Compile Data Set for Download or QSAR

Found 50 hits with Last Name = 'burkhart' and Initial = 'ca'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50015711 (3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indole-5-ca...) Show SMILES N#Cc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:9| Show InChI InChI=1S/C14H13N3/c15-8-10-1-2-14-12(7-10)13(9-17-14)11-3-5-16-6-4-11/h1-3,7,9,16-17H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50015714 (3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indol-5-ol ...) Show SMILES Oc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:8| Show InChI InChI=1S/C13H14N2O/c16-10-1-2-13-11(7-10)12(8-15-13)9-3-5-14-6-4-9/h1-3,7-8,14-16H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50015712 (5-Fluoro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-in...) Show SMILES Fc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:8| Show InChI InChI=1S/C13H13FN2/c14-10-1-2-13-11(7-10)12(8-16-13)9-3-5-15-6-4-9/h1-3,7-8,15-16H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM81498 (5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...) Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:9| Show InChI InChI=1S/C14H16N2O/c1-17-11-2-3-14-12(8-11)13(9-16-14)10-4-6-15-7-5-10/h2-4,8-9,15-16H,5-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligand				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50015709 (5-Bromo-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-ind...) Show SMILES Brc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:8| Show InChI InChI=1S/C13H13BrN2/c14-10-1-2-13-11(7-10)12(8-16-13)9-3-5-15-6-4-9/h1-3,7-8,15-16H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50015717 (5-Chloro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-in...) Show SMILES Clc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:8| Show InChI InChI=1S/C13H13ClN2/c14-10-1-2-13-11(7-10)12(8-16-13)9-3-5-15-6-4-9/h1-3,7-8,15-16H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50015718 (5-Nitro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-ind...) Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:10| Show InChI InChI=1S/C13H13N3O2/c17-16(18)10-1-2-13-11(7-10)12(8-15-13)9-3-5-14-6-4-9/h1-3,7-8,14-15H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM31023 (3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...) Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12 |c:2| Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT as the radioligand.				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT as the radioligand.				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptor				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50015709 (5-Bromo-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-ind...) Show SMILES Brc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:8| Show InChI InChI=1S/C13H13BrN2/c14-10-1-2-13-11(7-10)12(8-16-13)9-3-5-15-6-4-9/h1-3,7-8,15-16H,4-6H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptor				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM81498 (5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...) Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:9| Show InChI InChI=1S/C14H16N2O/c1-17-11-2-3-14-12(8-11)13(9-16-14)10-4-6-15-7-5-10/h2-4,8-9,15-16H,5-7H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptor				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM84737 (3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...) Show SMILES O=c1ccc2[nH]cc(C3=CCNCC3)c2[nH]1 |t:8| Show InChI InChI=1S/C12H11N3O/c16-11-2-1-10-12(15-11)9(7-14-10)8-3-5-13-6-4-8/h1-3,7,13H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]5-HT				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM81497 (4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrr...) Show SMILES CN1CCN(CC1)c1nc2cc(ccc2n2cccc12)C(F)(F)F Show InChI InChI=1S/C17H17F3N4/c1-22-7-9-23(10-8-22)16-15-3-2-6-24(15)14-5-4-12(17(18,19)20)11-13(14)21-16/h2-6,11H,7-10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptor				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50015710 (4-Piperazin-1-yl-7-trifluoromethyl-pyrrolo[1,2-a]q...) Show SMILES FC(F)(F)c1ccc2c(c1)nc(N1CCNCC1)c1cccn21 Show InChI InChI=1S/C16H15F3N4/c17-16(18,19)11-3-4-13-12(10-11)21-15(14-2-1-7-23(13)14)22-8-5-20-6-9-22/h1-4,7,10,20H,5-6,8-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50015717 (5-Chloro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-in...) Show SMILES Clc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:8| Show InChI InChI=1S/C13H13ClN2/c14-10-1-2-13-11(7-10)12(8-16-13)9-3-5-15-6-4-9/h1-3,7-8,15-16H,4-6H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptor				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50007406 (1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...) Show SMILES FC(F)(F)c1cccc(c1)N1CCNCC1 Show InChI InChI=1S/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50015714 (3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indol-5-ol ...) Show SMILES