Compile Data Set for Download or QSAR

Found 84 hits with Last Name = 'evison' and Initial = 'bj'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50237710 (4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F Show InChI InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged Abl (2 to 1130 residues) expressed in baculovirus expression system using FAM-labelled P2 pepti...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50237710 (4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F Show InChI InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544961 (CHEMBL4632839) Show SMILES CN1CCN(CC1)c1cccc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 Show InChI InChI=1S/C29H29FN6O/c1-20-6-7-22(28(37)32-24-4-3-5-25(19-24)36-16-14-35(2)15-17-36)18-27(20)34-29-31-13-12-26(33-29)21-8-10-23(30)11-9-21/h3-13,18-19H,14-17H2,1-2H3,(H,32,37)(H,31,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50544967 (CHEMBL4633069) Show SMILES CCCCc1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccccc3)c2)cc(c1)-n1cnc(C)c1 Show InChI InChI=1S/C32H32N6O/c1-4-5-9-24-16-27(19-28(17-24)38-20-23(3)34-21-38)35-31(39)26-13-12-22(2)30(18-26)37-32-33-15-14-29(36-32)25-10-7-6-8-11-25/h6-8,10-21H,4-5,9H2,1-3H3,(H,35,39)(H,33,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged Abl (2 to 1130 residues) expressed in baculovirus expression system using FAM-labelled P2 pepti...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50237710 (4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F Show InChI InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544978 (CHEMBL4638350) Show SMILES CN1CCN(CC1)c1cc(NC(=O)c2ccc(C)c(Oc3cccc4ccncc34)c2)cc(c1)-n1cnc(C)c1 Show InChI InChI=1S/C32H32N6O2/c1-22-7-8-25(15-31(22)40-30-6-4-5-24-9-10-33-19-29(24)30)32(39)35-26-16-27(37-13-11-36(3)12-14-37)18-28(17-26)38-20-23(2)34-21-38/h4-10,15-21H,11-14H2,1-3H3,(H,35,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	227	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544967 (CHEMBL4633069) Show SMILES CCCCc1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccccc3)c2)cc(c1)-n1cnc(C)c1 Show InChI InChI=1S/C32H32N6O/c1-4-5-9-24-16-27(19-28(17-24)38-20-23(3)34-21-38)35-31(39)26-13-12-22(2)30(18-26)37-32-33-15-14-29(36-32)25-10-7-6-8-11-25/h6-8,10-21H,4-5,9H2,1-3H3,(H,35,39)(H,33,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	302	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50544974 (CHEMBL4642181) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccccc3)c2)cc(c1)C(F)(F)F Show InChI InChI=1S/C29H23F3N6O/c1-18-8-9-21(12-26(18)37-28-33-11-10-25(36-28)20-6-4-3-5-7-20)27(39)35-23-13-22(29(30,31)32)14-24(15-23)38-16-19(2)34-17-38/h3-17H,1-2H3,(H,35,39)(H,33,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	334	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged Abl (2 to 1130 residues) expressed in baculovirus expression system using FAM-labelled P2 pepti...