Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytosolic purine 5'-nucleotidase (Homo sapiens) | BDBM50500514 (CHEMBL3746819) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 4.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Non-competitive inhibition of recombinant N-terminal truncated human cytosolic 5'-nucleotidase-2 assessed as inhibition of inosine 5'-monophosphate h... | J Med Chem 58: 9680-96 (2015) Article DOI: 10.1021/acs.jmedchem.5b01616 BindingDB Entry DOI: 10.7270/Q2SF3062 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM68391 ((2R,3S,4S,5R)-2-(6-amino-2-fluoro-9-purinyl)-5-(hy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | 5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Competitive type of inhibition of human 5'-nucleotidase using IMP as substrate assessed as inhibitor constant for free enzyme by Lineweaver-Burk plot... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50522285 (CHEMBL4549109) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.36E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for free enzyme using varying level of IMP as substrate by... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50522285 (CHEMBL4549109) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.82E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Competitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analys... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosolic purine 5'-nucleotidase (Homo sapiens) | BDBM50500511 (CHEMBL3746624) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 7.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Non-competitive inhibition of recombinant N-terminal truncated human cytosolic 5'-nucleotidase-2 assessed as inhibition of inosine 5'-monophosphate h... | J Med Chem 58: 9680-96 (2015) Article DOI: 10.1021/acs.jmedchem.5b01616 BindingDB Entry DOI: 10.7270/Q2SF3062 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50522288 (CHEMBL4518527) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8.43E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Competitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analys... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50500515 (CHEMBL3747390) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 8.93E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Competitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analys... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM68391 ((2R,3S,4S,5R)-2-(6-amino-2-fluoro-9-purinyl)-5-(hy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | 9.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Non-competitive type of inhibition of human 5'-nucleotidase using IMP as substrate assessed as inhibitor constant for enzyme substrate complex by Lin... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50500515 (CHEMBL3747390) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 9.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Competitive inhibition of 5'-nucleotidase (unknown origin) using varying level of IMP as substrate by Lineweaver-Burk plot analysis | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosolic purine 5'-nucleotidase (Homo sapiens) | BDBM50500515 (CHEMBL3747390) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 9.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Competitive inhibition of recombinant N-terminal truncated human cytosolic 5'-nucleotidase-2 assessed as inhibition of inosine 5'-monophosphate hydro... | J Med Chem 58: 9680-96 (2015) Article DOI: 10.1021/acs.jmedchem.5b01616 BindingDB Entry DOI: 10.7270/Q2SF3062 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50522288 (CHEMBL4518527) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 9.95E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for free enzyme using varying level of IMP as substrate by... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50522286 (CHEMBL3237671) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Competitive inhibition of 5'-nucleotidase (unknown origin) using varying level of IMP as substrate by Lineweaver-Burk plot analysis | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50522285 (CHEMBL4549109) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.35E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Uncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot anal... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50500515 (CHEMBL3747390) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 1.48E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for free enzyme using varying level of IMP as substrate by... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosolic purine 5'-nucleotidase (Homo sapiens) | BDBM50500513 (CHEMBL3746419) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 1.65E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Non-competitive inhibition of recombinant N-terminal truncated human cytosolic 5'-nucleotidase-2 assessed as inhibition of inosine 5'-monophosphate h... | J Med Chem 58: 9680-96 (2015) Article DOI: 10.1021/acs.jmedchem.5b01616 BindingDB Entry DOI: 10.7270/Q2SF3062 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50522288 (CHEMBL4518527) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.65E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Uncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot anal... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50522285 (CHEMBL4549109) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Noncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot ana... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosolic purine 5'-nucleotidase (Homo sapiens) | BDBM50500510 (CHEMBL3746211) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Inhibition of recombinant N-terminal truncated human cytosolic 5'-nucleotidase-2 assessed as inhibition of inosine 5'-monophosphate hydrolysis by rap... | J Med Chem 58: 9680-96 (2015) Article DOI: 10.1021/acs.jmedchem.5b01616 BindingDB Entry DOI: 10.7270/Q2SF3062 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50500510 (CHEMBL3746211) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Competitive inhibition of 5'-nucleotidase (unknown origin) using varying level of IMP as substrate by Lineweaver-Burk plot analysis | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50522287 (CHEMBL4438573) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.43E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Competitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analys... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50522287 (CHEMBL4438573) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.43E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for free enzyme using varying level of IMP as substrate by... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50500515 (CHEMBL3747390) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 2.44E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Uncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot anal... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50522288 (CHEMBL4518527) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.52E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Noncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot ana... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosolic purine 5'-nucleotidase (Homo sapiens) | BDBM50500512 (CHEMBL3746515) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 2.78E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Competitive inhibition of recombinant N-terminal truncated human cytosolic 5'-nucleotidase-2 assessed as inhibition of inosine 5'-monophosphate hydro... | J Med Chem 58: 9680-96 (2015) Article DOI: 10.1021/acs.jmedchem.5b01616 BindingDB Entry DOI: 10.7270/Q2SF3062 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50500515 (CHEMBL3747390) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 3.36E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Noncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot ana... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50522287 (CHEMBL4438573) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.98E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Uncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot anal... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50500515 (CHEMBL3747390) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 6.27E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for enzyme substrate complex using varying level of IMP as... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50522287 (CHEMBL4438573) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.97E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Noncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot ana... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50522288 (CHEMBL4518527) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.13E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montpellier Curated by ChEMBL | Assay Description Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for enzyme substrate complex using varying level of IMP as... | Eur J Med Chem 168: 28-44 (2019) Article DOI: 10.1016/j.ejmech.2019.02.040 BindingDB Entry DOI: 10.7270/Q25D8W8P | |||||||||||
More data for this Ligand-Target Pair |