Found 10 hits with Last Name = 'koerner' and Initial = 'c' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50105838
(FENOBAM)Show InChI InChI=1S/C11H11ClN4O2/c1-16-6-9(17)14-10(16)15-11(18)13-8-4-2-3-7(12)5-8/h2-5H,6H2,1H3,(H2,13,14,15,17,18) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50105838
(FENOBAM)Show InChI InChI=1S/C11H11ClN4O2/c1-16-6-9(17)14-10(16)15-11(18)13-8-4-2-3-7(12)5-8/h2-5H,6H2,1H3,(H2,13,14,15,17,18) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450061
(CHEMBL4166199)Show InChI InChI=1S/C13H11N3O2/c1-8-3-5-10(6-4-8)16-13(17)12-11(7-18-15-12)9(2)14-16/h3-7H,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450078
(CHEMBL4167825)Show InChI InChI=1S/C12H7Cl2N3O2/c1-6-10-5-19-16-11(10)12(18)17(15-6)9-3-7(13)2-8(14)4-9/h2-5H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450077
(CHEMBL4164391)Show SMILES Cc1nn(-c2ccc(cc2)[N+]([O-])=O)c(=O)c2nocc12 Show InChI InChI=1S/C12H8N4O4/c1-7-10-6-20-14-11(10)12(17)15(13-7)8-2-4-9(5-3-8)16(18)19/h2-6H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450076
(CHEMBL4163974)Show InChI InChI=1S/C12H7F2N3O2/c1-6-8-5-19-16-11(8)12(18)17(15-6)10-3-2-7(13)4-9(10)14/h2-5H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450074
(CHEMBL4171187)Show InChI InChI=1S/C13H11N3O3/c1-8-11-7-19-15-12(11)13(17)16(14-8)9-3-5-10(18-2)6-4-9/h3-7H,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450060
(CHEMBL4172276)Show SMILES Cc1nn(-c2cccc(c2)[N+]([O-])=O)c(=O)c2nocc12 Show InChI InChI=1S/C12H8N4O4/c1-7-10-6-20-14-11(10)12(17)15(13-7)8-3-2-4-9(5-8)16(18)19/h2-6H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450059
(CHEMBL4160584)Show InChI InChI=1S/C12H8FN3O2/c1-7-10-6-18-15-11(10)12(17)16(14-7)9-4-2-8(13)3-5-9/h2-6H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450075
(CHEMBL4174628)Show InChI InChI=1S/C12H9N3O2/c1-8-10-7-17-14-11(10)12(16)15(13-8)9-5-3-2-4-6-9/h2-7H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |