Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194499![]() (US9200020, Table 3 compound 8) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 50 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM194501![]() (US9200020, Table 3 compound 10) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 70 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM194496![]() (US9200020, Table 3 compound 5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 70 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM194500![]() (US9200020, Table 3 compound 9) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM194492![]() (US9200020, Table 3 compound 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM194490![]() (US9200020, Table 1, Compound 1) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM194493![]() (US9200020, Table 3 compound 2) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM194500![]() (US9200020, Table 3 compound 9) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM60887![]() (US9200020, Table 3, Compound 2B) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 100 | -41.6 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM194494![]() (US9200020, Table 3 compound 3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM194499![]() (US9200020, Table 3 compound 8) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 150 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM194501![]() (US9200020, Table 3 compound 10) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 200 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM194496![]() (US9200020, Table 3 compound 5) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 200 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM60890![]() (US9200020, Table 3 compound 5B) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 200 | -39.8 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM194499![]() (US9200020, Table 3 compound 8) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 200 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM194502![]() (US9200020, Table 3 compound 11) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 200 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194496![]() (US9200020, Table 3 compound 5) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 300 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM60880![]() (US9200020, Table 1, Compound 1B) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 300 | -38.7 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM194502![]() (US9200020, Table 3 compound 11) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 300 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM60897![]() (US9200020, Table 3 compound 11B) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 400 | -38.0 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Xanthine-guanine phosphoribosyltransferase (Escherichia coli (strain K12)) | BDBM194503![]() (US9200020, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 400 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM60893![]() (US9200020, Table 3 compound 8B) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 400 | -38.0 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM194493![]() (US9200020, Table 3 compound 2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 500 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM60892![]() (US9200020, Table 3 compound 7B) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 600 | -36.9 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM194497![]() (US9200020, Table 3 compound 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 600 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM60890![]() (US9200020, Table 3 compound 5B) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 700 | -36.5 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM194498![]() (US9200020, Table 3 compound 7) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 700 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194502![]() (US9200020, Table 3 compound 11) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 900 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM194490![]() (US9200020, Table 1, Compound 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM194494![]() (US9200020, Table 3 compound 3) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM194498![]() (US9200020, Table 3 compound 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194501![]() (US9200020, Table 3 compound 10) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194492![]() (US9200020, Table 3 compound 1) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM60894![]() (US9200020, Table 3 compound 9B) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 1.60E+3 | -34.4 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM194492![]() (US9200020, Table 3 compound 1) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM60886![]() (US9200020, Table 3, Compound 1B) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 1.90E+3 | -34.0 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM60890![]() (US9200020, Table 3 compound 5B) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 2.40E+3 | -33.4 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM60896![]() (US9200020, Table 3 compound 10B) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 2.60E+3 | -33.2 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM60886![]() (US9200020, Table 3, Compound 1B) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 2.60E+3 | -33.2 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM60897![]() (US9200020, Table 3 compound 11B) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 3.00E+3 | -32.8 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM194491![]() (US9200020, Table 1, Compound 2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM60880![]() (US9200020, Table 1, Compound 1B) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 3.60E+3 | -32.3 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194493![]() (US9200020, Table 3 compound 2) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM194497![]() (US9200020, Table 3 compound 6) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM60894![]() (US9200020, Table 3 compound 9B) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 5.40E+3 | -31.3 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM60896![]() (US9200020, Table 3 compound 10B) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 5.50E+3 | -31.2 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM60891![]() (US9200020, Table 3 compound 6B) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 6.00E+3 | -31.0 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194497![]() (US9200020, Table 3 compound 6) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM60886![]() (US9200020, Table 3, Compound 1B) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 1.10E+4 | -29.4 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194491![]() (US9200020, Table 1, Compound 2) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair |
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