Oc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:8| Show InChI InChI=1S/C13H14N2O/c16-10-1-2-13-11(7-10)12(8-15-13)9-3-5-14-6-4-9/h1-3,7-8,14-16H,4-6H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptor				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50015711 (3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indole-5-ca...) Show SMILES N#Cc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:9| Show InChI InChI=1S/C14H13N3/c15-8-10-1-2-14-12(7-10)13(9-17-14)11-3-5-16-6-4-11/h1-3,7,9,16-17H,4-6H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptor				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM81497 (4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrr...) Show SMILES CN1CCN(CC1)c1nc2cc(ccc2n2cccc12)C(F)(F)F Show InChI InChI=1S/C17H17F3N4/c1-22-7-9-23(10-8-22)16-15-3-2-6-24(15)14-5-4-12(17(18,19)20)11-13(14)21-16/h2-6,11H,7-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligand				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50015718 (5-Nitro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-ind...) Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:10| Show InChI InChI=1S/C13H13N3O2/c17-16(18)10-1-2-13-11(7-10)12(8-15-13)9-3-5-14-6-4-9/h1-3,7-8,14-15H,4-6H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptor				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50015710 (4-Piperazin-1-yl-7-trifluoromethyl-pyrrolo[1,2-a]q...) Show SMILES FC(F)(F)c1ccc2c(c1)nc(N1CCNCC1)c1cccn21 Show InChI InChI=1S/C16H15F3N4/c17-16(18,19)11-3-4-13-12(10-11)21-15(14-2-1-7-23(13)14)22-8-5-20-6-9-22/h1-4,7,10,20H,5-6,8-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptor				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM81498 (5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...) Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:9| Show InChI InChI=1S/C14H16N2O/c1-17-11-2-3-14-12(8-11)13(9-16-14)10-4-6-15-7-5-10/h2-4,8-9,15-16H,5-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligand				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50015712 (5-Fluoro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-in...) Show SMILES Fc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:8| Show InChI InChI=1S/C13H13FN2/c14-10-1-2-13-11(7-10)12(8-16-13)9-3-5-15-6-4-9/h1-3,7-8,15-16H,4-6H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptor				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description inhibitory activity against 5-hydroxytryptamine 1C receptor of pig choroid plexus using [3H]-mesulergine as the radioligand				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM31023 (3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...) Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12 |c:2| Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptor				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50007406 (1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...) Show SMILES FC(F)(F)c1cccc(c1)N1CCNCC1 Show InChI InChI=1S/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1C receptor of pig choroid plexus using [3H]-mesulergine as the radiol...				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM81497 (4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrr...) Show SMILES CN1CCN(CC1)c1nc2cc(ccc2n2cccc12)C(F)(F)F Show InChI InChI=1S/C17H17F3N4/c1-22-7-9-23(10-8-22)16-15-3-2-6-24(15)14-5-4-12(17(18,19)20)11-13(14)21-16/h2-6,11H,7-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50015710 (4-Piperazin-1-yl-7-trifluoromethyl-pyrrolo[1,2-a]q...) Show SMILES FC(F)(F)c1ccc2c(c1)nc(N1CCNCC1)c1cccn21 Show InChI InChI=1S/C16H15F3N4/c17-16(18,19)11-3-4-13-12(10-11)21-15(14-2-1-7-23(13)14)22-8-5-20-6-9-22/h1-4,7,10,20H,5-6,8-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligand				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007406 (1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...) Show SMILES FC(F)(F)c1cccc(c1)N1CCNCC1 Show InChI InChI=1S/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptor				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM81498 (5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...) Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:9| Show InChI InChI=1S/C14H16N2O/c1-17-11-2-3-14-12(8-11)13(9-16-14)10-4-6-15-7-5-10/h2-4,8-9,15-16H,5-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1C receptor of pig choroid plexus using [3H]-mesulergine as the radiol...				