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544969 (CHEMBL4637172) Show SMILES Cc1cn(cn1)-c1cc(CCC(O)=O)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccccc3)c2)c1 Show InChI InChI=1S/C31H28N6O3/c1-20-8-10-24(16-28(20)36-31-32-13-12-27(35-31)23-6-4-3-5-7-23)30(40)34-25-14-22(9-11-29(38)39)15-26(17-25)37-18-21(2)33-19-37/h3-8,10,12-19H,9,11H2,1-2H3,(H,34,40)(H,38,39)(H,32,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	347	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544974 (CHEMBL4642181) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccccc3)c2)cc(c1)C(F)(F)F Show InChI InChI=1S/C29H23F3N6O/c1-18-8-9-21(12-26(18)37-28-33-11-10-25(36-28)20-6-4-3-5-7-20)27(39)35-23-13-22(29(30,31)32)14-24(15-23)38-16-19(2)34-17-38/h3-17H,1-2H3,(H,35,39)(H,33,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	592	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544975 (CHEMBL4638092) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Oc3ccccc3)c2)cc(c1)C(F)(F)F Show InChI InChI=1S/C25H20F3N3O2/c1-16-8-9-18(10-23(16)33-22-6-4-3-5-7-22)24(32)30-20-11-19(25(26,27)28)12-21(13-20)31-14-17(2)29-15-31/h3-15H,1-2H3,(H,30,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	618	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544963 (CHEMBL4638611) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)cc(c1)N1CCOCC1 Show InChI InChI=1S/C32H30FN7O2/c1-21-3-4-24(15-30(21)38-32-34-10-9-29(37-32)23-5-7-25(33)8-6-23)31(41)36-26-16-27(39-11-13-42-14-12-39)18-28(17-26)40-19-22(2)35-20-40/h3-10,15-20H,11-14H2,1-2H3,(H,36,41)(H,34,37,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544973 (CHEMBL4638783) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccccc3)c2)cc(c1)N1CCNCC1 Show InChI InChI=1S/C32H32N8O/c1-22-8-9-25(16-30(22)38-32-34-11-10-29(37-32)24-6-4-3-5-7-24)31(41)36-26-17-27(39-14-12-33-13-15-39)19-28(18-26)40-20-23(2)35-21-40/h3-11,16-21,33H,12-15H2,1-2H3,(H,36,41)(H,34,37,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50544973 (CHEMBL4638783) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccccc3)c2)cc(c1)N1CCNCC1 Show InChI InChI=1S/C32H32N8O/c1-22-8-9-25(16-30(22)38-32-34-11-10-29(37-32)24-6-4-3-5-7-24)31(41)36-26-17-27(39-14-12-33-13-15-39)19-28(18-26)40-20-23(2)35-21-40/h3-11,16-21,33H,12-15H2,1-2H3,(H,36,41)(H,34,37,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50237710 (4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F Show InChI InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-tagged SRC (1 to 536 residues) expressed in baculovirus expression system using FAM-labell...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544966 (CHEMBL4637487) Show SMILES Cc1cn(cn1)-c1cc(CN2CCC[C@H](N)C2)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 |r| Show InChI InChI=1S/C34H35FN8O/c1-22-5-6-26(16-32(22)41-34-37-12-11-31(40-34)25-7-9-27(35)10-8-25)33(44)39-29-14-24(19-42-13-3-4-28(36)20-42)15-30(17-29)43-18-23(2)38-21-43/h5-12,14-18,21,28H,3-4,13,19-20,36H2,1-2H3,(H,39,44)(H,37,40,41)/t28-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50544966 (CHEMBL4637487) Show SMILES Cc1cn(cn1)-c1cc(CN2CCC[C@H](N)C2)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 |r| Show InChI InChI=1S/C34H35FN8O/c1-22-5-6-26(16-32(22)41-34-37-12-11-31(40-34)25-7-9-27(35)10-8-25)33(44)39-29-14-24(19-42-13-3-4-28(36)20-42)15-30(17-29)43-18-23(2)38-21-43/h5-12,14-18,21,28H,3-4,13,19-20,36H2,1-2H3,(H,39,44)(H,37,40,41)/t28-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50544974 (CHEMBL4642181) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccccc3)c2)cc(c1)C(F)(F)F Show InChI InChI=1S/C29H23F3N6O/c1-18-8-9-21(12-26(18)37-28-33-11-10-25(36-28)20-6-4-3-5-7-20)27(39)35-23-13-22(29(30,31)32)14-24(15-23)38-16-19(2)34-17-38/h3-17H,1-2H3,(H,35,39)(H,33,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544971 (CHEMBL4635318) Show SMILES CN1CCN(Cc2cc(NC(=O)c3ccc(C)c(Nc4nccc(n4)-c4ccccc4)c3)cc(c2)-n2cnc(C)c2)CC1 Show InChI InChI=1S/C34H36N8O/c1-24-9-10-28(19-32(24)39-34-35-12-11-31(38-34)27-7-5-4-6-8-27)33(43)37-29-17-26(22-41-15-13-40(3)14-16-41)18-30(20-29)42-21-25(2)36-23-42/h4-12,17-21,23H,13-16,22H2,1-3H3,(H,37,43)(H,35,38,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50544978 (CHEMBL4638350) Show SMILES CN1CCN(CC1)c1cc(NC(=O)c2ccc(C)c(Oc3cccc4ccncc34)c2)cc(c1)-n1cnc(C)c1 Show InChI InChI=1S/C32H32N6O2/c1-22-7-8-25(15-31(22)40-30-6-4-5-24-9-10-33-19-29(24)30)32(39)35-26-16-27(37-13-11-36(3)12-14-37)18-28(17-26)38-20-23(2)34-21-38/h4-10,15-21H,11-14H2,1-3H3,(H,35,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-tagged SRC (1 to 536 residues) expressed in baculovirus expression system using FAM-labell...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544970 (CHEMBL4642089) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccccc3)c2)cc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C31H26N6O3/c1-20-8-10-24(16-28(20)36-31-32-13-12-27(35-31)23-6-4-3-5-7-23)30(40)34-25-14-22(9-11-29(38)39)15-26(17-25)37-18-21(2)33-19-37/h3-19H,1-2H3,(H,34,40)(H,38,39)(H,32,35,36)/b11-9+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544972 (CHEMBL4642128) Show SMILES CN1CCN(CC1)c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccccc3)c2)cc(c1)-n1cnc(C)c1 Show InChI InChI=1S/C33H34N8O/c1-23-9-10-26(17-31(23)38-33-34-12-11-30(37-33)25-7-5-4-6-8-25)32(42)36-27-18-28(40-15-13-39(3)14-16-40)20-29(19-27)41-21-24(2)35-22-41/h4-12,17-22H,13-16H2,1-3H3,(H,36,42)(H,34,37,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544962 (CHEMBL4648729) Show SMILES CN1CCN(CC1)c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)cc(c1)-c1cc(C)no1 Show InChI InChI=1S/C33H32FN7O2/c1-21-4-5-24(19-30(21)38-33-35-11-10-29(37-33)23-6-8-26(34)9-7-23)32(42)36-27-17-25(31-16-22(2)39-43-31)18-28(20-27)41-14-12-40(3)13-15-41/h4-11,16-20H,12-15H2,1-3H3,(H,36,42)(H,35,37,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50544978 (CHEMBL4638350) Show SMILES CN1CCN(CC1)c1cc(NC(=O)c2ccc(C)c(Oc3cccc4ccncc34)c2)cc(c1)-n1cnc(C)c1 Show InChI InChI=1S/C32H32N6O2/c1-22-7-8-25(15-31(22)40-30-6-4-5-24-9-10-33-19-29(24)30)32(39)35-26-16-27(37-13-11-36(3)12-14-37)18-28(17-26)38-20-23(2)34-21-38/h4-10,15-21H,11-14H2,1-3H3,(H,35,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50544973 (CHEMBL4638783) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccccc3)c2)cc(c1)N1CCNCC1 Show InChI InChI=1S/C32H32N8O/c1-22-8-9-25(16-30(22)38-32-34-11-10-29(37-32)24-6-4-3-5-7-24)31(41)36-26-17-27(39-14-12-33-13-15-39)19-28(18-26)40-20-23(2)35-21-40/h3-11,16-21,33H,12-15H2,1-2H3,(H,36,41)(H,34,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-tagged SRC (1 to 536 residues) expressed in baculovirus expression system using FAM-labell...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50544971 (CHEMBL4635318) Show SMILES CN1CCN(Cc2cc(NC(=O)c3ccc(C)c(Nc4nccc(n4)-c4ccccc4)c3)cc(c2)-n2cnc(C)c2)CC1 Show InChI InChI=1S/C34H36N8O/c1-24-9-10-28(19-32(24)39-34-35-12-11-31(38-34)27-7-5-4-6-8-27)33(43)37-29-17-26(22-41-15-13-40(3)14-16-41)18-30(20-29)42-21-25(2)36-23-42/h4-12,17-21,23H,13-16,22H2,1-3H3,(H,37,43)(H,35,38,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50544962 (CHEMBL4648729) Show SMILES CN1CCN(CC1)c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)cc(c1)-c1cc(C)no1 Show InChI InChI=1S/C33H32FN7O2/c1-21-4-5-24(19-30(21)38-33-35-11-10-29(37-33)23-6-8-26(34)9-7-23)32(42)36-27-17-25(31-16-22(2)39-43-31)18-28(20-27)41-14-12-40(3)13-15-41/h4-11,16-20H,12-15H2,1-3H3,(H,36,42)(H,35,37,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544968 (CHEMBL4642587) Show SMILES Cc1cn(cn1)-c1cc(CCS(N)(=O)=O)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccccc3)c2)c1 Show InChI InChI=1S/C30H29N7O3S/c1-20-8-9-24(16-28(20)36-30-32-12-10-27(35-30)23-6-4-3-5-7-23)29(38)34-25-14-22(11-13-41(31,39)40)15-26(17-25)37-18-21(2)33-19-37/h3-10,12,14-19H,11,13H2,1-2H3,(H,34,38)(H2,31,39,40)(H,32,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50544977 (CHEMBL4649103) Show SMILES CN1CCN(CC1)c1cc(NC(=O)c2ccc(C)c(Oc3ccccc3)c2)cc(c1)-n1cnc(C)c1 Show InChI InChI=1S/C29H31N5O2/c1-21-9-10-23(15-28(21)36-27-7-5-4-6-8-27)29(35)31-24-16-25(33-13-11-32(3)12-14-33)18-26(17-24)34-19-22(2)30-20-34/h4-10,15-20H,11-14H2,1-3H3,(H,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50544973 (CHEMBL4638783) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccccc3)c2)cc(c1)N1CCNCC1 Show InChI InChI=1S/C32H32N8O/c1-22-8-9-25(16-30(22)38-32-34-11-10-29(37-32)24-6-4-3-5-7-24)31(41)36-26-17-27(39-14-12-33-13-15-39)19-28(18-26)40-20-23(2)35-21-40/h3-11,16-21,33H,12-15H2,1-2H3,(H,36,41)(H,34,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged Abl (2 to 1130 residues) expressed in baculovirus expression system using FAM-labelled P2 pepti...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544964 (CHEMBL4646469) Show SMILES Cc1cn(cn1)-c1cc(CN2CCCC[C@H]2C(N)=O)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 |r| Show InChI InChI=1S/C35H35FN8O2/c1-22-6-7-26(17-31(22)42-35-38-13-12-30(41-35)25-8-10-27(36)11-9-25)34(46)40-28-15-24(16-29(18-28)44-19-23(2)39-21-44)20-43-14-4-3-5-32(43)33(37)45/h6-13,15-19,21,32H,3-5,14,20H2,1-2H3,(H2,37,45)(H,40,46)(H,38,41,42)/t32-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50544980 (CHEMBL4643586) Show SMILES Cc1cn(cn1)-c1cc(CN2CCC[C@H](N)C2)cc(NC(=O)c2ccc(C)c(Oc3ccccc3)c2)c1 |r| Show InChI InChI=1S/C30H33N5O2/c1-21-10-11-24(15-29(21)37-28-8-4-3-5-9-28)30(36)33-26-13-23(18-34-12-6-7-25(31)19-34)14-27(16-26)35-17-22(2)32-20-35/h3-5,8-11,13-17,20,25H,6-7,12,18-19,31H2,1-2H3,(H,33,36)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50544961 (CHEMBL4632839) Show SMILES CN1CCN(CC1)c1cccc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 Show InChI InChI=1S/C29H29FN6O/c1-20-6-7-22(28(37)32-24-4-3-5-25(19-24)36-16-14-35(2)15-17-36)18-27(20)34-29-31-13-12-26(33-29)21-8-10-23(30)11-9-21/h3-13,18-19H,14-17H2,1-2H3,(H,32,37)(H,31,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-tagged SRC (1 to 536 residues) expressed in baculovirus expression system using FAM-labell...