)10-6-7(18)12(29-10,1-2-27-6)3-28-33(23,24)31-34(25,26)30-32(20,21)22/h4,6-7,10,18H,1-3H2,(H,23,24)(H,25,26)(H2,20,21,22)(H3,13,15,16,19)/t6-,7+,10-,12-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Idenix Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of purified Hepatitis C virus NS5B polymerase S282T mutant				Bioorg Med Chem Lett 24: 2699-702 (2014) Article DOI: 10.1016/j.bmcl.2014.04.050 BindingDB Entry DOI: 10.7270/Q2TM7F3N
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepacivirus C)	BDBM50497154 (CHEMBL3286449) Show SMILES [H][C@]12OC[C@@](O[C@H]1n1cnc3c1nc(N)[nH]c3=O)(C(C)OP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@H]2O |r,THB:34:33:2.3:6.5| Show InChI InChI=1S/C12H18N5O14P3/c1-4(29-33(23,24)31-34(25,26)30-32(20,21)22)12-2-27-6(7(12)18)10(28-12)17-3-14-5-8(17)15-11(13)16-9(5)19/h3-4,6-7,10,18H,2H2,1H3,(H,23,24)(H,25,26)(H2,20,21,22)(H3,13,15,16,19)/t4?,6-,7+,10-,12-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Idenix Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of purified Hepatitis C virus NS5B polymerase S282T mutant				Bioorg Med Chem Lett 24: 2699-702 (2014) Article DOI: 10.1016/j.bmcl.2014.04.050 BindingDB Entry DOI: 10.7270/Q2TM7F3N
					More data for this Ligand-Target Pair