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50007406 (1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...) Show SMILES FC(F)(F)c1cccc(c1)N1CCNCC1 Show InChI InChI=1S/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigra				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50007406 (1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...) Show SMILES FC(F)(F)c1cccc(c1)N1CCNCC1 Show InChI InChI=1S/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligand				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM84737 (3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...) Show SMILES O=c1ccc2[nH]cc(C3=CCNCC3)c2[nH]1 |t:8| Show InChI InChI=1S/C12H11N3O/c16-11-2-1-10-12(15-11)9(7-14-10)8-3-5-13-6-4-8/h1-3,7,13H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligand				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM84737 (3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...) Show SMILES O=c1ccc2[nH]cc(C3=CCNCC3)c2[nH]1 |t:8| Show InChI InChI=1S/C12H11N3O/c16-11-2-1-10-12(15-11)9(7-14-10)8-3-5-13-6-4-8/h1-3,7,13H,4-6H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptor				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 2 receptor of rat anterior cortex using [3H]ketanserin as the radiolig...				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM81498 (5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...) Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:9| Show InChI InChI=1S/C14H16N2O/c1-17-11-2-3-14-12(8-11)13(9-16-14)10-4-6-15-7-5-10/h2-4,8-9,15-16H,5-7H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 2 receptor of rat anterior cortex using [3H]ketanserin as the radiolig...				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM84737 (3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...) Show SMILES O=c1ccc2[nH]cc(C3=CCNCC3)c2[nH]1 |t:8| Show InChI InChI=1S/C12H11N3O/c16-11-2-1-10-12(15-11)9(7-14-10)8-3-5-13-6-4-8/h1-3,7,13H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1C receptor of pig choroid plexus using [3H]-mesulergine as the radiol...				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM81497 (4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrr...) Show SMILES CN1CCN(CC1)c1nc2cc(ccc2n2cccc12)C(F)(F)F Show InChI InChI=1S/C17H17F3N4/c1-22-7-9-23(10-8-22)16-15-3-2-6-24(15)14-5-4-12(17(18,19)20)11-13(14)21-16/h2-6,11H,7-10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50015710 (4-Piperazin-1-yl-7-trifluoromethyl-pyrrolo[1,2-a]q...) Show SMILES FC(F)(F)c1ccc2c(c1)nc(N1CCNCC1)c1cccn21 Show InChI InChI=1S/C16H15F3N4/c17-16(18,19)11-3-4-13-12(10-11)21-15(14-2-1-7-23(13)14)22-8-5-20-6-9-22/h1-4,7,10,20H,5-6,8-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1C receptor of pig choroid plexus using [3H]-mesulergine as the radiol...				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM81497 (4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrr...) Show SMILES CN1CCN(CC1)c1nc2cc(ccc2n2cccc12)C(F)(F)F Show InChI InChI=1S/C17H17F3N4/c1-22-7-9-23(10-8-22)16-15-3-2-6-24(15)14-5-4-12(17(18,19)20)11-13(14)21-16/h2-6,11H,7-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1C receptor of pig choroid plexus using [3H]-mesulergine as the radiol...				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50015710 (4-Piperazin-1-yl-7-trifluoromethyl-pyrrolo[1,2-a]q...) Show SMILES FC(F)(F)c1ccc2c(c1)nc(N1CCNCC1)c1cccn21 Show InChI InChI=1S/C16H15F3N4/c17-16(18,19)11-3-4-13-12(10-11)21-15(14-2-1-7-23(13)14)22-8-5-20-6-9-22/h1-4,7,10,20H,5-6,8-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 2 receptor of rat anterior cortex using [3H]ketanserin as the radiolig...				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM84737 (3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...) Show SMILES O=c1ccc2[nH]cc(C3=CCNCC3)c2[nH]1 |t:8| Show InChI InChI=1S/C12H11N3O/c16-11-2-1-10-12(15-11)9(7-14-10)8-3-5-13-6-4-8/h1-3,7,13H,4-6H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 2 receptor of rat anterior cortex using [3H]ketanserin as the radiolig...				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM84737 (3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...) Show SMILES O=c1ccc2[nH]cc(C3=CCNCC3)c2[nH]1 |t:8| Show InChI InChI=1S/C12H11N3O/c16-11-2-1-10-12(15-11)9(7-14-10)8-3-5-13-6-4-8/h1-3,7,13H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	56	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigra				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigra				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (RAT)	BDBM84737 (3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...) Show SMILES O=c1ccc2[nH]cc(C3=CCNCC3)c2[nH]1 |t:8| Show InChI InChI=1S/C12H11N3O/c16-11-2-1-10-12(15-11)9(7-14-10)8-3-5-13-6-4-8/h1-3,7,13H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1D receptor of rat substantia nigra				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM84737 (3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...) Show SMILES O=c1ccc2[nH]cc(C3=CCNCC3)c2[nH]1 |t:8| Show InChI InChI=1S/C12H11N3O/c16-11-2-1-10-12(15-11)9(7-14-10)8-3-5-13-6-4-8/h1-3,7,13H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1A receptor of guinea pig hippocampus				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1A receptor of guinea pig hippocampus				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (GUINEA PIG)	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1D receptor of guinea pig substantia nigra				J Med Chem 33: 2087-93 (1990) BindingDB Entry DOI: 10.7270/Q2GQ6WR3
					More data for this Ligand-Target Pair				3D Structure (crystal)