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50544962 (CHEMBL4648729) Show SMILES CN1CCN(CC1)c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)cc(c1)-c1cc(C)no1 Show InChI InChI=1S/C33H32FN7O2/c1-21-4-5-24(19-30(21)38-33-35-11-10-29(37-33)23-6-8-26(34)9-7-23)32(42)36-27-17-25(31-16-22(2)39-43-31)18-28(20-27)41-14-12-40(3)13-15-41/h4-11,16-20H,12-15H2,1-3H3,(H,36,42)(H,35,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-tagged SRC (1 to 536 residues) expressed in baculovirus expression system using FAM-labell...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50544963 (CHEMBL4638611) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)cc(c1)N1CCOCC1 Show InChI InChI=1S/C32H30FN7O2/c1-21-3-4-24(15-30(21)38-32-34-10-9-29(37-32)23-5-7-25(33)8-6-23)31(41)36-26-16-27(39-11-13-42-14-12-39)18-28(17-26)40-19-22(2)35-20-40/h3-10,15-20H,11-14H2,1-2H3,(H,36,41)(H,34,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-tagged SRC (1 to 536 residues) expressed in baculovirus expression system using FAM-labell...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50544964 (CHEMBL4646469) Show SMILES Cc1cn(cn1)-c1cc(CN2CCCC[C@H]2C(N)=O)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 |r| Show InChI InChI=1S/C35H35FN8O2/c1-22-6-7-26(17-31(22)42-35-38-13-12-30(41-35)25-8-10-27(36)11-9-25)34(46)40-28-15-24(16-29(18-28)44-19-23(2)39-21-44)20-43-14-4-3-5-32(43)33(37)45/h6-13,15-19,21,32H,3-5,14,20H2,1-2H3,(H2,37,45)(H,40,46)(H,38,41,42)/t32-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-tagged SRC (1 to 536 residues) expressed in baculovirus expression system using FAM-labell...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50544965 (CHEMBL4639891) Show SMILES Cc1cn(cn1)-c1cc(CN2CCCC[C@H]2C(O)=O)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 |r| Show InChI InChI=1S/C35H34FN7O3/c1-22-6-7-26(17-31(22)41-35-37-13-12-30(40-35)25-8-10-27(36)11-9-25)33(44)39-28-15-24(16-29(18-28)43-19-23(2)38-21-43)20-42-14-4-3-5-32(42)34(45)46/h6-13,15-19,21,32H,3-5,14,20H2,1-2H3,(H,39,44)(H,45,46)(H,37,40,41)/t32-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-tagged SRC (1 to 536 residues) expressed in baculovirus expression system using FAM-labell...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50544966 (CHEMBL4637487) Show SMILES Cc1cn(cn1)-c1cc(CN2CCC[C@H](N)C2)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 |r| Show InChI InChI=1S/C34H35FN8O/c1-22-5-6-26(16-32(22)41-34-37-12-11-31(40-34)25-7-9-27(35)10-8-25)33(44)39-29-14-24(19-42-13-3-4-28(36)20-42)15-30(17-29)43-18-23(2)38-21-43/h5-12,14-18,21,28H,3-4,13,19-20,36H2,1-2H3,(H,39,44)(H,37,40,41)/t28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-tagged SRC (1 to 536 residues) expressed in baculovirus expression system using FAM-labell...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50544961 (CHEMBL4632839) Show SMILES CN1CCN(CC1)c1cccc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 Show InChI InChI=1S/C29H29FN6O/c1-20-6-7-22(28(37)32-24-4-3-5-25(19-24)36-16-14-35(2)15-17-36)18-27(20)34-29-31-13-12-26(33-29)21-8-10-23(30)11-9-21/h3-13,18-19H,14-17H2,1-2H3,(H,32,37)(H,31,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50544963 (CHEMBL4638611) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)cc(c1)N1CCOCC1 Show InChI InChI=1S/C32H30FN7O2/c1-21-3-4-24(15-30(21)38-32-34-10-9-29(37-32)23-5-7-25(33)8-6-23)31(41)36-26-16-27(39-11-13-42-14-12-39)18-28(17-26)40-19-22(2)35-20-40/h3-10,15-20H,11-14H2,1-2H3,(H,36,41)(H,34,37,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50544964 (CHEMBL4646469) Show SMILES Cc1cn(cn1)-c1cc(CN2CCCC[C@H]2C(N)=O)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 |r| Show InChI InChI=1S/C35H35FN8O2/c1-22-6-7-26(17-31(22)42-35-38-13-12-30(41-35)25-8-10-27(36)11-9-25)34(46)40-28-15-24(16-29(18-28)44-19-23(2)39-21-44)20-43-14-4-3-5-32(43)33(37)45/h6-13,15-19,21,32H,3-5,14,20H2,1-2H3,(H2,37,45)(H,40,46)(H,38,41,42)/t32-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50544965 (CHEMBL4639891) Show SMILES Cc1cn(cn1)-c1cc(CN2CCCC[C@H]2C(O)=O)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 |r| Show InChI InChI=1S/C35H34FN7O3/c1-22-6-7-26(17-31(22)41-35-37-13-12-30(40-35)25-8-10-27(36)11-9-25)33(44)39-28-15-24(16-29(18-28)43-19-23(2)38-21-43)20-42-14-4-3-5-32(42)34(45)46/h6-13,15-19,21,32H,3-5,14,20H2,1-2H3,(H,39,44)(H,45,46)(H,37,40,41)/t32-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50544961 (CHEMBL4632839) Show SMILES CN1CCN(CC1)c1cccc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 Show InChI InChI=1S/C29H29FN6O/c1-20-6-7-22(28(37)32-24-4-3-5-25(19-24)36-16-14-35(2)15-17-36)18-27(20)34-29-31-13-12-26(33-29)21-8-10-23(30)11-9-21/h3-13,18-19H,14-17H2,1-2H3,(H,32,37)(H,31,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged Abl (2 to 1130 residues) expressed in baculovirus expression system using FAM-labelled P2 pepti...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50544962 (CHEMBL4648729) Show SMILES CN1CCN(CC1)c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)cc(c1)-c1cc(C)no1 Show InChI InChI=1S/C33H32FN7O2/c1-21-4-5-24(19-30(21)38-33-35-11-10-29(37-33)23-6-8-26(34)9-7-23)32(42)36-27-17-25(31-16-22(2)39-43-31)18-28(20-27)41-14-12-40(3)13-15-41/h4-11,16-20H,12-15H2,1-3H3,(H,36,42)(H,35,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged Abl (2 to 1130 residues) expressed in baculovirus expression system using FAM-labelled P2 pepti...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50544963 (CHEMBL4638611) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)cc(c1)N1CCOCC1 Show InChI InChI=1S/C32H30FN7O2/c1-21-3-4-24(15-30(21)38-32-34-10-9-29(37-32)23-5-7-25(33)8-6-23)31(41)36-26-16-27(39-11-13-42-14-12-39)18-28(17-26)40-19-22(2)35-20-40/h3-10,15-20H,11-14H2,1-2H3,(H,36,41)(H,34,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged Abl (2 to 1130 residues) expressed in baculovirus expression system using FAM-labelled P2 pepti...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50544964 (CHEMBL4646469) Show SMILES Cc1cn(cn1)-c1cc(CN2CCCC[C@H]2C(N)=O)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 |r| Show InChI InChI=1S/C35H35FN8O2/c1-22-6-7-26(17-31(22)42-35-38-13-12-30(41-35)25-8-10-27(36)11-9-25)34(46)40-28-15-24(16-29(18-28)44-19-23(2)39-21-44)20-43-14-4-3-5-32(43)33(37)45/h6-13,15-19,21,32H,3-5,14,20H2,1-2H3,(H2,37,45)(H,40,46)(H,38,41,42)/t32-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged Abl (2 to 1130 residues) expressed in baculovirus expression system using FAM-labelled P2 pepti...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50544965 (CHEMBL4639891) Show SMILES Cc1cn(cn1)-c1cc(CN2CCCC[C@H]2C(O)=O)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 |r| Show InChI InChI=1S/C35H34FN7O3/c1-22-6-7-26(17-31(22)41-35-37-13-12-30(40-35)25-8-10-27(36)11-9-25)33(44)39-28-15-24(16-29(18-28)43-19-23(2)38-21-43)20-42-14-4-3-5-32(42)34(45)46/h6-13,15-19,21,32H,3-5,14,20H2,1-2H3,(H,39,44)(H,45,46)(H,37,40,41)/t32-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged Abl (2 to 1130 residues) expressed in baculovirus expression system using FAM-labelled P2 pepti...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50544966 (CHEMBL4637487) Show SMILES Cc1cn(cn1)-c1cc(CN2CCC[C@H](N)C2)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 |r| Show InChI InChI=1S/C34H35FN8O/c1-22-5-6-26(16-32(22)41-34-37-12-11-31(40-34)25-7-9-27(35)10-8-25)33(44)39-29-14-24(19-42-13-3-4-28(36)20-42)15-30(17-29)43-18-23(2)38-21-43/h5-12,14-18,21,28H,3-4,13,19-20,36H2,1-2H3,(H,39,44)(H,37,40,41)/t28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged Abl (2 to 1130 residues) expressed in baculovirus expression system using FAM-labelled P2 pepti...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50544965 (CHEMBL4639891) Show SMILES Cc1cn(cn1)-c1cc(CN2CCCC[C@H]2C(O)=O)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccc(F)cc3)c2)c1 |r| Show InChI InChI=1S/C35H34FN7O3/c1-22-6-7-26(17-31(22)41-35-37-13-12-30(40-35)25-8-10-27(36)11-9-25)33(44)39-28-15-24(16-29(18-28)43-19-23(2)38-21-43)20-42-14-4-3-5-32(42)34(45)46/h6-13,15-19,21,32H,3-5,14,20H2,1-2H3,(H,39,44)(H,45,46)(H,37,40,41)/t32-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged c-Kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-label...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50544967 (CHEMBL4633069) Show SMILES CCCCc1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3ccccc3)c2)cc(c1)-n1cnc(C)c1 Show InChI InChI=1S/C32H32N6O/c1-4-5-9-24-16-27(19-28(17-24)38-20-23(3)34-21-38)35-31(39)26-13-12-22(2)30(18-26)37-32-33-15-14-29(36-32)25-10-7-6-8-11-25/h6-8,10-21H,4-5,9H2,1-3H3,(H,35,39)(H,33,36,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nyrada Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-tagged SRC (1 to 536 residues) expressed in baculovirus expression system using FAM-labell...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115344 BindingDB Entry DOI: 10.7270/Q2Z89H0P
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 84 total )  |  Next  |  Last  >>

Jump to: